IE34211B1 - Improvements in or relating to sulphonylureas - Google Patents

Improvements in or relating to sulphonylureas

Info

Publication number
IE34211B1
IE34211B1 IE52970A IE52970A IE34211B1 IE 34211 B1 IE34211 B1 IE 34211B1 IE 52970 A IE52970 A IE 52970A IE 52970 A IE52970 A IE 52970A IE 34211 B1 IE34211 B1 IE 34211B1
Authority
IE
Ireland
Prior art keywords
alkyl
alkoxyalkyl
dihydro
alkenyl
cyclohexyl
Prior art date
Application number
IE52970A
Other versions
IE34211L (en
Original Assignee
Novo Terapeutisk Labor As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Terapeutisk Labor As filed Critical Novo Terapeutisk Labor As
Publication of IE34211L publication Critical patent/IE34211L/en
Publication of IE34211B1 publication Critical patent/IE34211B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Derivs. are of formula : and their salts (where R1 is lower-alkyl, -alkenyl or -alkoxyalkyl, lower phenylalkyl, lower cyclohexylalkyl, cycloheptyl and cyclooctyl-methyl, cyclohexyl, lower cyclohexenylalkyl, 5-8C cycloalkyl, endoalkylenecyclohexyl, -cyclohexenyl, -cyclohexylmethyl, or -cyclohexenylmethyl with 1 or 2 C in the endo-alkylene chain; (di) or tri-) lower alkyl cyclohexyl, (di) lower alkyl cyclohexenyl; lower alkyl cyclohexyl, adamantyl or nortricyclyl; Y is a straight or branched chain 2-4C hydrocarbon, pref. -CH2-CH2-; R2 is H, lower alkyl, -alkoxyalkyl or -alkenyl, -alkoxy, alkenoxy, -thioalkoxy, -alkoxyalkoxy or benzyloxy, halogen or trifluoromethyl; U is a 2-4C chain contg. (dihydro)benzofuran, (dihydro) benzopyran, dihydro- or tetrahydro-benzoxepin; R3 and R4 are H, lower-alkyl, -alkoxyalkyl, -alkenyl, -alkoxy, -alkenoxy, phenyl or benzyloxy). [FR2051513A1]
IE52970A 1969-05-09 1970-04-27 Improvements in or relating to sulphonylureas IE34211B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2388869 1969-05-09
GB4276369 1969-08-27
GB5743469 1969-11-24

Publications (2)

Publication Number Publication Date
IE34211L IE34211L (en) 1970-11-09
IE34211B1 true IE34211B1 (en) 1975-03-05

Family

ID=27258272

Family Applications (1)

Application Number Title Priority Date Filing Date
IE52970A IE34211B1 (en) 1969-05-09 1970-04-27 Improvements in or relating to sulphonylureas

Country Status (12)

Country Link
JP (1) JPS4945868B1 (en)
CA (1) CA954525A (en)
CH (1) CH557810A (en)
DE (2) DE2021828C3 (en)
DK (1) DK128244C (en)
ES (5) ES379494A1 (en)
FI (1) FI54476C (en)
FR (1) FR2051513A1 (en)
IE (1) IE34211B1 (en)
NL (1) NL7006726A (en)
NO (1) NO130825C (en)
SE (1) SE374743B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2225544A1 (en) * 1972-05-26 1973-12-13 Hoechst Ag BENZENE SULFONYL URUBE AND METHOD FOR MANUFACTURING IT
EP0101670B1 (en) * 1982-08-23 1988-03-09 Ciba-Geigy Ag Process for the preparation of herbicides and plant growth regulating sulfonyl ureas

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1031088A (en) * 1964-04-16 1966-05-25 Hoechst Ag Benzenesulphonyl-ureas and process for their manufacture
AT262311B (en) * 1964-10-16 1968-06-10 Hoechst Ag Process for the preparation of new benzenesulfonylureas and their salts

Also Published As

Publication number Publication date
DE2021828A1 (en) 1970-11-19
DK128244B (en) 1974-03-25
DK128244C (en) 1981-02-23
NO130825C (en) 1975-02-19
CA954525A (en) 1974-09-10
ES391914A1 (en) 1973-07-01
ES391915A1 (en) 1973-07-01
ES391913A1 (en) 1973-07-01
FR2051513A1 (en) 1971-04-09
DE2021828B2 (en) 1974-02-21
ES379494A1 (en) 1973-12-01
SE374743B (en) 1975-03-17
NL7006726A (en) 1970-11-11
FI54476B (en) 1978-08-31
FR2051513B1 (en) 1974-06-14
IE34211L (en) 1970-11-09
NO130825B (en) 1974-11-11
CH557810A (en) 1975-01-15
FI54476C (en) 1978-12-11
JPS4945868B1 (en) 1974-12-06
DE2065185A1 (en) 1973-02-08
ES391916A1 (en) 1973-07-01
DE2021828C3 (en) 1981-12-10

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