IE38875B1 - Prostanoic acid derivatives - Google Patents
Prostanoic acid derivativesInfo
- Publication number
- IE38875B1 IE38875B1 IE02339/73A IE233973A IE38875B1 IE 38875 B1 IE38875 B1 IE 38875B1 IE 02339/73 A IE02339/73 A IE 02339/73A IE 233973 A IE233973 A IE 233973A IE 38875 B1 IE38875 B1 IE 38875B1
- Authority
- IE
- Ireland
- Prior art keywords
- compound
- mixture
- compounds
- constituent
- alkoxy
- Prior art date
Links
- WGJJROVFWIXTPA-OALUTQOASA-N prostanoic acid Chemical class CCCCCCCC[C@H]1CCC[C@@H]1CCCCCCC(O)=O WGJJROVFWIXTPA-OALUTQOASA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 19
- 239000000470 constituent Substances 0.000 abstract 10
- 239000000203 mixture Substances 0.000 abstract 10
- 125000003545 alkoxy group Chemical group 0.000 abstract 3
- 229930194542 Keto Natural products 0.000 abstract 2
- 101100323029 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) alc-1 gene Proteins 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000468 ketone group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- HTSGKJQDMSTCGS-UHFFFAOYSA-N 1,4-bis(4-chlorophenyl)-2-(4-methylphenyl)sulfonylbutane-1,4-dione Chemical compound C1=CC(C)=CC=C1S(=O)(=O)C(C(=O)C=1C=CC(Cl)=CC=1)CC(=O)C1=CC=C(Cl)C=C1 HTSGKJQDMSTCGS-UHFFFAOYSA-N 0.000 abstract 1
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- FKLJPTJMIBLJAV-UHFFFAOYSA-N Compound IV Chemical compound O1N=C(C)C=C1CCCCCCCOC1=CC=C(C=2OCCN=2)C=C1 FKLJPTJMIBLJAV-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 101150104410 alc gene Proteins 0.000 abstract 1
- 230000001595 contractor effect Effects 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- NLFBCYMMUAKCPC-KQQUZDAGSA-N ethyl (e)-3-[3-amino-2-cyano-1-[(e)-3-ethoxy-3-oxoprop-1-enyl]sulfanyl-3-oxoprop-1-enyl]sulfanylprop-2-enoate Chemical compound CCOC(=O)\C=C\SC(=C(C#N)C(N)=O)S\C=C\C(=O)OCC NLFBCYMMUAKCPC-KQQUZDAGSA-N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 230000020477 pH reduction Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7246324A FR2211223B1 (ja) | 1972-12-27 | 1972-12-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38875L IE38875L (en) | 1974-06-27 |
| IE38875B1 true IE38875B1 (en) | 1978-06-21 |
Family
ID=9109325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE02339/73A IE38875B1 (en) | 1972-12-27 | 1973-12-28 | Prostanoic acid derivatives |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5724343B2 (ja) |
| BE (1) | BE808969A (ja) |
| CA (1) | CA1018972A (ja) |
| CH (2) | CH590226A5 (ja) |
| DD (1) | DD108268A5 (ja) |
| DE (1) | DE2364706C2 (ja) |
| ES (1) | ES421790A1 (ja) |
| FR (1) | FR2211223B1 (ja) |
| GB (1) | GB1438130A (ja) |
| IE (1) | IE38875B1 (ja) |
| IL (1) | IL43832A (ja) |
| NL (1) | NL7317745A (ja) |
| SU (1) | SU668597A3 (ja) |
| ZA (1) | ZA739650B (ja) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4091015A (en) * | 1972-10-27 | 1978-05-23 | American Home Products Corporation | 15-Substituted prostanoic acids |
| US3922302A (en) * | 1973-07-26 | 1975-11-25 | American Home Prod | 15-Ethynyl-11-deoxy PGE |
| US4022821A (en) * | 1974-04-18 | 1977-05-10 | American Home Products Corporation | 15-Substituted prostanoic acid |
| US4065494A (en) * | 1975-04-17 | 1977-12-27 | American Home Products Corporation | 15-Substituted prostanoic acids |
-
1972
- 1972-12-27 FR FR7246324A patent/FR2211223B1/fr not_active Expired
-
1973
- 1973-12-17 IL IL43832A patent/IL43832A/en unknown
- 1973-12-21 DD DD175629A patent/DD108268A5/xx unknown
- 1973-12-21 BE BE139155A patent/BE808969A/xx not_active IP Right Cessation
- 1973-12-21 ZA ZA00739650A patent/ZA739650B/xx unknown
- 1973-12-24 CA CA188,897A patent/CA1018972A/fr not_active Expired
- 1973-12-24 SU SU731978756A patent/SU668597A3/ru active
- 1973-12-26 JP JP14414673A patent/JPS5724343B2/ja not_active Expired
- 1973-12-26 ES ES421790A patent/ES421790A1/es not_active Expired
- 1973-12-27 GB GB5981973A patent/GB1438130A/en not_active Expired
- 1973-12-27 NL NL7317745A patent/NL7317745A/xx not_active Application Discontinuation
- 1973-12-27 DE DE2364706A patent/DE2364706C2/de not_active Expired
- 1973-12-27 CH CH1435676A patent/CH590226A5/xx not_active IP Right Cessation
- 1973-12-27 CH CH1816573A patent/CH590225A5/xx not_active IP Right Cessation
- 1973-12-28 IE IE02339/73A patent/IE38875B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH590226A5 (ja) | 1977-07-29 |
| FR2211223A1 (ja) | 1974-07-19 |
| ZA739650B (en) | 1975-02-26 |
| AU6396873A (en) | 1975-07-03 |
| GB1438130A (ja) | 1976-06-03 |
| BE808969A (fr) | 1974-06-21 |
| DE2364706C2 (de) | 1982-07-08 |
| CA1018972A (fr) | 1977-10-11 |
| DE2364706A1 (de) | 1974-07-04 |
| CH590225A5 (ja) | 1977-07-29 |
| IL43832A0 (en) | 1974-03-14 |
| FR2211223B1 (ja) | 1976-04-23 |
| JPS5724343B2 (ja) | 1982-05-24 |
| NL7317745A (ja) | 1974-07-01 |
| JPS5046649A (ja) | 1975-04-25 |
| ES421790A1 (es) | 1976-04-01 |
| IL43832A (en) | 1977-03-31 |
| IE38875L (en) | 1974-06-27 |
| SU668597A3 (ru) | 1979-06-15 |
| DD108268A5 (ja) | 1974-09-12 |
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