ID26230A - Turunan-turunan deoksiantrasiantrasiklin-13 dan proses untuk pembuatannya - Google Patents

Turunan-turunan deoksiantrasiantrasiklin-13 dan proses untuk pembuatannya

Info

Publication number
ID26230A
ID26230A IDW20000490A ID20000490A ID26230A ID 26230 A ID26230 A ID 26230A ID W20000490 A IDW20000490 A ID W20000490A ID 20000490 A ID20000490 A ID 20000490A ID 26230 A ID26230 A ID 26230A
Authority
ID
Indonesia
Prior art keywords
deocsiantrationantrasiklin
decreases
making
Prior art date
Application number
IDW20000490A
Other languages
English (en)
Indonesian (id)
Inventor
Xini Zhang
Richard D Olson
Gerald M Walsh
Original Assignee
Gem Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gem Pharmaceuticals Inc filed Critical Gem Pharmaceuticals Inc
Publication of ID26230A publication Critical patent/ID26230A/id

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IDW20000490A 1997-08-13 1998-08-13 Turunan-turunan deoksiantrasiantrasiklin-13 dan proses untuk pembuatannya ID26230A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/910,218 US5948896A (en) 1997-08-13 1997-08-13 Processes for preparing 13-deoxy anthracycline derivatives

Publications (1)

Publication Number Publication Date
ID26230A true ID26230A (id) 2000-12-07

Family

ID=25428480

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20000490A ID26230A (id) 1997-08-13 1998-08-13 Turunan-turunan deoksiantrasiantrasiklin-13 dan proses untuk pembuatannya

Country Status (15)

Country Link
US (1) US5948896A (cs)
EP (2) EP1600161A3 (cs)
JP (2) JP4603684B2 (cs)
KR (1) KR100516105B1 (cs)
CN (1) CN1154499C (cs)
AU (1) AU739033B2 (cs)
BR (1) BR9811147B1 (cs)
CA (1) CA2297149C (cs)
CZ (1) CZ302124B6 (cs)
HU (1) HUP0002717A3 (cs)
ID (1) ID26230A (cs)
IL (2) IL134494A0 (cs)
NZ (1) NZ502247A (cs)
RU (1) RU2233165C2 (cs)
WO (1) WO1999008687A1 (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them
AU2012211397B2 (en) * 2004-11-08 2015-09-17 Gem Pharmaceuticals, Llc Compositions and Processes for Preparing 13-Deoxy-Anthracyclines
US7244829B2 (en) * 2004-11-08 2007-07-17 Gem Pharmaceuticals, Llc Compositions and processes for preparing 13-deoxy-anthracyclines
US7776832B2 (en) 2006-04-21 2010-08-17 Gem Pharmaceuticals, Llc Anticancer treatment with a combination of taxanes and 13-deoxyanthracyclines
US10450340B2 (en) 2017-02-16 2019-10-22 Monopar Therapeutics Inc. 3′-deamino-3′-(2″-pyrroline-1″-yl)-5-imino-13-deoxyanthracyclines and methods of preparation

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1527892A (fr) * 1967-03-15 1968-06-07 Rhone Poulenc Sa Nouveau procédé de préparation de l'antibiotique 13057 r.p.
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
US4088569A (en) * 1976-02-24 1978-05-09 Uop Inc. Mercaptan oxidation in a liquid hydrocarbon with a metal phthalocyanine catalyst
US4134903A (en) * 1976-08-07 1979-01-16 Societa Farmaceutici Italia S.P.A. Anthracycline ethers and their preparation
US4411834A (en) * 1978-02-09 1983-10-25 Farmitalia Carlo Erba, S.P.A. Preparation of II-deoxy anthracycline antibiotics
US4309503A (en) * 1978-02-09 1982-01-05 Farmitalia Carlo Erba S.P.A. Preparation of 11-deoxy anthracycline antibiotics
NL7900869A (nl) * 1978-02-09 1979-08-13 Erba Farmitalia Anthracyclinenantibiotica.
US4345070A (en) * 1980-09-29 1982-08-17 Farmitalia Carlo Erba S.P.A. Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin
US4353894A (en) * 1980-10-27 1982-10-12 Sri International 5-Iminodoxorubicin
US5138042A (en) * 1981-05-28 1992-08-11 Farmitalia Carlo Erba S.P.A. 6-deoxyanthracyclines
GB8317037D0 (en) * 1983-06-23 1983-07-27 Erba Farmitalia 6-deoxyanthracyclines
IT1210476B (it) * 1981-05-28 1989-09-14 Erba Farmitalia Antracicline.
JPS5842878B2 (ja) * 1981-12-02 1983-09-22 名糖産業株式会社 １２−オキソコラン酸トシルヒドラゾン化合物、その製法ならびに利用
US4515720A (en) * 1983-03-11 1985-05-07 Oregon Graduate Center For Study & Research Method of synthesizing a late-stage intermediate to 11-deoxydaunorubicin and 11-deoxyadriamycin, and two precursors to the object intermediate
DE3446052A1 (de) * 1984-12-18 1986-07-17 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4710564A (en) * 1985-01-18 1987-12-01 Microbial Chemistry Research Foundation Anthracycline compounds
JPS6216495A (ja) * 1985-03-01 1987-01-24 Microbial Chem Res Found アンスラサイクリン化合物の３′デアミノ−３′−（４−モルホリニル）誘導体およびその用途
JPS61167696A (ja) * 1985-01-18 1986-07-29 Kirin Brewery Co Ltd アンスラサイクリン化合物およびその用途
JPS6293298A (ja) * 1985-10-17 1987-04-28 Kirin Brewery Co Ltd アンスラサイクリン化合物およびその用途
GB8617742D0 (en) * 1986-07-21 1986-08-28 Erba Farmitalia 6-amino anthracyclines
GB2196626B (en) * 1986-10-15 1990-09-19 Erba Farmitalia Antitumor anthracycline glycosides, their preparation, intermediates thereof, and compositions and use therefor
DE3641833A1 (de) * 1986-12-08 1988-06-09 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
NZ224252A (en) * 1987-04-21 1991-09-25 Erba Carlo Spa An anthracycline glycoside and its preparation
GB8803076D0 (en) * 1988-02-10 1988-03-09 Erba Carlo Spa 3'-deamino-4'-deoxy-4'-amino anthracyclines
US5412081A (en) * 1989-02-07 1995-05-02 Farmitalia Carlo Erba S.R.L. New 4'-epi-4'-amino anthracyclines
GB2238540B (en) * 1989-11-29 1993-09-29 Erba Carlo Spa 13-deoxy-4'-deoxy-4'-iodoanthracyclines
ES2155452T3 (es) * 1992-09-08 2001-05-16 Univ Vermont Isoquinoindazol-6-(2h)-onas sustituidas con 2-aminoalquil-5-aminoalquilamino con actividad antitumoral.
US6153193A (en) * 1993-04-28 2000-11-28 Supratek Pharma Inc. Compositions for targeting biological agents
US5817321A (en) * 1992-10-08 1998-10-06 Supratek Pharma, Inc. Biological agent compositions
GB9325417D0 (en) * 1993-12-13 1994-02-16 Erba Carlo Spa 3'- aziridino-anthracycline derivatives
JPH08259588A (ja) * 1995-03-20 1996-10-08 Mercian Corp 新規アントラサイクリン抗生物質

Also Published As

Publication number Publication date
EP1600161A2 (en) 2005-11-30
CZ302124B6 (cs) 2010-11-03
HUP0002717A3 (en) 2001-12-28
CZ2000471A3 (cs) 2000-11-15
US5948896A (en) 1999-09-07
CN1270522A (zh) 2000-10-18
IL134494A0 (en) 2001-04-30
BR9811147A (pt) 2000-07-25
BR9811147B1 (pt) 2011-09-06
WO1999008687A1 (en) 1999-02-25
KR20010022848A (ko) 2001-03-26
HU0002717D0 (en) 2000-08-28
CA2297149A1 (en) 1999-02-25
EP1011687A1 (en) 2000-06-28
EP1011687A4 (en) 2003-08-27
AU739033B2 (en) 2001-10-04
NZ502247A (en) 2001-08-31
IL134494A (en) 2007-07-24
EP1600161A3 (en) 2008-04-02
JP2001515040A (ja) 2001-09-18
JP4603684B2 (ja) 2010-12-22
AU8780698A (en) 1999-03-08
HUP0002717A2 (hu) 2000-12-28
JP2010215662A (ja) 2010-09-30
KR100516105B1 (ko) 2005-09-21
RU2233165C2 (ru) 2004-07-27
CA2297149C (en) 2007-03-27
CN1154499C (zh) 2004-06-23

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