ID18613A - Oksadiazol baru, proses pembuatannya serta penggunaannya sebagai komposisi farmasi - Google Patents

Oksadiazol baru, proses pembuatannya serta penggunaannya sebagai komposisi farmasi

Info

Publication number
ID18613A
ID18613A IDP973449A ID973449A ID18613A ID 18613 A ID18613 A ID 18613A ID P973449 A IDP973449 A ID P973449A ID 973449 A ID973449 A ID 973449A ID 18613 A ID18613 A ID 18613A
Authority
ID
Indonesia
Prior art keywords
oxadiazol
making
new
pharmaceutical composition
pharmaceutical
Prior art date
Application number
IDP973449A
Other languages
English (en)
Indonesian (id)
Inventor
Michael Brenner
Roland Maier
Marion Wienrich
Thomas Weiser
Rainer Palluk
Wolf-Dietrich Bechtel
Angelo Sagrada
Helmut Ensinger
Uwe Pschorn
Raffaele Cesana
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of ID18613A publication Critical patent/ID18613A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IDP973449A 1996-10-18 1997-10-16 Oksadiazol baru, proses pembuatannya serta penggunaannya sebagai komposisi farmasi ID18613A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19643037A DE19643037A1 (de) 1996-10-18 1996-10-18 Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ID18613A true ID18613A (id) 1998-04-23

Family

ID=7809114

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP973449A ID18613A (id) 1996-10-18 1997-10-16 Oksadiazol baru, proses pembuatannya serta penggunaannya sebagai komposisi farmasi

Country Status (32)

Country Link
US (1) US6277872B1 (bg)
EP (1) EP0934288B1 (bg)
JP (1) JP3333523B2 (bg)
KR (1) KR20000049253A (bg)
CN (1) CN1086698C (bg)
AR (1) AR008496A1 (bg)
AT (1) ATE315034T1 (bg)
AU (1) AU737552B2 (bg)
BG (1) BG103251A (bg)
BR (1) BR9714354A (bg)
CA (1) CA2268954C (bg)
CO (1) CO4920253A1 (bg)
CZ (1) CZ138099A3 (bg)
DE (2) DE19643037A1 (bg)
EE (1) EE9900147A (bg)
ES (1) ES2256880T3 (bg)
HK (1) HK1020956A1 (bg)
HR (1) HRP970553A2 (bg)
HU (1) HUP0001652A3 (bg)
ID (1) ID18613A (bg)
IL (1) IL129315A0 (bg)
NO (1) NO312512B1 (bg)
NZ (1) NZ335598A (bg)
PE (1) PE11199A1 (bg)
PL (1) PL332432A1 (bg)
RU (1) RU2182905C2 (bg)
SK (1) SK49999A3 (bg)
TR (1) TR199900848T2 (bg)
TW (1) TW413678B (bg)
WO (1) WO1998017652A1 (bg)
YU (1) YU40997A (bg)
ZA (1) ZA979220B (bg)

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IT1300056B1 (it) * 1998-04-17 2000-04-05 Boehringer Ingelheim Italia Eterocicli con anello a 6 termini difenil-sostituiti loro procedimento di preparazione e loro impiego come farmaci
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
DE60027546T2 (de) 1999-02-15 2007-04-26 Eisai Co., Ltd. Heterodiazinon-derivate
DK1070708T3 (da) 1999-07-21 2004-05-10 Hoffmann La Roche Triazolderivater
US6660753B2 (en) 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
MXPA02001764A (es) * 1999-08-19 2004-03-19 Nps Pharma Inc Compuestos heteropoliciclicos y su uso como antagonistas de receptor de glutamato metabotropico.
EP1582519A3 (en) * 1999-08-19 2005-12-21 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
US6579880B2 (en) * 2000-06-06 2003-06-17 Ortho-Mcneil Pharmaceutical, Inc. Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8
EP1300396B1 (en) 2000-06-12 2009-01-14 Eisai R&D Management Co., Ltd. 1,2-dihydropyridine compounds, process for preparation of the same and use thereof
KR100770327B1 (ko) * 2000-09-18 2007-10-25 에자이 알앤드디 매니지먼트 가부시키가이샤 피리다지논 및 트리아지논 화합물류 및 그들의 의약 용도
RU2319701C2 (ru) * 2001-02-21 2008-03-20 Астразенека Аб ГЕТЕРОПОЛИЦИКЛИЧЕСКОЕ СОЕДИНЕНИЕ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ АНТАГОНИСТИЧЕСКОЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ МЕТАБОТРОПНЫХ ГЛЮТАМАТНЫХ РЕЦЕПТОРОВ mGluR ГРУППЫ I
AU2002341921B2 (en) * 2001-10-04 2007-05-31 Merck Sharp & Dohme Corp. Heteroaryl substituted tetrazole modulators of metabotropic glutamate receptor-5
MY151199A (en) 2001-11-02 2014-04-30 Rigel Pharmaceuticals Inc Substituted diphenyl heterocycles useful for treating hcv infection
GB0129260D0 (en) 2001-12-06 2002-01-23 Eisai London Res Lab Ltd Pharmaceutical compositions and their uses
NZ537980A (en) 2002-08-23 2007-08-31 Rigel Pharmaceuticals Inc Pyridyl substituted heterocycles useful for treating or preventing HCV infection
GB0303503D0 (en) * 2003-02-14 2003-03-19 Novartis Ag Organic compounds
EP1620412A2 (en) 2003-05-02 2006-02-01 Rigel Pharmaceuticals, Inc. Heterocyclic compounds and hydro isomers thereof
US7115642B2 (en) 2003-05-02 2006-10-03 Rigel Pharmaceuticals, Inc. Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating HCV infection
US7220745B2 (en) 2003-05-15 2007-05-22 Rigel Pharmaceuticals Heterocyclic compounds useful to treat HCV
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
JP4958560B2 (ja) * 2003-12-24 2012-06-20 プロシディオン・リミテッド Ｇｐｃｒ受容体作動薬としてのヘテロ環誘導体
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
CA2603959A1 (en) * 2005-04-08 2006-10-19 Eisai R & D Management Co., Ltd. Therapeutic agent for dyskinesia
WO2007027230A2 (en) 2005-05-02 2007-03-08 Rigel Pharmaceuticals, Inc. Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses
GB0510142D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds A1
HUP0500920A2 (en) * 2005-10-05 2007-07-30 Richter Gedeon Nyrt Oxadiazole derivatives, process for their preparation and their use
NZ577111A (en) * 2006-12-15 2012-05-25 Abbott Lab Novel oxadiazole compounds
US20110207704A1 (en) * 2006-12-15 2011-08-25 Abbott Laboratories Novel Oxadiazole Compounds
JO2701B1 (en) 2006-12-21 2013-03-03 جلاكسو جروب ليميتد Vehicles
KR20100083814A (ko) * 2007-10-04 2010-07-22 메르크 세로노 에스. 에이. 옥사디아졸 디아릴 화합물
US9045442B2 (en) * 2007-12-21 2015-06-02 University Of Notre Dame Du Lac Antibacterial compounds and methods of using same
DK2684873T3 (en) 2008-06-09 2019-04-01 Univ Muenchen Ludwig Maximilians PHARMACEUTICALS FOR INHIBITING AGGREGATION OF PROTEINS INVOLVED IN DISEASES CONNECTED WITH PROTEIN AGGREGATION AND / OR NEURODEGENERATIVE DISEASE
WO2011047129A1 (en) * 2009-10-15 2011-04-21 Southern Research Institute Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such
BR112015003824B1 (pt) * 2012-08-24 2022-10-04 Treventis Corporation Composto, composição farmacêutica e uso do composto
ES2734432T3 (es) 2014-02-27 2019-12-05 Treventis Corp Compuestos antiamiloides que contienen benzofurazano
EP3135114B1 (en) 2014-04-24 2019-03-20 Sumitomo Chemical Company, Limited Diaryl-azole compound
CA2962431A1 (en) * 2014-09-25 2016-03-31 University Of Notre Dame Du Lac Non-beta lactam antibiotics
CN107286174B (zh) * 2016-04-11 2020-08-18 上海勋和医药科技有限公司 取代2,4-(1h,3h)嘧啶二酮作为parp抑制剂及其应用
WO2018049404A1 (en) 2016-09-12 2018-03-15 University Of Notre Dame Du Lac Compounds for the treatment of clostridium difficile infection
JP7283699B2 (ja) 2017-05-12 2023-05-30 マックス－プランク－ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ 黒色腫の治療または予防において使用するためのフェニル－ヘテロ環－フェニル誘導体
US10676467B2 (en) 2017-06-30 2020-06-09 Washington University Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof
CN113226286A (zh) 2018-12-14 2021-08-06 卫材R&D管理有限公司 1,2-二氢吡啶化合物的水基药物制剂
EP4403184A1 (en) 2021-09-15 2024-07-24 University of The Ryukyus Pharmaceutical composition for use in treating cognitive decline, excess weight, or obesity
EP4403185A1 (en) 2021-09-15 2024-07-24 University of The Ryukyus Pharmaceutical composition for treating cognitive decline or for treating overweightness or obesity
EP4173485A1 (en) 2021-10-27 2023-05-03 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Protein aggregation inhibiting compounds for plant disease control

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US4003909A (en) * 1974-07-22 1977-01-18 E. R. Squibb & Sons, Inc. [(1,2,4-Oxadiazol-3-yl)phenyl]carbamic or thiocarbamic acid esters
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Also Published As

Publication number Publication date
SK49999A3 (en) 1999-11-08
CZ138099A3 (cs) 1999-11-17
BR9714354A (pt) 2000-04-11
PL332432A1 (en) 1999-09-13
US6277872B1 (en) 2001-08-21
JP3333523B2 (ja) 2002-10-15
EP0934288B1 (de) 2006-01-04
AU4867697A (en) 1998-05-15
HK1020956A1 (en) 2000-05-26
NO312512B1 (no) 2002-05-21
CN1233245A (zh) 1999-10-27
NO991815L (no) 1999-04-16
DE19643037A1 (de) 1998-04-23
DE59712543D1 (de) 2006-03-30
IL129315A0 (en) 2000-02-17
KR20000049253A (ko) 2000-07-25
ZA979220B (en) 1998-04-20
CA2268954C (en) 2006-06-13
ATE315034T1 (de) 2006-02-15
BG103251A (bg) 2000-02-29
CN1086698C (zh) 2002-06-26
HUP0001652A2 (hu) 2001-01-29
HUP0001652A3 (en) 2002-12-28
YU40997A (sh) 2000-10-30
EE9900147A (et) 1999-12-15
CA2268954A1 (en) 1998-04-30
TW413678B (en) 2000-12-01
NZ335598A (en) 2001-06-29
ES2256880T3 (es) 2006-07-16
AU737552B2 (en) 2001-08-23
PE11199A1 (es) 1999-03-03
HRP970553A2 (en) 1998-08-31
WO1998017652A1 (de) 1998-04-30
EP0934288A1 (de) 1999-08-11
AR008496A1 (es) 2000-01-19
JP2000505089A (ja) 2000-04-25
CO4920253A1 (es) 2000-05-29
TR199900848T2 (xx) 1999-06-21
NO991815D0 (no) 1999-04-16
RU2182905C2 (ru) 2002-05-27

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