IE40999B1 - Cyclohexenyl compounds - Google Patents
Cyclohexenyl compoundsInfo
- Publication number
- IE40999B1 IE40999B1 IE864/75A IE86475A IE40999B1 IE 40999 B1 IE40999 B1 IE 40999B1 IE 864/75 A IE864/75 A IE 864/75A IE 86475 A IE86475 A IE 86475A IE 40999 B1 IE40999 B1 IE 40999B1
- Authority
- IE
- Ireland
- Prior art keywords
- carbon atoms
- oxocyclohex
- formula
- image
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
3-Oxocyclohex-1-en-1-ylureas of the formula (I) <IMAGE> in which R1, R2 and R3 denote alkyl groups having 1 to 3 carbon atoms or alkenyl groups having 2 to 3 carbon atoms, where the total number of the carbon atoms of R1, R2 and R3 does not exceed five and two of the radicals R1, R2 and R3 can be bonded to one another to form a cycloalkyl or cycloalkenyl group, preferably 1-tert-butyl-3-(3-oxocyclohex-1-en-1-yl)urea, exhibit antihypertensive activity in mammals. The said compounds are obtained by reaction of a compound of the formula II <IMAGE> with 1,3-cyclohexanedione.
[GB1457245A]
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46169774A | 1974-04-17 | 1974-04-17 | |
US52544574A | 1974-11-20 | 1974-11-20 | |
US05/555,308 US4002767A (en) | 1974-11-20 | 1975-03-11 | 1-Tertiary-alkyl-3-(substituted cyclohexenyl)ureas as antihypertensive agents |
Publications (2)
Publication Number | Publication Date |
---|---|
IE40999L IE40999L (en) | 1975-10-17 |
IE40999B1 true IE40999B1 (en) | 1979-09-26 |
Family
ID=27412847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE864/75A IE40999B1 (en) | 1974-04-17 | 1975-04-17 | Cyclohexenyl compounds |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS50148337A (en) |
AR (1) | AR206020A1 (en) |
CA (1) | CA1051029A (en) |
CH (1) | CH611273A5 (en) |
DD (1) | DD119223A5 (en) |
DE (1) | DE2516556A1 (en) |
DK (1) | DK134318B (en) |
ES (1) | ES436647A1 (en) |
FI (1) | FI751127A (en) |
FR (1) | FR2267766B1 (en) |
GB (1) | GB1457245A (en) |
IE (1) | IE40999B1 (en) |
IL (1) | IL47097A (en) |
LU (1) | LU72305A1 (en) |
NL (1) | NL7504568A (en) |
NO (1) | NO751350L (en) |
PH (1) | PH11869A (en) |
SE (1) | SE398116B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54151218A (en) * | 1978-04-24 | 1979-11-28 | British Hovercraft Corp Ltd | Split preventive device |
EP0004959A1 (en) * | 1978-04-24 | 1979-10-31 | Ciba-Geigy Ag | Process for preparing 3-oxo-cyclopentenyl ureas, compounds thus obtained, pharmaceutical compositions containing them and 3-oxo-cyclopentenylisothio ureas |
ES2045177T3 (en) * | 1987-02-09 | 1994-01-16 | Ciba Geigy Ag | HERBICIDE AGENTS OR PLANTS GROWTH REGULATORS BASED ON NEW CYCLOHEXANODIONAS AND THEIR PREPARATION PROCEDURE. |
-
1975
- 1975-01-01 AR AR258395A patent/AR206020A1/en active
- 1975-03-26 SE SE7503522A patent/SE398116B/en not_active IP Right Cessation
- 1975-04-15 CA CA224,635A patent/CA1051029A/en not_active Expired
- 1975-04-15 IL IL47097A patent/IL47097A/en unknown
- 1975-04-16 FI FI751127A patent/FI751127A/fi not_active Application Discontinuation
- 1975-04-16 DK DK163975AA patent/DK134318B/en not_active IP Right Cessation
- 1975-04-16 PH PH17060A patent/PH11869A/en unknown
- 1975-04-16 DD DD185481A patent/DD119223A5/xx unknown
- 1975-04-16 FR FR7511794A patent/FR2267766B1/fr not_active Expired
- 1975-04-16 NO NO751350A patent/NO751350L/no unknown
- 1975-04-16 GB GB1567075A patent/GB1457245A/en not_active Expired
- 1975-04-16 DE DE19752516556 patent/DE2516556A1/en not_active Withdrawn
- 1975-04-16 ES ES436647A patent/ES436647A1/en not_active Expired
- 1975-04-17 JP JP50045923A patent/JPS50148337A/ja active Pending
- 1975-04-17 NL NL7504568A patent/NL7504568A/en not_active Application Discontinuation
- 1975-04-17 IE IE864/75A patent/IE40999B1/en unknown
- 1975-04-17 CH CH494775A patent/CH611273A5/en not_active IP Right Cessation
- 1975-04-17 LU LU72305A patent/LU72305A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NO751350L (en) | 1975-10-20 |
FI751127A (en) | 1975-10-18 |
LU72305A1 (en) | 1976-03-17 |
IE40999L (en) | 1975-10-17 |
AU8013475A (en) | 1976-10-21 |
DK134318C (en) | 1977-04-18 |
PH11869A (en) | 1978-08-04 |
GB1457245A (en) | 1976-12-01 |
DD119223A5 (en) | 1976-04-12 |
DK134318B (en) | 1976-10-18 |
IL47097A0 (en) | 1975-06-25 |
FR2267766B1 (en) | 1978-10-06 |
DE2516556A1 (en) | 1975-10-30 |
DK163975A (en) | 1975-10-18 |
CH611273A5 (en) | 1979-05-31 |
NL7504568A (en) | 1975-10-21 |
CA1051029A (en) | 1979-03-20 |
SE7503522L (en) | 1975-10-20 |
AR206020A1 (en) | 1976-06-23 |
JPS50148337A (en) | 1975-11-27 |
SE398116B (en) | 1977-12-05 |
FR2267766A1 (en) | 1975-11-14 |
ES436647A1 (en) | 1977-08-01 |
IL47097A (en) | 1978-03-10 |
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