IE35409B1 - Production of penicillamine and its homologues - Google Patents
Production of penicillamine and its homologuesInfo
- Publication number
- IE35409B1 IE35409B1 IE829/71A IE82971A IE35409B1 IE 35409 B1 IE35409 B1 IE 35409B1 IE 829/71 A IE829/71 A IE 829/71A IE 82971 A IE82971 A IE 82971A IE 35409 B1 IE35409 B1 IE 35409B1
- Authority
- IE
- Ireland
- Prior art keywords
- penicillamine
- salt
- thiazolidine
- converting
- iii
- Prior art date
Links
- LJRDOKAZOAKLDU-UDXJMMFXSA-N (2s,3s,4r,5r,6r)-5-amino-2-(aminomethyl)-6-[(2r,3s,4r,5s)-5-[(1r,2r,3s,5r,6s)-3,5-diamino-2-[(2s,3r,4r,5s,6r)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol;sulfuric ac Chemical compound OS(O)(=O)=O.N[C@@H]1[C@@H](O)[C@H](O)[C@H](CN)O[C@@H]1O[C@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](N)C[C@@H](N)[C@@H]2O)O[C@@H]2[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O2)N)O[C@@H]1CO LJRDOKAZOAKLDU-UDXJMMFXSA-N 0.000 title abstract 4
- 229960001639 penicillamine Drugs 0.000 title abstract 4
- 150000003863 ammonium salts Chemical class 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- DZLNHFMRPBPULJ-UHFFFAOYSA-N thioproline Chemical compound OC(=O)C1CSCN1 DZLNHFMRPBPULJ-UHFFFAOYSA-N 0.000 abstract 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- LELOWRISYMNNSU-UHFFFAOYSA-N hydrogen cyanide Chemical compound N#C LELOWRISYMNNSU-UHFFFAOYSA-N 0.000 abstract 2
- PRSDPVKGJUBIAA-UHFFFAOYSA-N 1,3-thiazolidine-4-carbonitrile Chemical compound N#CC1CSCN1 PRSDPVKGJUBIAA-UHFFFAOYSA-N 0.000 abstract 1
- AIOMGEMZFLRFJE-UHFFFAOYSA-N 1,3-thiazolidine-4-carboxamide Chemical compound NC(=O)C1CSCN1 AIOMGEMZFLRFJE-UHFFFAOYSA-N 0.000 abstract 1
- JLLDUMMFTKVTLS-UHFFFAOYSA-N 5,5-dimethyl-2-propan-2-yl-1,3-thiazolidine-4-carboxylic acid Chemical compound CC(C)C1NC(C(O)=O)C(C)(C)S1 JLLDUMMFTKVTLS-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- -1 aliphatic aldehyde Chemical class 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 229910021529 ammonia Inorganic materials 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2032952A DE2032952C3 (de) | 1970-07-03 | 1970-07-03 | Verfahren zur Herstellung von D,L-Penicillamin |
| DE19712123232 DE2123232C3 (de) | 1971-05-11 | 1971-05-11 | Verfahren zur Herstellung von DJ^-Penicillamin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE35409L IE35409L (en) | 1972-01-03 |
| IE35409B1 true IE35409B1 (en) | 1976-02-04 |
Family
ID=25759383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE829/71A IE35409B1 (en) | 1970-07-03 | 1971-06-29 | Production of penicillamine and its homologues |
Country Status (16)
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH540234A (de) * | 1968-09-06 | 1973-08-15 | Degussa | Verfahren zur Herstellung von Penicillamin |
-
1971
- 1971-06-05 ES ES71391971A patent/ES391971A1/es not_active Expired
- 1971-06-14 DK DK288571A patent/DK145180C/da active
- 1971-06-21 NL NLAANVRAGE7108503,A patent/NL171891C/xx not_active IP Right Cessation
- 1971-06-24 GB GB2963571A patent/GB1346198A/en not_active Expired
- 1971-06-25 RO RO67459A patent/RO59924A/ro unknown
- 1971-06-28 IL IL37171A patent/IL37171A/xx unknown
- 1971-06-29 IE IE829/71A patent/IE35409B1/xx unknown
- 1971-07-01 BE BE769390A patent/BE769390A/xx not_active IP Right Cessation
- 1971-07-02 AT AT819973*1A patent/AT322523B/de not_active IP Right Cessation
- 1971-07-02 SU SU1677804A patent/SU508207A3/ru active
- 1971-07-02 AT AT576871A patent/AT313864B/de not_active IP Right Cessation
- 1971-07-02 SE SE7108614A patent/SE395001B/xx unknown
- 1971-07-02 CH CH979471A patent/CH575388A5/xx not_active IP Right Cessation
- 1971-07-02 IT IT51366/71A patent/IT1035036B/it active
- 1971-07-03 JP JP4917971A patent/JPS544936B1/ja active Pending
- 1971-07-05 FR FR7124505A patent/FR2100257A5/fr not_active Expired
- 1971-07-05 CA CA117,354A patent/CA949977A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK145180C (da) | 1983-02-28 |
| SE395001B (sv) | 1977-07-25 |
| AT313864B (de) | 1974-03-11 |
| SU508207A3 (ru) | 1976-03-25 |
| IL37171A0 (en) | 1971-08-25 |
| RO59924A (enrdf_load_stackoverflow) | 1976-07-15 |
| IE35409L (en) | 1972-01-03 |
| JPS544936B1 (enrdf_load_stackoverflow) | 1979-03-12 |
| FR2100257A5 (enrdf_load_stackoverflow) | 1972-03-17 |
| BE769390A (fr) | 1972-01-03 |
| IT1035036B (it) | 1979-10-20 |
| NL171891C (nl) | 1983-06-01 |
| CA949977A (en) | 1974-06-25 |
| NL171891B (nl) | 1983-01-03 |
| AT322523B (de) | 1975-05-26 |
| NL7108503A (enrdf_load_stackoverflow) | 1972-01-05 |
| CH575388A5 (enrdf_load_stackoverflow) | 1976-05-14 |
| ES391971A1 (es) | 1974-05-01 |
| IL37171A (en) | 1974-10-22 |
| GB1346198A (en) | 1974-02-06 |
| DK145180B (da) | 1982-09-27 |
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