IE36383B1 - Improvements in or relating to ortho-disubstituted arylguanidines process for their preparation and applications thereof - Google Patents
Improvements in or relating to ortho-disubstituted arylguanidines process for their preparation and applications thereofInfo
- Publication number
- IE36383B1 IE36383B1 IE690/72A IE69072A IE36383B1 IE 36383 B1 IE36383 B1 IE 36383B1 IE 690/72 A IE690/72 A IE 690/72A IE 69072 A IE69072 A IE 69072A IE 36383 B1 IE36383 B1 IE 36383B1
- Authority
- IE
- Ireland
- Prior art keywords
- arylguanidines
- preparation
- dichlorophenyl
- disubstituted
- ortho
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- -1 2,6 - dichlorophenyl Chemical group 0.000 abstract 1
- 101100037762 Caenorhabditis elegans rnh-2 gene Proteins 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- QXNWSWDAHZQGRO-UHFFFAOYSA-N methyl n'-(2,6-dichlorophenyl)carbamimidothioate Chemical compound CSC(N)=NC1=C(Cl)C=CC=C1Cl QXNWSWDAHZQGRO-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1851071*[A GB1356470A (en) | 1971-06-02 | 1971-06-02 | Ortho-disubstituted aryl-guanidines process for their preparation and applications thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36383L IE36383L (en) | 1972-12-02 |
| IE36383B1 true IE36383B1 (en) | 1976-10-27 |
Family
ID=10113667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE690/72A IE36383B1 (en) | 1971-06-02 | 1972-05-23 | Improvements in or relating to ortho-disubstituted arylguanidines process for their preparation and applications thereof |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5521740B2 (cs) |
| AT (1) | AT314555B (cs) |
| AU (1) | AU462814B2 (cs) |
| BE (1) | BE784259A (cs) |
| CA (1) | CA970391A (cs) |
| CH (1) | CH554319A (cs) |
| DE (1) | DE2226590A1 (cs) |
| DK (1) | DK129987B (cs) |
| FR (1) | FR2140060B1 (cs) |
| GB (1) | GB1356470A (cs) |
| IE (1) | IE36383B1 (cs) |
| LU (1) | LU65442A1 (cs) |
| NL (1) | NL7207269A (cs) |
| OA (1) | OA04093A (cs) |
| SE (1) | SE375524B (cs) |
| ZA (1) | ZA723523B (cs) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2549049B1 (fr) * | 1983-07-13 | 1986-06-20 | Chauvin Blache Lab | Nouvelles amidines, leur procede de preparation et leur application therapeutique |
| JP2015518855A (ja) * | 2012-05-23 | 2015-07-06 | セリックスビオ プライヴェート リミテッド | 粘膜炎の治療のための組成物および方法 |
| US9108942B1 (en) | 2014-11-05 | 2015-08-18 | Mahesh Kandula | Compositions and methods for the treatment of moderate to severe pain |
| WO2014091384A2 (en) * | 2012-12-12 | 2014-06-19 | Mahesh Kandula | Compositions and methods for the treatment of mucositis |
| US9333187B1 (en) | 2013-05-15 | 2016-05-10 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory bowel disease |
| WO2014195961A1 (en) | 2013-06-04 | 2014-12-11 | Mahesh Kandula | Compositions and methods for the treatment of diabetes and pre-diabetes |
| US9096537B1 (en) | 2014-12-31 | 2015-08-04 | Mahesh Kandula | Compositions and methods for the treatment of mucositis |
| EP3240779B1 (en) | 2014-09-26 | 2020-10-28 | Cellixbio Private Limited | Compositions and methods for the treatment of epilepsy and neurological disorders |
| SG11201702554QA (en) | 2014-09-29 | 2017-04-27 | Cellix Bio Private Ltd | Compositions and methods for the treatment of multiple sclerosis |
| WO2016098119A1 (en) | 2014-10-27 | 2016-06-23 | Cellix Bio Private Limited | Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis |
| US9932294B2 (en) | 2014-12-01 | 2018-04-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of multiple sclerosis |
| US9206111B1 (en) | 2014-12-17 | 2015-12-08 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological diseases |
| CA2973178C (en) | 2015-01-06 | 2022-11-01 | Cellix Bio Private Limited | Bupivacaine derivatives and their use in the treatment of inflammation and pain |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1542792B2 (de) * | 1965-11-09 | 1974-08-01 | Bayer Ag, 5090 Leverkusen | Verwendung von Monoarylguanidinen zur Abwehr von Vögeln, Nagetieren und hasenartigen Tieren |
| DE1619538B1 (de) * | 1967-08-04 | 1971-06-24 | Bayer Ag | Verfahren zum Färben von Fasermaterialien aus Polyacrylnitril oder acrylnitrilhaltigen Mischpolymerisaten |
-
1971
- 1971-06-02 GB GB1851071*[A patent/GB1356470A/en not_active Expired
-
1972
- 1972-05-23 CH CH755872A patent/CH554319A/fr not_active IP Right Cessation
- 1972-05-23 IE IE690/72A patent/IE36383B1/xx unknown
- 1972-05-23 ZA ZA723523A patent/ZA723523B/xx unknown
- 1972-05-26 DK DK265372AA patent/DK129987B/da unknown
- 1972-05-27 OA OA54584A patent/OA04093A/xx unknown
- 1972-05-29 JP JP5255972A patent/JPS5521740B2/ja not_active Expired
- 1972-05-29 AT AT463372A patent/AT314555B/de not_active IP Right Cessation
- 1972-05-29 FR FR7219188A patent/FR2140060B1/fr not_active Expired
- 1972-05-29 NL NL7207269A patent/NL7207269A/xx not_active Application Discontinuation
- 1972-05-30 SE SE7207080A patent/SE375524B/xx unknown
- 1972-05-31 DE DE19722226590 patent/DE2226590A1/de not_active Withdrawn
- 1972-05-31 LU LU65442D patent/LU65442A1/xx unknown
- 1972-06-01 BE BE784259A patent/BE784259A/xx unknown
- 1972-06-02 AU AU43059/72A patent/AU462814B2/en not_active Expired
- 1972-06-02 CA CA143,747A patent/CA970391A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE2226590A1 (de) | 1972-12-14 |
| FR2140060A1 (cs) | 1973-01-12 |
| JPS5521740B2 (cs) | 1980-06-12 |
| ZA723523B (en) | 1973-03-28 |
| AU462814B2 (en) | 1975-06-23 |
| OA04093A (fr) | 1979-10-30 |
| DK129987C (cs) | 1975-06-02 |
| AU4305972A (en) | 1973-12-13 |
| SE375524B (cs) | 1975-04-21 |
| BE784259A (fr) | 1972-10-02 |
| FR2140060B1 (cs) | 1975-10-17 |
| LU65442A1 (cs) | 1972-08-24 |
| AT314555B (de) | 1974-04-10 |
| JPS4828434A (cs) | 1973-04-14 |
| DK129987B (da) | 1974-12-09 |
| NL7207269A (cs) | 1972-12-05 |
| IE36383L (en) | 1972-12-02 |
| CA970391A (en) | 1975-07-01 |
| GB1356470A (en) | 1974-06-12 |
| CH554319A (fr) | 1974-09-30 |
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