ID29025A - Fenilalkenoilguanidina-fenilalkenoilguanidina yang disubstitusi asam empedu, proses pembuatannya, penggunaannya sebagai obat atau diaknostik dan obat-obat yang mengandungnya - Google Patents
Fenilalkenoilguanidina-fenilalkenoilguanidina yang disubstitusi asam empedu, proses pembuatannya, penggunaannya sebagai obat atau diaknostik dan obat-obat yang mengandungnyaInfo
- Publication number
- ID29025A ID29025A IDW00200100935A ID20010935A ID29025A ID 29025 A ID29025 A ID 29025A ID W00200100935 A IDW00200100935 A ID W00200100935A ID 20010935 A ID20010935 A ID 20010935A ID 29025 A ID29025 A ID 29025A
- Authority
- ID
- Indonesia
- Prior art keywords
- substituted
- processes
- fenilalkenoilguanidina
- empeduic
- annnostic
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title 2
- 239000002253 acid Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 201000001883 cholelithiasis Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000001130 gallstones Diseases 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
- C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19849722A DE19849722A1 (de) | 1998-10-28 | 1998-10-28 | Substituierte Phenyl-alkenoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID29025A true ID29025A (id) | 2001-07-26 |
Family
ID=7885948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW00200100935A ID29025A (id) | 1998-10-28 | 1999-10-15 | Fenilalkenoilguanidina-fenilalkenoilguanidina yang disubstitusi asam empedu, proses pembuatannya, penggunaannya sebagai obat atau diaknostik dan obat-obat yang mengandungnya |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6166002A (enExample) |
| EP (1) | EP1124841B1 (enExample) |
| JP (1) | JP4616479B2 (enExample) |
| KR (1) | KR20010085973A (enExample) |
| CN (1) | CN1325403A (enExample) |
| AT (1) | ATE236191T1 (enExample) |
| AU (1) | AU757365B2 (enExample) |
| BR (1) | BR9914929A (enExample) |
| CA (1) | CA2349523A1 (enExample) |
| CZ (1) | CZ20011429A3 (enExample) |
| DE (2) | DE19849722A1 (enExample) |
| DK (1) | DK1124841T3 (enExample) |
| ES (1) | ES2191466T3 (enExample) |
| HK (1) | HK1041271A1 (enExample) |
| HU (1) | HUP0103751A3 (enExample) |
| ID (1) | ID29025A (enExample) |
| PL (1) | PL348108A1 (enExample) |
| PT (1) | PT1124841E (enExample) |
| RU (1) | RU2232769C2 (enExample) |
| TR (1) | TR200101163T2 (enExample) |
| WO (1) | WO2000024761A1 (enExample) |
| ZA (1) | ZA200103106B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19941764A1 (de) | 1999-09-02 | 2001-03-15 | Aventis Pharma Gmbh | Substituierte Acylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikamente oder Diagnostika sowie sie enthaltende Medikamente |
| EP1646371A4 (en) | 2003-06-26 | 2010-09-22 | Biotron Ltd | ANTIVIRAL COMPOSITIONS AND METHODS |
| DE10338554A1 (de) * | 2003-08-22 | 2005-03-31 | Aventis Pharma Deutschland Gmbh | Pentafluorosulfanylphenyl-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| US7390837B2 (en) | 2004-01-30 | 2008-06-24 | Ethicon, Inc. | Germicidal compositions containing phenylmalonaldehyde-type compounds, or mixtures of phenylmalonaldehyde-type compounds and phthalaldehydes, and methods of using such compositions for disinfection or sterilization |
| US6891069B1 (en) | 2004-01-30 | 2005-05-10 | Ethicon, Inc. | Synthesis of 4-substituted phthalaldehyde |
| US20050171215A1 (en) * | 2004-01-30 | 2005-08-04 | Ethicon, Inc. | Germicidal compositions containing halogenated phthalaldehyes, and methods of using such compositions for disinfection or sterilization |
| US7476767B2 (en) | 2004-01-30 | 2009-01-13 | Ethicon, Inc. | Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds or compositions for disinfection or sterilization |
| US7291649B2 (en) | 2005-06-29 | 2007-11-06 | Ethicon, Inc. | Forming germicidal aromatic dialdehydes with acetals |
| CZ301037B6 (cs) * | 2007-09-06 | 2009-10-21 | Vysoká škola chemicko-technologická v Praze | Amidové konjugáty steroidních a žlucových kyselin s D-glukosaminem a zpusob jejich prípravy |
| EP3351248B1 (en) | 2008-12-31 | 2021-06-09 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| KR102287207B1 (ko) | 2013-04-12 | 2021-08-09 | 알데릭스, 인코포레이티드 | Nhe3-결합 화합물 및 포스페이트 수송을 저해하는 방법 |
| JP2020505333A (ja) | 2017-01-09 | 2020-02-20 | アルデリックス, インコーポレイテッド | Nhe媒介性アンチポートの阻害薬 |
| CN110267944B (zh) | 2017-01-09 | 2024-03-08 | 阿德利克斯股份有限公司 | 可用于治疗胃肠道病症的化合物 |
| WO2020041673A1 (en) | 2018-08-23 | 2020-02-27 | President And Fellows Of Harvard College | Compositions and methods related to cholic acid-7-sulfate as a treatment for diabetes |
| US12419897B2 (en) | 2018-12-04 | 2025-09-23 | President And Fellows Of Harvard College | Synthetic derivatives of cholic acid 7-sulfate and uses thereof |
| EP3972599B1 (en) | 2019-05-21 | 2025-10-22 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW289021B (enExample) * | 1993-05-08 | 1996-10-21 | Hoechst Ag | |
| US5792635A (en) * | 1995-06-07 | 1998-08-11 | Magainin Pharmaceuticals, Inc. | Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine |
| JPH0959162A (ja) * | 1995-08-28 | 1997-03-04 | Makoto Takahashi | 胆石溶解剤 |
| DE19633966A1 (de) * | 1996-08-22 | 1998-02-26 | Hoechst Ag | Phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
-
1998
- 1998-10-28 DE DE19849722A patent/DE19849722A1/de not_active Withdrawn
-
1999
- 1999-10-15 HK HK02102812.0A patent/HK1041271A1/zh unknown
- 1999-10-15 CN CN99812751A patent/CN1325403A/zh active Pending
- 1999-10-15 JP JP2000578331A patent/JP4616479B2/ja not_active Expired - Fee Related
- 1999-10-15 DE DE59904875T patent/DE59904875D1/de not_active Expired - Lifetime
- 1999-10-15 HU HU0103751A patent/HUP0103751A3/hu unknown
- 1999-10-15 AU AU62032/99A patent/AU757365B2/en not_active Ceased
- 1999-10-15 PT PT99949001T patent/PT1124841E/pt unknown
- 1999-10-15 BR BR9914929-0A patent/BR9914929A/pt not_active IP Right Cessation
- 1999-10-15 ID IDW00200100935A patent/ID29025A/id unknown
- 1999-10-15 DK DK99949001T patent/DK1124841T3/da active
- 1999-10-15 CZ CZ20011429A patent/CZ20011429A3/cs unknown
- 1999-10-15 KR KR1020017005343A patent/KR20010085973A/ko not_active Abandoned
- 1999-10-15 PL PL99348108A patent/PL348108A1/xx unknown
- 1999-10-15 WO PCT/EP1999/007828 patent/WO2000024761A1/de not_active Ceased
- 1999-10-15 RU RU2001114207/04A patent/RU2232769C2/ru not_active IP Right Cessation
- 1999-10-15 AT AT99949001T patent/ATE236191T1/de not_active IP Right Cessation
- 1999-10-15 EP EP99949001A patent/EP1124841B1/de not_active Expired - Lifetime
- 1999-10-15 TR TR2001/01163T patent/TR200101163T2/xx unknown
- 1999-10-15 ES ES99949001T patent/ES2191466T3/es not_active Expired - Lifetime
- 1999-10-15 CA CA002349523A patent/CA2349523A1/en not_active Abandoned
- 1999-10-20 US US09/422,146 patent/US6166002A/en not_active Expired - Lifetime
-
2001
- 2001-04-17 ZA ZA200103106A patent/ZA200103106B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE59904875D1 (de) | 2003-05-08 |
| ATE236191T1 (de) | 2003-04-15 |
| WO2000024761A1 (de) | 2000-05-04 |
| CN1325403A (zh) | 2001-12-05 |
| AU6203299A (en) | 2000-05-15 |
| US6166002A (en) | 2000-12-26 |
| ZA200103106B (en) | 2002-08-28 |
| HUP0103751A3 (en) | 2002-12-28 |
| DK1124841T3 (da) | 2003-07-28 |
| EP1124841B1 (de) | 2003-04-02 |
| RU2232769C2 (ru) | 2004-07-20 |
| BR9914929A (pt) | 2001-07-10 |
| JP2002528460A (ja) | 2002-09-03 |
| AU757365B2 (en) | 2003-02-20 |
| HUP0103751A2 (hu) | 2002-04-29 |
| HK1041271A1 (zh) | 2002-07-05 |
| TR200101163T2 (tr) | 2001-08-21 |
| ES2191466T3 (es) | 2003-09-01 |
| KR20010085973A (ko) | 2001-09-07 |
| PL348108A1 (en) | 2002-05-06 |
| CZ20011429A3 (cs) | 2001-08-15 |
| JP4616479B2 (ja) | 2011-01-19 |
| DE19849722A1 (de) | 2000-05-04 |
| CA2349523A1 (en) | 2000-05-04 |
| EP1124841A1 (de) | 2001-08-22 |
| PT1124841E (pt) | 2003-08-29 |
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