IE31971B1 - Ophthalmic compositions - Google Patents
Ophthalmic compositionsInfo
- Publication number
- IE31971B1 IE31971B1 IE249/68A IE24968A IE31971B1 IE 31971 B1 IE31971 B1 IE 31971B1 IE 249/68 A IE249/68 A IE 249/68A IE 24968 A IE24968 A IE 24968A IE 31971 B1 IE31971 B1 IE 31971B1
- Authority
- IE
- Ireland
- Prior art keywords
- topical ophthalmic
- cycloheptene
- dibenzo
- dihydro
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000000699 topical effect Effects 0.000 abstract 3
- JWZZKOKVBUJMES-UHFFFAOYSA-N (+-)-Isoprenaline Chemical compound CC(C)NCC(O)C1=CC=C(O)C(O)=C1 JWZZKOKVBUJMES-UHFFFAOYSA-N 0.000 abstract 1
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract 1
- UOKCFJSKJHPUDQ-PWCSWUJKSA-N (8R,9R)-1-[3-(methylamino)propyl]-16-oxatetracyclo[7.6.1.02,7.010,15]hexadeca-2,4,6,10,12,14-hexaen-8-ol Chemical compound O1C2(C3=C([C@@H]1[C@@H](C1=C2C=CC=C1)O)C=CC=C3)CCCNC UOKCFJSKJHPUDQ-PWCSWUJKSA-N 0.000 abstract 1
- UCTWMZQNUQWSLP-VIFPVBQESA-N (R)-adrenaline Chemical compound CNC[C@H](O)C1=CC=C(O)C(O)=C1 UCTWMZQNUQWSLP-VIFPVBQESA-N 0.000 abstract 1
- 229930182837 (R)-adrenaline Natural products 0.000 abstract 1
- JCIIKRHCWVHVFF-UHFFFAOYSA-N 1,2,4-thiadiazol-5-amine;hydrochloride Chemical compound Cl.NC1=NC=NS1 JCIIKRHCWVHVFF-UHFFFAOYSA-N 0.000 abstract 1
- FWWOWPGPERBCNJ-UHFFFAOYSA-N 2-hydroxy-4-(2-hydroxyethoxy)-4-oxobutanoic acid Chemical compound OCCOC(=O)CC(O)C(O)=O FWWOWPGPERBCNJ-UHFFFAOYSA-N 0.000 abstract 1
- GBEPCNLTEZAPMJ-UHFFFAOYSA-N 8-hydroxy-1h-quinolin-2-one;sulfuric acid Chemical compound OS(O)(=O)=O.C1=CC=C(O)C2=NC(O)=CC=C21 GBEPCNLTEZAPMJ-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- QAJBMPFDGJGKRN-UHFFFAOYSA-N N-[1-[3-(dimethylamino)propyl]-16-oxatetracyclo[7.6.1.02,7.010,15]hexadeca-2,4,6,10,12,14-hexaen-8-ylidene]hydroxylamine Chemical compound CN(CCCC12C3=C(C(C(C4=C1C=CC=C4)=NO)O2)C=CC=C3)C QAJBMPFDGJGKRN-UHFFFAOYSA-N 0.000 abstract 1
- DWAQJAXMDSEUJJ-UHFFFAOYSA-M Sodium bisulfite Chemical compound [Na+].OS([O-])=O DWAQJAXMDSEUJJ-UHFFFAOYSA-M 0.000 abstract 1
- 239000000150 Sympathomimetic Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000001384 anti-glaucoma Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229910021538 borax Inorganic materials 0.000 abstract 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 abstract 1
- 239000004327 boric acid Substances 0.000 abstract 1
- 229960005139 epinephrine Drugs 0.000 abstract 1
- 239000003885 eye ointment Substances 0.000 abstract 1
- 229940039009 isoproterenol Drugs 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 229960002748 norepinephrine Drugs 0.000 abstract 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract 1
- 229940069265 ophthalmic ointment Drugs 0.000 abstract 1
- 229940096826 phenylmercuric acetate Drugs 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 abstract 1
- 239000004289 sodium hydrogen sulphite Substances 0.000 abstract 1
- 235000010339 sodium tetraborate Nutrition 0.000 abstract 1
- 230000001975 sympathomimetic effect Effects 0.000 abstract 1
- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62354067A | 1967-03-16 | 1967-03-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE31971L IE31971L (en) | 1968-09-16 |
| IE31971B1 true IE31971B1 (en) | 1973-03-07 |
Family
ID=24498471
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE249/68A IE31971B1 (en) | 1967-03-16 | 1968-03-04 | Ophthalmic compositions |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3467756A (en:Method) |
| BE (1) | BE712259A (en:Method) |
| DE (1) | DE1667898A1 (en:Method) |
| FR (1) | FR7841M (en:Method) |
| GB (1) | GB1174882A (en:Method) |
| IE (1) | IE31971B1 (en:Method) |
| IL (1) | IL29570A (en:Method) |
| NL (1) | NL6802823A (en:Method) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716952A (en) * | 1992-03-18 | 1998-02-10 | Allergan | Method for reducing intraocular pressure in the mammalian eye by administration of muscarinic antagonists |
| US6077839A (en) | 1992-03-19 | 2000-06-20 | Allergan Sales, Inc. | Method for reducing intraocular pressure in the mammalian eye by administration of gamma aminobutyric acid (GABA) agonists |
| AU2829395A (en) * | 1994-06-16 | 1996-01-05 | Allergan, Inc. | Method for reducing intraocular pressure in the mammalian eye by administration of calcium chelators |
| US6350780B1 (en) | 1995-07-28 | 2002-02-26 | Allergan Sales, Inc. | Methods and compositions for drug delivery |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3264342A (en) * | 1963-05-24 | 1966-08-02 | Geigy Chem Corp | Derivatives of 5h-dibenzo[a, d] cycloheptene |
| US3336340A (en) * | 1963-11-29 | 1967-08-15 | Rohm & Haas | Benzopyrans and process for the preparation thereof |
-
1967
- 1967-03-16 US US623540A patent/US3467756A/en not_active Expired - Lifetime
-
1968
- 1968-02-28 NL NL6802823A patent/NL6802823A/xx unknown
- 1968-03-04 IL IL29570A patent/IL29570A/en unknown
- 1968-03-04 IE IE249/68A patent/IE31971B1/xx unknown
- 1968-03-12 GB GB01980/68A patent/GB1174882A/en not_active Expired
- 1968-03-15 DE DE19681667898 patent/DE1667898A1/de active Pending
- 1968-03-15 BE BE712259D patent/BE712259A/xx unknown
- 1968-03-15 FR FR144115A patent/FR7841M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6802823A (en:Method) | 1968-09-17 |
| GB1174882A (en) | 1969-12-17 |
| US3467756A (en) | 1969-09-16 |
| IE31971L (en) | 1968-09-16 |
| DE1667898A1 (de) | 1971-07-22 |
| BE712259A (en:Method) | 1968-09-16 |
| FR7841M (en:Method) | 1970-05-25 |
| IL29570A (en) | 1971-07-28 |
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