IE38195B1 - New phenylacetic and phenylpropionic acid derivatives - Google Patents

New phenylacetic and phenylpropionic acid derivatives

Info

Publication number
IE38195B1
IE38195B1 IE1565/73A IE156573A IE38195B1 IE 38195 B1 IE38195 B1 IE 38195B1 IE 1565/73 A IE1565/73 A IE 1565/73A IE 156573 A IE156573 A IE 156573A IE 38195 B1 IE38195 B1 IE 38195B1
Authority
IE
Ireland
Prior art keywords
formula
acid derivatives
compounds
phenylpropionic acid
sept
Prior art date
Application number
IE1565/73A
Other versions
IE38195L (en
Original Assignee
Rhone Poulenc Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sa filed Critical Rhone Poulenc Sa
Publication of IE38195L publication Critical patent/IE38195L/en
Publication of IE38195B1 publication Critical patent/IE38195B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

1383460 Phenylacetic and phenylpropionic acid derivatives RHONE-POULENC SA 6 Sept 1973 [7 Sept 1972] 41943/73 Heading C2C The invention comprises compounds of the formula wherein R is H or CH 3 , and salts thereof. They may be obtained by reacting under Friedel- Crafts conditions a compound of the formula with thiophene and hydrolysing the resulting compound of the formula to give the corresponding acid, and optionally converting the acid into a salt thereof. The compounds of Formula II may be obtained by treating the corresponding acids with thionyl chloride. The compounds of Formula I have antiinflammatory, analgesic, anti-pyretic and thrombolytic properties. They may be applied orally, parenterally, rectally or topically in conventional forms. [GB1383460A]
IE1565/73A 1972-09-07 1973-09-04 New phenylacetic and phenylpropionic acid derivatives IE38195B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7231723A FR2197583B1 (en) 1972-09-07 1972-09-07

Publications (2)

Publication Number Publication Date
IE38195L IE38195L (en) 1974-03-07
IE38195B1 true IE38195B1 (en) 1978-01-18

Family

ID=9103971

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1565/73A IE38195B1 (en) 1972-09-07 1973-09-04 New phenylacetic and phenylpropionic acid derivatives

Country Status (13)

Country Link
JP (1) JPS5512026B2 (en)
AU (1) AU471383B2 (en)
BE (1) BE804551A (en)
CA (1) CA985290A (en)
CH (1) CH572480A5 (en)
DE (1) DE2345276C3 (en)
FR (1) FR2197583B1 (en)
GB (1) GB1383460A (en)
HU (1) HU166292B (en)
IE (1) IE38195B1 (en)
LU (1) LU68369A1 (en)
NL (1) NL7311965A (en)
ZA (1) ZA736058B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8310221A8 (en) * 1982-02-04 1995-10-31 Wellcome Found Process for obtaining new pyridil compounds
TW200702824A (en) * 2005-06-02 2007-01-16 Koninkl Philips Electronics Nv LED assembly and module

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR6574940D0 (en) * 1964-11-27 1973-08-07 Merck & Co Inc PROCESS TO MAKE PHENYL-ACETIC ACIDS
US3657432A (en) * 1969-06-25 1972-04-18 Merck & Co Inc Anti-inflammatory salicylic acid derivatives

Also Published As

Publication number Publication date
JPS5512026B2 (en) 1980-03-29
DE2345276C3 (en) 1982-04-22
DE2345276B2 (en) 1981-07-23
AU471383B2 (en) 1976-04-15
CA985290A (en) 1976-03-09
NL7311965A (en) 1974-03-11
BE804551A (en) 1974-03-06
IE38195L (en) 1974-03-07
FR2197583B1 (en) 1975-10-17
AU6000673A (en) 1975-03-06
ZA736058B (en) 1974-08-28
HU166292B (en) 1975-02-28
LU68369A1 (en) 1974-03-14
FR2197583A1 (en) 1974-03-29
CH572480A5 (en) 1976-02-13
GB1383460A (en) 1974-02-12
JPS4985064A (en) 1974-08-15
DE2345276A1 (en) 1974-04-25

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