HUT50789A - Process for producing renin inhibiting amino acid derivatives and pharmaceutical compositions comprising such compounds as active ingredient - Google Patents
Process for producing renin inhibiting amino acid derivatives and pharmaceutical compositions comprising such compounds as active ingredientInfo
- Publication number
- HUT50789A HUT50789A HU89763A HU76389A HUT50789A HU T50789 A HUT50789 A HU T50789A HU 89763 A HU89763 A HU 89763A HU 76389 A HU76389 A HU 76389A HU T50789 A HUT50789 A HU T50789A
- Authority
- HU
- Hungary
- Prior art keywords
- compounds
- amino acid
- active ingredient
- pharmaceutical compositions
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Furan Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3804793A DE3804793A1 (de) | 1988-02-16 | 1988-02-16 | Renin-hemmende aminosaeurederivate |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT50789A true HUT50789A (en) | 1990-03-28 |
HU203226B HU203226B (en) | 1991-06-28 |
Family
ID=6347510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU89763A HU203226B (en) | 1988-02-16 | 1989-02-15 | Process for producing renin-inhibiting amino acid derivatives and pharmaceutical compositions comprising such compounds as active ingredient |
Country Status (15)
Country | Link |
---|---|
US (1) | US5204357A (hu) |
EP (1) | EP0329013A3 (hu) |
JP (1) | JPH023665A (hu) |
KR (1) | KR890013053A (hu) |
CN (1) | CN1035286A (hu) |
AU (1) | AU626535B2 (hu) |
DE (1) | DE3804793A1 (hu) |
DK (1) | DK69389A (hu) |
FI (1) | FI890699A (hu) |
HU (1) | HU203226B (hu) |
IL (1) | IL89304A0 (hu) |
NO (1) | NO890635L (hu) |
NZ (1) | NZ227976A (hu) |
PT (1) | PT89730B (hu) |
ZA (1) | ZA891135B (hu) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3717631A1 (de) * | 1987-05-26 | 1988-12-15 | Merck Patent Gmbh | Aminosaeurederivate |
NZ235234A (en) * | 1989-09-12 | 1992-12-23 | Hoechst Ag | Renin-inhibiting amino acid derivatives and pharmaceutical compositions thereof |
CA2031735A1 (en) * | 1989-12-08 | 1991-06-09 | Daljit S. Dhanoa | Cyclic renin inhibitors containing 3(s)-amino-4-cyclohexyl-2(r)-hydroxy-butanoic acid or 4-cyclo-hexyl-(2r, 3s)-dihydroxybutanoic acid or related analogs |
US5330737A (en) * | 1991-12-06 | 1994-07-19 | Mallinckrodt Medical, Inc. | Nitrogen-sulfur ligands as opiate receptor drug mimics |
US6455734B1 (en) * | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
WO2014100730A1 (en) | 2012-12-21 | 2014-06-26 | Epizyme, Inc. | Prmt5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof |
JP2016505597A (ja) | 2012-12-21 | 2016-02-25 | エピザイム,インコーポレイティド | Prmt5阻害剤およびその使用 |
US9365555B2 (en) | 2012-12-21 | 2016-06-14 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
US9908887B2 (en) | 2012-12-21 | 2018-03-06 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
US8993555B2 (en) | 2012-12-21 | 2015-03-31 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
US10653693B2 (en) | 2014-08-04 | 2020-05-19 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4435329A (en) * | 1981-10-16 | 1984-03-06 | American Cyanamid Company | Substituted N-(ω-aroylpropionyl) derivatives of α-amino acids and esters thereof |
DE3467754D1 (de) * | 1983-10-03 | 1988-01-07 | Squibb & Sons Inc | Enkephalinase inhibitors |
FI870474A (fi) * | 1986-02-07 | 1987-08-08 | Ciba Geigy Ag | Med svavelhaltiga grupper substituerade 5-amino-4-hydroxivalerylderivat. |
DE3732971A1 (de) * | 1987-09-30 | 1989-04-20 | Hoechst Ag | Renin-hemmende dipeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung |
-
1988
- 1988-02-16 DE DE3804793A patent/DE3804793A1/de not_active Withdrawn
-
1989
- 1989-02-09 EP EP19890102215 patent/EP0329013A3/de not_active Withdrawn
- 1989-02-14 FI FI890699A patent/FI890699A/fi not_active Application Discontinuation
- 1989-02-14 US US07/310,183 patent/US5204357A/en not_active Expired - Fee Related
- 1989-02-14 ZA ZA891135A patent/ZA891135B/xx unknown
- 1989-02-14 NZ NZ227976A patent/NZ227976A/xx unknown
- 1989-02-15 CN CN89100812A patent/CN1035286A/zh active Pending
- 1989-02-15 DK DK069389A patent/DK69389A/da not_active Application Discontinuation
- 1989-02-15 AU AU29977/89A patent/AU626535B2/en not_active Ceased
- 1989-02-15 NO NO89890635A patent/NO890635L/no unknown
- 1989-02-15 JP JP1033895A patent/JPH023665A/ja active Pending
- 1989-02-15 KR KR1019890001707A patent/KR890013053A/ko not_active Application Discontinuation
- 1989-02-15 HU HU89763A patent/HU203226B/hu not_active IP Right Cessation
- 1989-02-15 IL IL89304A patent/IL89304A0/xx not_active IP Right Cessation
- 1989-02-16 PT PT89730A patent/PT89730B/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2997789A (en) | 1989-08-17 |
PT89730B (pt) | 1994-03-31 |
EP0329013A3 (de) | 1991-03-13 |
EP0329013A2 (de) | 1989-08-23 |
IL89304A0 (en) | 1989-09-10 |
NZ227976A (en) | 1991-12-23 |
AU626535B2 (en) | 1992-08-06 |
PT89730A (pt) | 1989-10-04 |
NO890635L (no) | 1989-08-17 |
FI890699A (fi) | 1989-08-17 |
CN1035286A (zh) | 1989-09-06 |
ZA891135B (en) | 1989-10-25 |
HU203226B (en) | 1991-06-28 |
DE3804793A1 (de) | 1989-08-24 |
DK69389D0 (da) | 1989-02-15 |
FI890699A0 (fi) | 1989-02-14 |
DK69389A (da) | 1989-08-17 |
US5204357A (en) | 1993-04-20 |
JPH023665A (ja) | 1990-01-09 |
KR890013053A (ko) | 1989-09-21 |
NO890635D0 (no) | 1989-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HMM4 | Cancellation of final prot. due to non-payment of fee | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |