HUT58309A - Process for producing new 6-/phenoxy/or phenyl-thio/-methyl/-4-hydroxy-tetrahydropyran-2-one derivatives and pharmaceutical compositions containing them as active components - Google Patents

Process for producing new 6-/phenoxy/or phenyl-thio/-methyl/-4-hydroxy-tetrahydropyran-2-one derivatives and pharmaceutical compositions containing them as active components

Info

Publication number
HUT58309A
HUT58309A HU892394A HU239489A HUT58309A HU T58309 A HUT58309 A HU T58309A HU 892394 A HU892394 A HU 892394A HU 239489 A HU239489 A HU 239489A HU T58309 A HUT58309 A HU T58309A
Authority
HU
Hungary
Prior art keywords
tetrahydropyran
thio
phenoxy
hydroxy
phenyl
Prior art date
Application number
HU892394A
Other languages
English (en)
Other versions
HU206312B (en
Inventor
Heiner Jendralla
Guenther Wess
Wilhelm Bartmann
Gerhard Beck
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3816388A external-priority patent/DE3816388A1/de
Priority claimed from DE19883819999 external-priority patent/DE3819999A1/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HUT58309A publication Critical patent/HUT58309A/hu
Publication of HU206312B publication Critical patent/HU206312B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/01Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton
    • C07C323/09Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
HU892394A 1988-05-13 1989-05-12 Process for producing new 6-/phenoxy/ or phenyl-thio/methyl/-4-hydroxy-tetrhyropiran-2-one derivatives and pharmaceutical compositions containing them as active components HU206312B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3816388A DE3816388A1 (de) 1988-05-13 1988-05-13 Neue-6-phenoxymethyl-4-hydroxytetrahydropyran-2-one und 6-thiophenoxymethyl-4-hydroxytetrahydropyran-2-one, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und neue phenole sowie thiophenole
DE19883819999 DE3819999A1 (de) 1988-06-11 1988-06-11 Neue 6-phenoxymethyl-4-hydroxytetrahydropyran-2-one und 6-thiphenoxymethyl-4-hydroxytetrahydropyran-2 -one, sowie die entsprechenden dihydroxycarbonsaeurederivate, salze und ester, verfahren zur herstellung dieser verbindung, ihre verwendung als arzneimittel, pharmazeutische praeparate und neue phenole sowie thiophenole

Publications (2)

Publication Number Publication Date
HUT58309A true HUT58309A (en) 1992-02-28
HU206312B HU206312B (en) 1992-10-28

Family

ID=25868078

Family Applications (1)

Application Number Title Priority Date Filing Date
HU892394A HU206312B (en) 1988-05-13 1989-05-12 Process for producing new 6-/phenoxy/ or phenyl-thio/methyl/-4-hydroxy-tetrhyropiran-2-one derivatives and pharmaceutical compositions containing them as active components

Country Status (16)

Country Link
EP (1) EP0341681B1 (hu)
JP (1) JP2833779B2 (hu)
KR (1) KR900018062A (hu)
AU (1) AU615060B2 (hu)
CA (1) CA1338018C (hu)
DE (1) DE58906520D1 (hu)
DK (1) DK235389A (hu)
ES (1) ES2061779T3 (hu)
FI (1) FI96684C (hu)
HU (1) HU206312B (hu)
IE (1) IE63298B1 (hu)
IL (1) IL90249A (hu)
NO (1) NO172538C (hu)
NZ (1) NZ229083A (hu)
PH (1) PH26257A (hu)
PT (1) PT90532B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929913A1 (de) * 1989-09-08 1991-04-04 Hoechst Ag 4-hydroxytetrahydropyran-2-one sowie die entsprechenden dihydroxycarbonsaeurederivate, salze und ester, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate sowie vorprodukte
KR950005791A (ko) * 1993-08-09 1995-03-20 후꾸야마 마사루 카르복실산 에스테르-유도체의 제조방법 및 그 방법에 사용되는 4- 플루오로비페닐 유도체
US9045684B2 (en) * 2012-07-30 2015-06-02 Jnc Corporation Liquid crystal composition, antioxidant and liquid crystal display device

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3530798A1 (de) * 1985-08-29 1987-03-05 Hoechst Ag 6-phenoxymethyl-4-hydroxytetrahydropyran-2-one, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
DE3674521D1 (de) * 1985-08-29 1990-10-31 Hoechst Ag 6-phenoxymethyl-4-hydroxytetrahydropyran-2-one, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte.
DE3632893A1 (de) * 1986-09-27 1988-04-07 Hoechst Ag 4-(r)-hydroxy-6(s)-arylthiomethyl-tetrahydropyran-2-one, deren entsprechende sulfoxide und sulfone, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
DE3929913A1 (de) * 1989-09-08 1991-04-04 Hoechst Ag 4-hydroxytetrahydropyran-2-one sowie die entsprechenden dihydroxycarbonsaeurederivate, salze und ester, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate sowie vorprodukte

Also Published As

Publication number Publication date
NO172538B (no) 1993-04-26
EP0341681B1 (de) 1993-12-29
PH26257A (en) 1992-04-01
NO891937D0 (no) 1989-05-12
KR900018062A (ko) 1990-12-20
FI892291A (fi) 1989-11-14
FI892291A0 (fi) 1989-05-11
JPH01319472A (ja) 1989-12-25
NZ229083A (en) 1990-12-21
NO891937L (no) 1989-11-14
PT90532B (pt) 1994-11-30
AU615060B2 (en) 1991-09-19
AU3471589A (en) 1989-12-21
DK235389A (da) 1989-11-14
FI96684C (fi) 1996-08-12
IE63298B1 (en) 1995-04-05
IL90249A (en) 1994-01-25
DE58906520D1 (de) 1994-02-10
IL90249A0 (en) 1989-12-15
EP0341681A2 (de) 1989-11-15
FI96684B (fi) 1996-04-30
CA1338018C (en) 1996-01-30
HU206312B (en) 1992-10-28
JP2833779B2 (ja) 1998-12-09
NO172538C (no) 1993-08-04
PT90532A (pt) 1989-11-30
ES2061779T3 (es) 1994-12-16
IE891554L (en) 1989-11-13
EP0341681A3 (en) 1990-05-16
DK235389D0 (da) 1989-05-12

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee