SE398116B - ANALOGICAL PROCEDURE FOR THE PREPARATION OF CYCLOHEXENYL UCARBAMIDES - Google Patents
ANALOGICAL PROCEDURE FOR THE PREPARATION OF CYCLOHEXENYL UCARBAMIDESInfo
- Publication number
- SE398116B SE398116B SE7503522A SE7503522A SE398116B SE 398116 B SE398116 B SE 398116B SE 7503522 A SE7503522 A SE 7503522A SE 7503522 A SE7503522 A SE 7503522A SE 398116 B SE398116 B SE 398116B
- Authority
- SE
- Sweden
- Prior art keywords
- ucarbamides
- cyclohexenyl
- preparation
- carbon atoms
- oxocyclohex
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
3-Oxocyclohex-1-en-1-ylureas of the formula (I) <IMAGE> in which R1, R2 and R3 denote alkyl groups having 1 to 3 carbon atoms or alkenyl groups having 2 to 3 carbon atoms, where the total number of the carbon atoms of R1, R2 and R3 does not exceed five and two of the radicals R1, R2 and R3 can be bonded to one another to form a cycloalkyl or cycloalkenyl group, preferably 1-tert-butyl-3-(3-oxocyclohex-1-en-1-yl)urea, exhibit antihypertensive activity in mammals. The said compounds are obtained by reaction of a compound of the formula II <IMAGE> with 1,3-cyclohexanedione.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46169774A | 1974-04-17 | 1974-04-17 | |
US52544574A | 1974-11-20 | 1974-11-20 | |
US05/555,308 US4002767A (en) | 1974-11-20 | 1975-03-11 | 1-Tertiary-alkyl-3-(substituted cyclohexenyl)ureas as antihypertensive agents |
Publications (2)
Publication Number | Publication Date |
---|---|
SE7503522L SE7503522L (en) | 1975-10-20 |
SE398116B true SE398116B (en) | 1977-12-05 |
Family
ID=27412847
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7503522A SE398116B (en) | 1974-04-17 | 1975-03-26 | ANALOGICAL PROCEDURE FOR THE PREPARATION OF CYCLOHEXENYL UCARBAMIDES |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS50148337A (en) |
AR (1) | AR206020A1 (en) |
CA (1) | CA1051029A (en) |
CH (1) | CH611273A5 (en) |
DD (1) | DD119223A5 (en) |
DE (1) | DE2516556A1 (en) |
DK (1) | DK134318B (en) |
ES (1) | ES436647A1 (en) |
FI (1) | FI751127A (en) |
FR (1) | FR2267766B1 (en) |
GB (1) | GB1457245A (en) |
IE (1) | IE40999B1 (en) |
IL (1) | IL47097A (en) |
LU (1) | LU72305A1 (en) |
NL (1) | NL7504568A (en) |
NO (1) | NO751350L (en) |
PH (1) | PH11869A (en) |
SE (1) | SE398116B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0004959A1 (en) * | 1978-04-24 | 1979-10-31 | Ciba-Geigy Ag | Process for preparing 3-oxo-cyclopentenyl ureas, compounds thus obtained, pharmaceutical compositions containing them and 3-oxo-cyclopentenylisothio ureas |
JPS54151218A (en) * | 1978-04-24 | 1979-11-28 | British Hovercraft Corp Ltd | Split preventive device |
ATE63901T1 (en) * | 1987-02-09 | 1991-06-15 | Ciba Geigy Ag | NEW CYCLOHEXANDIONES. |
-
1975
- 1975-01-01 AR AR258395A patent/AR206020A1/en active
- 1975-03-26 SE SE7503522A patent/SE398116B/en not_active IP Right Cessation
- 1975-04-15 CA CA224,635A patent/CA1051029A/en not_active Expired
- 1975-04-15 IL IL47097A patent/IL47097A/en unknown
- 1975-04-16 DK DK163975AA patent/DK134318B/en not_active IP Right Cessation
- 1975-04-16 DD DD185481A patent/DD119223A5/xx unknown
- 1975-04-16 FI FI751127A patent/FI751127A/fi not_active Application Discontinuation
- 1975-04-16 PH PH17060A patent/PH11869A/en unknown
- 1975-04-16 NO NO751350A patent/NO751350L/no unknown
- 1975-04-16 DE DE19752516556 patent/DE2516556A1/en not_active Withdrawn
- 1975-04-16 FR FR7511794A patent/FR2267766B1/fr not_active Expired
- 1975-04-16 ES ES436647A patent/ES436647A1/en not_active Expired
- 1975-04-16 GB GB1567075A patent/GB1457245A/en not_active Expired
- 1975-04-17 CH CH494775A patent/CH611273A5/en not_active IP Right Cessation
- 1975-04-17 JP JP50045923A patent/JPS50148337A/ja active Pending
- 1975-04-17 IE IE864/75A patent/IE40999B1/en unknown
- 1975-04-17 NL NL7504568A patent/NL7504568A/en not_active Application Discontinuation
- 1975-04-17 LU LU72305A patent/LU72305A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DK134318C (en) | 1977-04-18 |
CA1051029A (en) | 1979-03-20 |
IE40999L (en) | 1975-10-17 |
SE7503522L (en) | 1975-10-20 |
CH611273A5 (en) | 1979-05-31 |
GB1457245A (en) | 1976-12-01 |
DE2516556A1 (en) | 1975-10-30 |
IL47097A (en) | 1978-03-10 |
JPS50148337A (en) | 1975-11-27 |
FI751127A (en) | 1975-10-18 |
LU72305A1 (en) | 1976-03-17 |
NO751350L (en) | 1975-10-20 |
AU8013475A (en) | 1976-10-21 |
DK134318B (en) | 1976-10-18 |
IE40999B1 (en) | 1979-09-26 |
DD119223A5 (en) | 1976-04-12 |
FR2267766B1 (en) | 1978-10-06 |
FR2267766A1 (en) | 1975-11-14 |
ES436647A1 (en) | 1977-08-01 |
NL7504568A (en) | 1975-10-21 |
IL47097A0 (en) | 1975-06-25 |
AR206020A1 (en) | 1976-06-23 |
PH11869A (en) | 1978-08-04 |
DK163975A (en) | 1975-10-18 |
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Legal Events
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NUG | Patent has lapsed |
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