IE38536B1 - Prostaglandin type compounds - Google Patents
Prostaglandin type compoundsInfo
- Publication number
- IE38536B1 IE38536B1 IE211473A IE211473A IE38536B1 IE 38536 B1 IE38536 B1 IE 38536B1 IE 211473 A IE211473 A IE 211473A IE 211473 A IE211473 A IE 211473A IE 38536 B1 IE38536 B1 IE 38536B1
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- compound
- nov
- alkyl
- type compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 150000003180 prostaglandins Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 230000003243 anti-lipolytic effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 210000002460 smooth muscle Anatomy 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
Abstract
1409936 Prostaglandins ROUSSEL UCLAF 23 Nov 1973 [23 Nov 1972] 54533/73 Heading C2C Novel compounds of Formula I (in which R=H or C 1-4 alkyl, R 1 = H or C 1-2 alkyl, R 2 = H or α-tetrahydropyranyl, m = 3, 4 or 5 and n=2, 3 or 4) and the base salts of those compounds in which R = H, are prepared by reacting a compound of Formula II with a compound of formula and, if desired, converting a resulting compound I in which R = H into a base salt. Pharmaceutical compositions having hypotensive, smooth muscle contracting, antibron - choconstrictive and antilipolytic activity, for oral, parenteral, rectal or topical administration, comprise one of the above novel compounds together with one or more pharmaceutical carriers or excipients. The compositions may also be in an aerosol form.
[GB1409936A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7241604A FR2207701B1 (en) | 1972-11-23 | 1972-11-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE38536L IE38536L (en) | 1974-05-23 |
| IE38536B1 true IE38536B1 (en) | 1978-04-12 |
Family
ID=9107575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE211473A IE38536B1 (en) | 1972-11-23 | 1973-11-21 | Prostaglandin type compounds |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS49100062A (en) |
| BE (1) | BE807668A (en) |
| CA (1) | CA1018971A (en) |
| CH (1) | CH581100A5 (en) |
| DE (1) | DE2358420A1 (en) |
| FR (1) | FR2207701B1 (en) |
| GB (1) | GB1409936A (en) |
| IE (1) | IE38536B1 (en) |
| NL (1) | NL7316086A (en) |
-
1972
- 1972-11-23 FR FR7241604A patent/FR2207701B1/fr not_active Expired
-
1973
- 1973-11-21 CH CH1636873A patent/CH581100A5/xx not_active IP Right Cessation
- 1973-11-21 IE IE211473A patent/IE38536B1/en unknown
- 1973-11-21 JP JP13033173A patent/JPS49100062A/ja active Pending
- 1973-11-22 CA CA186,510A patent/CA1018971A/en not_active Expired
- 1973-11-22 BE BE138048A patent/BE807668A/en unknown
- 1973-11-23 NL NL7316086A patent/NL7316086A/xx not_active Application Discontinuation
- 1973-11-23 GB GB5453373A patent/GB1409936A/en not_active Expired
- 1973-11-23 DE DE19732358420 patent/DE2358420A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2207701B1 (en) | 1975-11-28 |
| FR2207701A1 (en) | 1974-06-21 |
| JPS49100062A (en) | 1974-09-20 |
| CH581100A5 (en) | 1976-10-29 |
| DE2358420A1 (en) | 1974-05-30 |
| GB1409936A (en) | 1975-10-15 |
| NL7316086A (en) | 1974-05-27 |
| IE38536L (en) | 1974-05-23 |
| CA1018971A (en) | 1977-10-11 |
| BE807668A (en) | 1974-05-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1439724A (en) | Berbine derivatives and pharmaceutical compositions containing them | |
| GB1252329A (en) | ||
| IE34314L (en) | Dibenzodioxocine derivatives | |
| GB1409648A (en) | Substituted pyrrolidinemethanol compounds and pharmaceutical compositions thereof | |
| IE38536B1 (en) | Prostaglandin type compounds | |
| GB1394619A (en) | Imides | |
| IE36597L (en) | Preparing a 1,2-dihydrophthalazine | |
| GB1263116A (en) | Chloramphenicol and thiamphenicol derivatives | |
| GB1503447A (en) | Dl-and 8r-9-fluoro-prostadienoic acid derivatives and process | |
| IE35570B1 (en) | Pyrimido isoquinolines | |
| GB1393228A (en) | 2-2-2-methyl-5-nitro-1-imidazolyl-ethyl-2-thiopseudoureas and related compounds | |
| GB1509457A (en) | Pyridine derivatives | |
| IE35223L (en) | Bis-basic ethers of 2, 6- and 2, 7-dihydroxy-anthraquinones | |
| IE41835L (en) | Prostadienoic acid derivatives | |
| GB1512930A (en) | Substituted 4-hydroxybenzylidene malononitriles | |
| SE7408868L (en) | ||
| IE38261B1 (en) | Benzocycloheptathiophene derivatives | |
| GB1322069A (en) | Aminoalkanoylaminocyclohexane derivatives | |
| GB1369888A (en) | Substituted amidines | |
| ES477754A1 (en) | Novel derivatives of eburnamonine | |
| US4176236A (en) | Composition and process | |
| GB1527941A (en) | 1-(3-phenylpropyl)-4-(beta-alkoxyacryloyl)piperazine derivatives | |
| GB1525190A (en) | Prosta-4,13-dienoic acid derivatives | |
| GB1294825A (en) | ||
| GB1350645A (en) | Phenylacetic acid derivatives a method for their preparation and the applications thereof |