HUT57754A - Process for producing 5-braces open 2-brackets open n-(2-amino-2-oxoethyl)-n-methylamino brackets closed -ethyl braces closed-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-(5h)-benzothiazepin-4-one derivatives and for their pharmaceutical application - Google Patents

Process for producing 5-braces open 2-brackets open n-(2-amino-2-oxoethyl)-n-methylamino brackets closed -ethyl braces closed-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-(5h)-benzothiazepin-4-one derivatives and for their pharmaceutical application

Info

Publication number
HUT57754A
HUT57754A HU906466A HU646690A HUT57754A HU T57754 A HUT57754 A HU T57754A HU 906466 A HU906466 A HU 906466A HU 646690 A HU646690 A HU 646690A HU T57754 A HUT57754 A HU T57754A
Authority
HU
Hungary
Prior art keywords
braces
closed
brackets
open
benzothiazepin
Prior art date
Application number
HU906466A
Other languages
English (en)
Other versions
HU906466D0 (en
Inventor
Jean-Claude Muller
Gilbert Lassalle
Colombe Denys
Alistair Lochead
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of HU906466D0 publication Critical patent/HU906466D0/hu
Publication of HUT57754A publication Critical patent/HUT57754A/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU906466A 1989-10-17 1990-10-16 Process for producing 5-braces open 2-brackets open n-(2-amino-2-oxoethyl)-n-methylamino brackets closed -ethyl braces closed-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-(5h)-benzothiazepin-4-one derivatives and for their pharmaceutical application HUT57754A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8913540A FR2653122B1 (fr) 1989-10-17 1989-10-17 Derives de 5-[2-[[2-amino-2-oxoethyl]methylamino]ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5(5h)-benzothiazepine-4-one, leur preparation et leur application en therapeutique.

Publications (2)

Publication Number Publication Date
HU906466D0 HU906466D0 (en) 1991-04-29
HUT57754A true HUT57754A (en) 1991-12-30

Family

ID=9386468

Family Applications (1)

Application Number Title Priority Date Filing Date
HU906466A HUT57754A (en) 1989-10-17 1990-10-16 Process for producing 5-braces open 2-brackets open n-(2-amino-2-oxoethyl)-n-methylamino brackets closed -ethyl braces closed-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-(5h)-benzothiazepin-4-one derivatives and for their pharmaceutical application

Country Status (14)

Country Link
EP (1) EP0424214A1 (hu)
JP (1) JPH03133970A (hu)
KR (1) KR910007901A (hu)
AU (1) AU6479690A (hu)
CA (1) CA2027738A1 (hu)
FI (1) FI905089A0 (hu)
FR (1) FR2653122B1 (hu)
HU (1) HUT57754A (hu)
IE (1) IE903720A1 (hu)
IL (1) IL95931A0 (hu)
NO (1) NO904470L (hu)
NZ (1) NZ235717A (hu)
PT (1) PT95606A (hu)
ZA (1) ZA908267B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69411387T2 (de) * 1994-09-16 1999-02-25 Orion Corp. FERMION, Espoo Verfahren zur Herstellung von pharmazeutisch aktiven Benzothiazepinderivaten.
WO2005035505A2 (en) * 2003-09-30 2005-04-21 Artesian Therapeutics, Inc. Compounds with phosphodiesterase inhibiting and calcium channel blocking activities

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538492A (de) * 1970-10-07 1973-06-30 Hoffmann La Roche Verfahren zur Herstellung von Benzodiazepin-Derivaten
FR2624117B1 (fr) * 1987-12-08 1991-02-22 Synthelabo Derives de hydroxy-3 (methoxy-4 phenyl)-2 (methylamino-2 ethyl)-5 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique
FR2630109B1 (fr) * 1988-04-19 1991-11-29 Synthelabo Derives de ((n-(amino-2 oxo-2 ethyl)methylamino)-2 ethyl)-5 hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
IL95931A0 (en) 1991-07-18
NO904470L (no) 1991-04-18
NO904470D0 (no) 1990-10-16
FR2653122A1 (fr) 1991-04-19
JPH03133970A (ja) 1991-06-07
EP0424214A1 (fr) 1991-04-24
AU6479690A (en) 1991-07-11
CA2027738A1 (en) 1991-04-18
HU906466D0 (en) 1991-04-29
FR2653122B1 (fr) 1994-04-15
FI905089A0 (fi) 1990-10-16
ZA908267B (en) 1991-08-28
PT95606A (pt) 1991-09-13
IE903720A1 (en) 1991-04-24
NZ235717A (en) 1991-12-23
KR910007901A (ko) 1991-05-30

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Legal Events

Date Code Title Description
DFC9 Refusal of application