IE37131B1 - Insulin derivatives - Google Patents

Insulin derivatives

Info

Publication number
IE37131B1
IE37131B1 IE1539/72A IE153972A IE37131B1 IE 37131 B1 IE37131 B1 IE 37131B1 IE 1539/72 A IE1539/72 A IE 1539/72A IE 153972 A IE153972 A IE 153972A IE 37131 B1 IE37131 B1 IE 37131B1
Authority
IE
Ireland
Prior art keywords
insulins
primary amino
phenylalanine
nov
physiologically acceptable
Prior art date
Application number
IE1539/72A
Other versions
IE37131L (en
Original Assignee
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Dev filed Critical Nat Res Dev
Publication of IE37131L publication Critical patent/IE37131L/en
Publication of IE37131B1 publication Critical patent/IE37131B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1408757 Insulins NATIONAL RESEARCH DEVELOPMENT CORP 8 Nov 1972 [18 Nov 1971 (2)] 53622/71 and 53623/71 Heading C3H [Also in Division A5] Physiologically acceptable substantially pure N-substituted insulins in which the primary amino groups of the A 1 (glycine) amino acid units, and optionally also the primary amino group of one or both of the B 1 (phenylalanine) and B 29 (lysine) amino acid units, carry a carbamoyl group, N-substitution being absent from any positions other than said primary amino groups, and physiologically acceptable substantially pure B 1 (phenylalanine)-N-monocarbamoyl insulin are prepared by reacting insulins with carbamoylating agents, for example alkali metal cyanates, and separating the substituted insulins from the reaction mixtures. [GB1408757A]
IE1539/72A 1971-11-18 1972-11-10 Insulin derivatives IE37131B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5362371 1971-11-18
GB5362271A GB1408757A (en) 1971-11-18 1971-11-18 Insulin derivatives 35and hydrocarbons including normal paraffins a gasoline product of higher octane number than said gasoline

Publications (2)

Publication Number Publication Date
IE37131L IE37131L (en) 1973-05-18
IE37131B1 true IE37131B1 (en) 1977-05-11

Family

ID=26267305

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1539/72A IE37131B1 (en) 1971-11-18 1972-11-10 Insulin derivatives

Country Status (11)

Country Link
JP (1) JPS4861493A (en)
AU (1) AU475066B2 (en)
BE (1) BE791585A (en)
CA (1) CA1002517A (en)
CH (2) CH564519A5 (en)
DE (1) DE2256574A1 (en)
FR (1) FR2160619B1 (en)
GB (1) GB1408757A (en)
IE (1) IE37131B1 (en)
NL (1) NL7215599A (en)
SE (2) SE396947B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2141679A (en) * 1983-04-23 1985-01-03 William Brydson Motor vehicle turntable

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE36225B1 (en) * 1971-01-28 1976-09-15 Nat Res Dev Improvements relating to insulin derivatives

Also Published As

Publication number Publication date
CH574393A5 (en) 1976-04-15
SE7511703L (en) 1975-10-17
BE791585A (en) 1973-05-17
CH564519A5 (en) 1975-07-31
AU4887272A (en) 1974-05-16
AU475066B2 (en) 1976-08-12
DE2256574A1 (en) 1973-05-30
SE396947B (en) 1977-10-10
FR2160619B1 (en) 1977-04-15
CA1002517A (en) 1976-12-28
JPS4861493A (en) 1973-08-28
NL7215599A (en) 1973-05-22
GB1408757A (en) 1975-10-01
IE37131L (en) 1973-05-18
FR2160619A1 (en) 1973-06-29

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