HUT55394A - Process for producing pirrolidino-piperazine-dion derivatives and pharmaceutical compositions containing them as active components - Google Patents
Process for producing pirrolidino-piperazine-dion derivatives and pharmaceutical compositions containing them as active componentsInfo
- Publication number
- HUT55394A HUT55394A HU894542A HU454289A HUT55394A HU T55394 A HUT55394 A HU T55394A HU 894542 A HU894542 A HU 894542A HU 454289 A HU454289 A HU 454289A HU T55394 A HUT55394 A HU T55394A
- Authority
- HU
- Hungary
- Prior art keywords
- pirrolidino
- piperazine
- producing
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3830096A DE3830096A1 (de) | 1988-09-03 | 1988-09-03 | Piperazindione mit psychotroper wirkung |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT55394A true HUT55394A (en) | 1991-05-28 |
HU203891B HU203891B (en) | 1991-10-28 |
Family
ID=6362300
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU894542A HU203891B (en) | 1988-09-03 | 1989-09-01 | Process for producing pyrrolidino-piperazine-dion derivatives and pharmaceutical compositions contianing them as active components |
Country Status (13)
Country | Link |
---|---|
US (1) | US5091427A (hu) |
EP (1) | EP0362555A1 (hu) |
JP (1) | JPH02115175A (hu) |
KR (1) | KR900004710A (hu) |
AU (1) | AU627491B2 (hu) |
DE (1) | DE3830096A1 (hu) |
DK (1) | DK435289A (hu) |
FI (1) | FI894097A (hu) |
HU (1) | HU203891B (hu) |
IL (1) | IL91496A0 (hu) |
NO (1) | NO893524L (hu) |
PT (1) | PT91616A (hu) |
ZA (1) | ZA896717B (hu) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4027607A1 (de) * | 1990-08-31 | 1992-03-05 | Bayer Ag | Heterocyclische verbindungen |
US6143746A (en) * | 1994-01-21 | 2000-11-07 | Icos Corporation | Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use |
GB9514465D0 (en) * | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Chemical compounds |
GB9401090D0 (en) | 1994-01-21 | 1994-03-16 | Glaxo Lab Sa | Chemical compounds |
ES2095811B1 (es) * | 1995-07-28 | 1997-08-01 | Univ Madrid Complutense | Nuevos derivados de arilpiperazinas. |
WO1996006846A1 (es) * | 1994-09-01 | 1996-03-07 | Universidad Complutense De Madrid | Nuevos derivados de arilpiperazinas |
ES2082727B1 (es) * | 1994-09-01 | 1996-10-16 | Univ Madrid Complutense | Nuevos derivados de arilpiperazinas. |
GB9514473D0 (en) * | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Chemical compounds |
GB9514464D0 (en) | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Medicaments |
EE9800390A (et) | 1996-05-10 | 1999-06-15 | Icos Corporation | Karboliini derivaadid |
GB0414093D0 (en) | 2004-06-23 | 2004-07-28 | Glaxo Group Ltd | Novel compounds |
JP2013509391A (ja) | 2009-10-30 | 2013-03-14 | グラクソ グループ リミテッド | (3r,6r)−3−(2,3−ジヒドロ−1h−インデン−2−イル)−1−[(1r)−1−(2,6−ジメチル−3−ピリジニル)−2−(4−モルホリニル)−2−オキソエチル]−6−[(1s)−1−メチルプロピル]−2,5−ピペラジンジオンの新規結晶性形態 |
JP2012246224A (ja) * | 2011-05-25 | 2012-12-13 | Suntory Holdings Ltd | 抗認知症および学習記憶改善剤 |
JP6291158B2 (ja) * | 2012-11-21 | 2018-03-14 | サントリーホールディングス株式会社 | 抗認知症および学習記憶改善剤 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3194731A (en) * | 1963-03-11 | 1965-07-13 | American Cyanamid Co | Method for hypnosis and tranquilization with piperazinedione derivatives |
US3384639A (en) * | 1964-05-28 | 1968-05-21 | Asahi Chemical Ind | Method for producing 3, 6-dioxo-2, 5-dimethylpiperazine |
CH560201A5 (en) * | 1969-03-11 | 1975-03-27 | Hoffmann La Roche | 1 4-benzodiazepin derivs anti-convulsive, - muscle relaxant, tranquillising |
US3644384A (en) * | 1969-06-09 | 1972-02-22 | Sterling Drug Inc | Certain 2-(alpha-haloacetyl) - 1 2 3 4-tetrahydro - 9h - pyrido(3 4-b)indole-3-carboxylates and derivatives |
DE2114230C2 (de) * | 1971-03-24 | 1987-03-19 | Vsesojuznyj naučno-issledovatel'skij institut imeni Sergo Ordžonikidze, Moskau/Moskva | Verfahren zur Herstellung von 8-Methyl-2,3,3a,4,5,6-hexahydro-1H-pyrazino(3,2,1-j,k)carbazolhydrochlorid |
AR206504A1 (es) * | 1972-11-03 | 1976-07-30 | Lepetit Spa | Un procedimiento para preparar 6,7,8,8a-tetrahidro-pirrol(1,2-a)pirazina-1(2h),4(3h)-dionas |
WO1980000216A1 (en) * | 1978-07-10 | 1980-02-21 | Univ Illinois | Inhibition by peptides of tolerance to and dependence on morphine |
EP0008186A1 (en) * | 1978-08-08 | 1980-02-20 | Beecham Group Plc | Cyclic diamides, a process for their preparation and their pharmaceutical compositions |
US4289759A (en) * | 1980-06-23 | 1981-09-15 | Ortho Pharmaceutical Corporation | Immunoregulatory diketopiperazine compounds |
GB8427735D0 (en) * | 1984-11-02 | 1984-12-12 | Fujisawa Pharmaceutical Co | Piperazine compound |
DK181687A (da) * | 1986-04-23 | 1987-10-24 | Fujisawa Pharmaceutical Co | Piperazinderivater og fremgangsmaade til fremstiling deraf |
-
1988
- 1988-09-03 DE DE3830096A patent/DE3830096A1/de not_active Withdrawn
-
1989
- 1989-08-31 FI FI894097A patent/FI894097A/fi not_active Application Discontinuation
- 1989-08-31 EP EP89116093A patent/EP0362555A1/de not_active Withdrawn
- 1989-09-01 KR KR1019890012618A patent/KR900004710A/ko not_active Application Discontinuation
- 1989-09-01 JP JP1224733A patent/JPH02115175A/ja active Pending
- 1989-09-01 PT PT91616A patent/PT91616A/pt unknown
- 1989-09-01 AU AU40957/89A patent/AU627491B2/en not_active Expired - Fee Related
- 1989-09-01 US US07/401,842 patent/US5091427A/en not_active Expired - Fee Related
- 1989-09-01 HU HU894542A patent/HU203891B/hu not_active IP Right Cessation
- 1989-09-01 DK DK435289A patent/DK435289A/da not_active Application Discontinuation
- 1989-09-01 NO NO89893524A patent/NO893524L/no unknown
- 1989-09-01 ZA ZA896717A patent/ZA896717B/xx unknown
- 1989-09-01 IL IL91496A patent/IL91496A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NO893524L (no) | 1990-03-05 |
EP0362555A1 (de) | 1990-04-11 |
JPH02115175A (ja) | 1990-04-27 |
NO893524D0 (no) | 1989-09-01 |
AU4095789A (en) | 1990-03-08 |
AU627491B2 (en) | 1992-08-27 |
KR900004710A (ko) | 1990-04-12 |
IL91496A0 (en) | 1990-04-29 |
FI894097A (fi) | 1990-03-04 |
DE3830096A1 (de) | 1990-03-15 |
PT91616A (pt) | 1990-03-30 |
US5091427A (en) | 1992-02-25 |
FI894097A0 (fi) | 1989-08-31 |
DK435289D0 (da) | 1989-09-01 |
HU203891B (en) | 1991-10-28 |
ZA896717B (en) | 1990-05-30 |
DK435289A (da) | 1990-03-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HMM4 | Cancellation of final prot. due to non-payment of fee |