IE31971B1 - Ophthalmic compositions - Google Patents

Ophthalmic compositions

Info

Publication number
IE31971B1
IE31971B1 IE249/68A IE24968A IE31971B1 IE 31971 B1 IE31971 B1 IE 31971B1 IE 249/68 A IE249/68 A IE 249/68A IE 24968 A IE24968 A IE 24968A IE 31971 B1 IE31971 B1 IE 31971B1
Authority
IE
Ireland
Prior art keywords
topical ophthalmic
cycloheptene
dibenzo
dihydro
compositions
Prior art date
Application number
IE249/68A
Other versions
IE31971L (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IE31971L publication Critical patent/IE31971L/en
Publication of IE31971B1 publication Critical patent/IE31971B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

1,174,882. Ophthalmic compositions. MERCK & CO. Inc. 12 March, 1968 [16 March, 1967], No. 11980/68 Heading ASB. An anti-glaucoma topical ophthalmic composition comprises 10, 11-dihydro-5-(3-dimethylaminopropyl)-5, 10-epoxy-11-hydroxyimino- 5H-dibenzo [a, d]-cycloheptene or trans 10, 11- dihydro-5-(3-methylaminopropyl)-5, 10-epoxy- 11-hydroxy-5H-dibenzo [a, d] cycloheptene, or their non-toxic acid addition salts (e.g. hydrochloride or hydrogen maleate), together with a conventional topical ophthalmic ointment or a topical ophthalmic buffered isotonic aqueous solution containing a preservative. The compositions may also contain an exogenous sympathomimetic amine (e.g. epinephrine, norepinephrine or isoproterenol), 8-hydroxyquinolone sulphate, sodium bisulphite, phenylmercuric acetate and boric acid and/or sodium borate. [GB1174882A]
IE249/68A 1967-03-16 1968-03-04 Ophthalmic compositions IE31971B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62354067A 1967-03-16 1967-03-16

Publications (2)

Publication Number Publication Date
IE31971L IE31971L (en) 1968-09-16
IE31971B1 true IE31971B1 (en) 1973-03-07

Family

ID=24498471

Family Applications (1)

Application Number Title Priority Date Filing Date
IE249/68A IE31971B1 (en) 1967-03-16 1968-03-04 Ophthalmic compositions

Country Status (8)

Country Link
US (1) US3467756A (en)
BE (1) BE712259A (en)
DE (1) DE1667898A1 (en)
FR (1) FR7841M (en)
GB (1) GB1174882A (en)
IE (1) IE31971B1 (en)
IL (1) IL29570A (en)
NL (1) NL6802823A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716952A (en) * 1992-03-18 1998-02-10 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of muscarinic antagonists
US6077839A (en) * 1992-03-19 2000-06-20 Allergan Sales, Inc. Method for reducing intraocular pressure in the mammalian eye by administration of gamma aminobutyric acid (GABA) agonists
WO1995034302A2 (en) * 1994-06-16 1995-12-21 Allergan Method for reducing intraocular pressure in the mammalian eye by administration of calcium chelators
US6350780B1 (en) 1995-07-28 2002-02-26 Allergan Sales, Inc. Methods and compositions for drug delivery

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3264342A (en) * 1963-05-24 1966-08-02 Geigy Chem Corp Derivatives of 5h-dibenzo[a, d] cycloheptene
US3336340A (en) * 1963-11-29 1967-08-15 Rohm & Haas Benzopyrans and process for the preparation thereof

Also Published As

Publication number Publication date
IE31971L (en) 1968-09-16
BE712259A (en) 1968-09-16
DE1667898A1 (en) 1971-07-22
IL29570A (en) 1971-07-28
US3467756A (en) 1969-09-16
FR7841M (en) 1970-05-25
GB1174882A (en) 1969-12-17
NL6802823A (en) 1968-09-17

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