IL95931A0 - 5-(2-((2-amino-2-oxoethyl)(methyl)amino)ethyl)-2,3-dihydro-3-hydroxy-2-(4-methoxy-phenyl)-1,5(5h)-benzothiazepin-4-one derivatives,their preparation and their application in therapy - Google Patents

5-(2-((2-amino-2-oxoethyl)(methyl)amino)ethyl)-2,3-dihydro-3-hydroxy-2-(4-methoxy-phenyl)-1,5(5h)-benzothiazepin-4-one derivatives,their preparation and their application in therapy

Info

Publication number
IL95931A0
IL95931A0 IL95931A IL9593190A IL95931A0 IL 95931 A0 IL95931 A0 IL 95931A0 IL 95931 A IL95931 A IL 95931A IL 9593190 A IL9593190 A IL 9593190A IL 95931 A0 IL95931 A0 IL 95931A0
Authority
IL
Israel
Prior art keywords
amino
benzothiazepin
oxoethyl
dihydro
methoxy
Prior art date
Application number
IL95931A
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL95931A0 publication Critical patent/IL95931A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL95931A 1989-10-17 1990-10-16 5-(2-((2-amino-2-oxoethyl)(methyl)amino)ethyl)-2,3-dihydro-3-hydroxy-2-(4-methoxy-phenyl)-1,5(5h)-benzothiazepin-4-one derivatives,their preparation and their application in therapy IL95931A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8913540A FR2653122B1 (en) 1989-10-17 1989-10-17 DERIVATIVES OF 5- [2 - [[2-AMINO-2-OXOETHYL] METHYLAMINO] ETHYL] -2,3-DIHYDRO-3-HYDROXY-2- (4-METHOXYPHENYL) -1.5 (5H) -BENZOTHIAZEPINE-4 -ONE, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS.

Publications (1)

Publication Number Publication Date
IL95931A0 true IL95931A0 (en) 1991-07-18

Family

ID=9386468

Family Applications (1)

Application Number Title Priority Date Filing Date
IL95931A IL95931A0 (en) 1989-10-17 1990-10-16 5-(2-((2-amino-2-oxoethyl)(methyl)amino)ethyl)-2,3-dihydro-3-hydroxy-2-(4-methoxy-phenyl)-1,5(5h)-benzothiazepin-4-one derivatives,their preparation and their application in therapy

Country Status (14)

Country Link
EP (1) EP0424214A1 (en)
JP (1) JPH03133970A (en)
KR (1) KR910007901A (en)
AU (1) AU6479690A (en)
CA (1) CA2027738A1 (en)
FI (1) FI905089A0 (en)
FR (1) FR2653122B1 (en)
HU (1) HUT57754A (en)
IE (1) IE903720A1 (en)
IL (1) IL95931A0 (en)
NO (1) NO904470L (en)
NZ (1) NZ235717A (en)
PT (1) PT95606A (en)
ZA (1) ZA908267B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0702009B1 (en) * 1994-09-16 1998-07-01 Orion Corporation Fermion Method for the preparation of pharmaceutically active benzothiazepine derivatives
WO2005035505A2 (en) * 2003-09-30 2005-04-21 Artesian Therapeutics, Inc. Compounds with phosphodiesterase inhibiting and calcium channel blocking activities

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538492A (en) * 1970-10-07 1973-06-30 Hoffmann La Roche Process for the preparation of benzodiazepine derivatives
FR2624117B1 (en) * 1987-12-08 1991-02-22 Synthelabo HYDROXY-3 (METHOXY-4 PHENYL) -2 (METHYLAMINO-2 ETHYL) -5 DIHYDRO-2,3 5H-BENZOTHIAZEPINE-1,5 ONE-4 DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2630109B1 (en) * 1988-04-19 1991-11-29 Synthelabo DERIVATIVES OF ((N- (2-AMINO-2 OXO-2 ETHYL) METHYLAMINO) -2 ETHYL) -5 HYDROXY-3 (METHOXY-4 PHENYL) -2 DIHYDRO-2,3 5H-BENZOTHIAZEPINE-1,5 ONE-4, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS

Also Published As

Publication number Publication date
IE903720A1 (en) 1991-04-24
FI905089A0 (en) 1990-10-16
ZA908267B (en) 1991-08-28
JPH03133970A (en) 1991-06-07
FR2653122A1 (en) 1991-04-19
HU906466D0 (en) 1991-04-29
HUT57754A (en) 1991-12-30
KR910007901A (en) 1991-05-30
NO904470L (en) 1991-04-18
CA2027738A1 (en) 1991-04-18
EP0424214A1 (en) 1991-04-24
AU6479690A (en) 1991-07-11
NZ235717A (en) 1991-12-23
NO904470D0 (en) 1990-10-16
PT95606A (en) 1991-09-13
FR2653122B1 (en) 1994-04-15

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