ID28032A - TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2 - Google Patents

TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2

Info

Publication number
ID28032A
ID28032A IDW20010780A ID20010780A ID28032A ID 28032 A ID28032 A ID 28032A ID W20010780 A IDW20010780 A ID W20010780A ID 20010780 A ID20010780 A ID 20010780A ID 28032 A ID28032 A ID 28032A
Authority
ID
Indonesia
Prior art keywords
triciclic
antagonis
piperidin
Prior art date
Application number
IDW20010780A
Other languages
English (en)
Indonesian (id)
Inventor
Ludo E J Kennis
Frans M A Van Den Keybus
Josephus C Mertens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ID28032A publication Critical patent/ID28032A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
IDW20010780A 1998-10-06 1999-10-01 TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2 ID28032A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98203370 1998-10-06

Publications (1)

Publication Number Publication Date
ID28032A true ID28032A (id) 2001-05-03

Family

ID=8234191

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20010780A ID28032A (id) 1998-10-06 1999-10-01 TRISIKLIK PIPERIDIN-Δ3-SEBAGAI ANTAGONIS-α2

Country Status (31)

Country Link
US (1) US6495555B1 (fr)
EP (1) EP1119571B1 (fr)
JP (1) JP4590101B2 (fr)
KR (1) KR20010071843A (fr)
CN (1) CN1131230C (fr)
AR (1) AR024216A1 (fr)
AT (1) ATE232869T1 (fr)
AU (1) AU760502B2 (fr)
BG (1) BG64872B1 (fr)
BR (1) BR9913507A (fr)
CA (1) CA2345622C (fr)
CZ (1) CZ20011104A3 (fr)
DE (1) DE69905478T2 (fr)
DK (1) DK1119571T3 (fr)
EE (1) EE04770B1 (fr)
ES (1) ES2193751T3 (fr)
HK (1) HK1038010A1 (fr)
HU (1) HUP0104002A3 (fr)
ID (1) ID28032A (fr)
IL (1) IL142443A0 (fr)
NO (1) NO20011270L (fr)
NZ (1) NZ510115A (fr)
PL (1) PL347894A1 (fr)
PT (1) PT1119571E (fr)
RU (1) RU2230744C2 (fr)
SI (1) SI1119571T1 (fr)
SK (1) SK285585B6 (fr)
TR (1) TR200100952T2 (fr)
TW (1) TWI248441B (fr)
UA (1) UA69420C2 (fr)
WO (1) WO2000020421A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK285386B6 (sk) * 1998-10-06 2006-12-07 Janssen Pharmaceutica N. V. Tricyklické delta3-piperidíny ako farmaceutiká a spôsob ich prípravy
WO2003082825A1 (fr) * 2002-04-03 2003-10-09 Orion Corporation Utilisation de l'antagoniste d'un alfa2-adrenocepteur en cas de maladies du snc
MXPA06011777A (es) 2004-04-12 2007-01-16 Taisho Pharma Co Ltd Compuesto de amina ciclico.
US20060035939A1 (en) * 2004-07-14 2006-02-16 Japan Tobacco Inc. 3-Aminobenzamide compounds and inhibitors of vanilloid receptor subtype 1 (VR1) activity
RU2392278C2 (ru) * 2004-07-15 2010-06-20 Джапан Тобакко Инк. Конденсированное производное бензамида и ингибитор активности подтипа 1 рецептора ваниллоида (vr1)
US7906508B2 (en) * 2005-12-28 2011-03-15 Japan Tobacco Inc. 3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity
NZ596137A (en) 2009-05-14 2013-08-30 Janssen Pharmaceutica Nv Compounds with two fused bicyclic heteroaryl moieties as modulators of leukotriene a4 hydrolase
JP2017503778A (ja) 2013-12-19 2017-02-02 バイエル ファーマ アクチエンゲゼルシャフト アドレナリン受容体α2C拮抗薬としての置換されたビピペリジニル誘導体
CN105980374A (zh) 2013-12-19 2016-09-28 拜耳制药股份公司 取代的哌啶基四氢喹啉
JOP20200052A1 (ar) 2013-12-19 2017-06-16 Bayer Pharma AG بيبريدينيل تتراهيدرو كوينولينات مستبدلة واستخدامها كمعضدات مستقبل أدريني ألفا- 2c
CN114276359B (zh) * 2022-01-05 2023-05-05 浙江大学 一种1,2,3,4-四氢苯并[4,5]呋喃[2,3-c]吡啶衍生物的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522959A1 (de) * 1985-06-27 1987-01-08 Merck Patent Gmbh Indolderivate
US4673680A (en) * 1985-09-18 1987-06-16 Pendleton Robert G α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
EP0339959A3 (fr) * 1988-04-27 1991-03-20 Glaxo Group Limited Dérivés de lactame
US4971974A (en) * 1988-06-16 1990-11-20 Neurex Corporation Benzothiophenes as appetite suppressants
US5100891A (en) * 1991-01-18 1992-03-31 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[B]indoles and related compounds
WO1998024791A1 (fr) * 1996-12-06 1998-06-11 Abbott Laboratories Composes alpha-1 adrenergiques a base de benzopyranopyrrole et de benzopyranopyridine
JP4459437B2 (ja) 1997-12-25 2010-04-28 明治製菓株式会社 テトラヒドロベンズインドール誘導体
SK285386B6 (sk) * 1998-10-06 2006-12-07 Janssen Pharmaceutica N. V. Tricyklické delta3-piperidíny ako farmaceutiká a spôsob ich prípravy

Also Published As

Publication number Publication date
WO2000020421A2 (fr) 2000-04-13
DE69905478D1 (de) 2003-03-27
EP1119571A2 (fr) 2001-08-01
CN1332744A (zh) 2002-01-23
CZ20011104A3 (cs) 2001-12-12
EE200100209A (et) 2002-06-17
HUP0104002A2 (hu) 2002-03-28
NO20011270D0 (no) 2001-03-13
EP1119571B1 (fr) 2003-02-19
SK285585B6 (sk) 2007-04-05
RU2230744C2 (ru) 2004-06-20
UA69420C2 (uk) 2004-09-15
PT1119571E (pt) 2003-06-30
SI1119571T1 (en) 2003-08-31
BG64872B1 (bg) 2006-07-31
AU6334199A (en) 2000-04-26
NO20011270L (no) 2001-03-13
JP2002526545A (ja) 2002-08-20
HUP0104002A3 (en) 2003-12-29
HK1038010A1 (en) 2002-03-01
DK1119571T3 (da) 2003-05-26
IL142443A0 (en) 2002-03-10
JP4590101B2 (ja) 2010-12-01
CN1131230C (zh) 2003-12-17
AR024216A1 (es) 2002-09-25
TR200100952T2 (tr) 2001-10-22
EE04770B1 (et) 2007-02-15
DE69905478T2 (de) 2004-03-18
KR20010071843A (ko) 2001-07-31
CA2345622C (fr) 2007-12-04
ATE232869T1 (de) 2003-03-15
US6495555B1 (en) 2002-12-17
PL347894A1 (en) 2002-04-22
AU760502B2 (en) 2003-05-15
NZ510115A (en) 2002-11-26
BG105332A (en) 2001-11-30
BR9913507A (pt) 2001-06-05
TWI248441B (en) 2006-02-01
SK4322001A3 (en) 2002-01-07
WO2000020421A3 (fr) 2000-08-03
CA2345622A1 (fr) 2000-04-13
ES2193751T3 (es) 2003-11-01

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