IE32504B1 - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number
IE32504B1
IE32504B1 IE1425/68A IE142568A IE32504B1 IE 32504 B1 IE32504 B1 IE 32504B1 IE 1425/68 A IE1425/68 A IE 1425/68A IE 142568 A IE142568 A IE 142568A IE 32504 B1 IE32504 B1 IE 32504B1
Authority
IE
Ireland
Prior art keywords
alkyl
hal
benzodiazepine derivatives
phch2
subst
Prior art date
Application number
IE1425/68A
Other languages
English (en)
Other versions
IE32504L (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of IE32504L publication Critical patent/IE32504L/xx
Publication of IE32504B1 publication Critical patent/IE32504B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
IE1425/68A 1967-11-24 1968-11-22 Benzodiazepine derivatives IE32504B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1064767A AT280290B (de) 1967-11-24 1967-11-24 Verfahren zur Herstellung von neuen 1-Phenyl-4-alkyl-3H-1,4-benzodiazepin-2,5-[1H,4H]-dionen

Publications (2)

Publication Number Publication Date
IE32504L IE32504L (en) 1969-05-24
IE32504B1 true IE32504B1 (en) 1973-08-22

Family

ID=3623762

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1425/68A IE32504B1 (en) 1967-11-24 1968-11-22 Benzodiazepine derivatives

Country Status (13)

Country Link
AT (1) AT280290B (es)
BE (1) BE724364A (es)
BR (1) BR6804236D0 (es)
CH (1) CH523265A (es)
DE (1) DE1810423B2 (es)
DK (1) DK124950B (es)
ES (2) ES360410A1 (es)
FR (2) FR1593335A (es)
GB (1) GB1173540A (es)
IE (1) IE32504B1 (es)
IL (1) IL31146A (es)
NL (1) NL6815755A (es)
SE (1) SE356979B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3914216A (en) * 1962-12-18 1975-10-21 Boehringer Sohn Ingelheim 1-Phenyl-3H-1,4-benzodiazepine-2,5-(1H,4H)-diones
DE2117438A1 (de) * 1971-04-08 1972-10-19 CH. Boehringer Sohn, 6507 Ingelheim Neue substituiert 1,3-Dihydro-2H-1 ^-benzodiazepine^-one
BE793460A (fr) * 1971-12-29 1973-06-28 Boehringer Sohn Ingelheim Nouvelles 1-aryl-3h,1,4-benzodiazepine-2,5-(1h
US7125866B1 (en) 1999-04-30 2006-10-24 Regents Of The University Of Michigan Therapeutic applications of pro-apoptotic benzodiazepines
US7276348B2 (en) 1999-04-30 2007-10-02 Regents Of The University Of Michigan Compositions and methods relating to F1F0-ATPase inhibitors and targets thereof
US20060025388A1 (en) 1999-04-30 2006-02-02 Glick Gary D Compositions and methods relating to novel compounds and targets thereof
US7572788B2 (en) 1999-04-30 2009-08-11 The Regents Of The University Of Michigan Compositions and methods relating to novel compounds and targets thereof
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
US7638624B2 (en) 2005-01-03 2009-12-29 The Regents Of The University Of Michigan Compositions and methods relating to novel benzodiazepine compounds and derivatives
US20070043033A1 (en) 2005-06-01 2007-02-22 The Regents Of The University Of Michigan Unsolvated benzodiazepine compositions and methods
EP2604269B1 (en) 2005-11-01 2014-09-24 The Regents Of The University Of Michigan 1,4-benzodiazepine-2,5-diones with therapeutic properties
US7759338B2 (en) 2006-04-27 2010-07-20 The Regents Of The University Of Michigan Soluble 1,4 benzodiazepine compounds and stable salts thereof
NZ573452A (en) 2006-06-09 2011-09-30 Univ Michigan Compositions and methods relating to novel compounds and targets thereof
NZ579507A (en) 2007-03-09 2011-11-25 Univ Michigan Compositions and methods relating to novel compounds and targets thereof
JP2010526825A (ja) 2007-05-10 2010-08-05 エーエムアール テクノロジー インコーポレイテッド アリール置換およびヘテロアリール置換テトラヒドロベンゾ−１，４−ジアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
AU2008298870C1 (en) 2007-09-14 2014-10-09 The Regents Of The University Of Michigan F1F0-ATPase inhibitors and related methods
CN101918375A (zh) 2007-11-06 2010-12-15 密歇根大学董事会 在皮肤病症的治疗中有用的苯并二氮杂*酮化合物
US8497307B2 (en) 2008-09-11 2013-07-30 The Regents Of The University Of Michigan Aryl guanidine F1F0-ATPase inhibitors and related methods
WO2010121164A2 (en) 2009-04-17 2010-10-21 The Regents Of The University Of Michigan 1,4-benzodiazepinone compounds and their use in treating cancer
EP2470020A4 (en) 2009-09-18 2013-03-13 Univ Michigan BENZODIAZEPINONE COMPOUNDS AND TREATMENT METHODS THEREWITH
CN102753544A (zh) 2009-11-17 2012-10-24 密执安大学评议会 具有治疗性能的1，4-苯并二氮杂*-2，5-二酮和相关化合物
JP5856063B2 (ja) 2009-11-17 2016-02-09 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 治療特性を有する１，４−ベンゾジアゼピン−２，５−ジオンおよび関連化合物
EP3043790B1 (en) 2013-09-11 2021-05-26 The Administrators of the Tulane Educational Fund Novel anthranilic amides and the use thereof

Also Published As

Publication number Publication date
BE724364A (es) 1969-05-22
DE1810423A1 (de) 1969-10-09
GB1173540A (en) 1969-12-10
DK124950B (da) 1972-12-11
IE32504L (en) 1969-05-24
AT280290B (de) 1970-04-10
FR1593335A (es) 1970-05-25
FR8310M (es) 1970-11-23
BR6804236D0 (pt) 1973-02-08
DE1810423C3 (es) 1973-10-11
SE356979B (es) 1973-06-12
IL31146A (en) 1972-04-27
ES378977A1 (es) 1973-01-16
DE1810423B2 (de) 1973-03-22
NL6815755A (es) 1969-05-28
CH523265A (de) 1972-05-31
IL31146A0 (en) 1969-01-29
ES360410A1 (es) 1970-11-01

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