HUT48593A - Process for producing asymmetric 1,4-dihydropyridinecarboxylic acid esters - Google Patents
Process for producing asymmetric 1,4-dihydropyridinecarboxylic acid estersInfo
- Publication number
- HUT48593A HUT48593A HU886198A HU619888A HUT48593A HU T48593 A HUT48593 A HU T48593A HU 886198 A HU886198 A HU 886198A HU 619888 A HU619888 A HU 619888A HU T48593 A HUT48593 A HU T48593A
- Authority
- HU
- Hungary
- Prior art keywords
- acid esters
- producing asymmetric
- dihydropyridinecarboxylic acid
- reaction
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19873741540 DE3741540A1 (de) | 1987-12-08 | 1987-12-08 | Verfahren zur herstellung von unsymmetrischen dihydropyridinen |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT48593A true HUT48593A (en) | 1989-06-28 |
HU205074B HU205074B (en) | 1992-03-30 |
Family
ID=6342114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU886198A HU205074B (en) | 1987-12-08 | 1988-12-07 | Process for producing 4-(3-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid methyl ethyl ester |
Country Status (9)
Country | Link |
---|---|
US (1) | US4904789A (hu) |
EP (1) | EP0319814B1 (hu) |
JP (1) | JP2641542B2 (hu) |
AT (1) | ATE80619T1 (hu) |
CA (1) | CA1314289C (hu) |
DE (2) | DE3741540A1 (hu) |
ES (1) | ES2045070T3 (hu) |
GR (1) | GR3005718T3 (hu) |
HU (1) | HU205074B (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5310917A (en) * | 1991-09-13 | 1994-05-10 | Merck & Co., Inc. | Process for the preparation of 4-substituted-1,4-dihydropydrines |
IT1275939B1 (it) | 1995-03-20 | 1997-10-24 | Lusochimica Spa | Procedimento per la preparazione di 4 (nitrofenil) diidropiridine |
IT1283793B1 (it) * | 1996-08-23 | 1998-04-30 | Lusochimica Spa | Processo per la preparazione di diidropiridine |
US6265127B1 (en) * | 1999-12-15 | 2001-07-24 | Eastman Kodak Company | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers |
CN109232390A (zh) * | 2018-11-09 | 2019-01-18 | 黄石燕舞药业有限公司 | 一种基于三步法制备尼群地平的合成工艺 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
DE2117573C3 (de) * | 1971-04-10 | 1978-07-27 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von unsymmetrischen l,4-Dihydropyridin-3,5dicarbonsäureestern, sowie ihre Verwendung als Arzneimittel |
IL68604A0 (en) * | 1982-05-21 | 1983-09-30 | Haessle Ab | Processes for preparing therapeutically active dihydropyridines and intermediates for the processes |
DE3312283A1 (de) * | 1983-04-05 | 1984-10-18 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern |
-
1987
- 1987-12-08 DE DE19873741540 patent/DE3741540A1/de not_active Withdrawn
-
1988
- 1988-11-23 US US07/275,301 patent/US4904789A/en not_active Expired - Lifetime
- 1988-11-28 DE DE8888119772T patent/DE3874697D1/de not_active Expired - Lifetime
- 1988-11-28 EP EP88119772A patent/EP0319814B1/de not_active Expired - Lifetime
- 1988-11-28 ES ES88119772T patent/ES2045070T3/es not_active Expired - Lifetime
- 1988-11-28 AT AT88119772T patent/ATE80619T1/de not_active IP Right Cessation
- 1988-12-06 CA CA000585040A patent/CA1314289C/en not_active Expired - Lifetime
- 1988-12-07 HU HU886198A patent/HU205074B/hu not_active IP Right Cessation
- 1988-12-08 JP JP63308993A patent/JP2641542B2/ja not_active Expired - Lifetime
-
1992
- 1992-09-17 GR GR920401982T patent/GR3005718T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE3741540A1 (de) | 1989-06-22 |
US4904789A (en) | 1990-02-27 |
HU205074B (en) | 1992-03-30 |
JP2641542B2 (ja) | 1997-08-13 |
EP0319814B1 (de) | 1992-09-16 |
EP0319814A2 (de) | 1989-06-14 |
EP0319814A3 (en) | 1989-11-29 |
ATE80619T1 (de) | 1992-10-15 |
ES2045070T3 (es) | 1994-01-16 |
JPH01197470A (ja) | 1989-08-09 |
DE3874697D1 (de) | 1992-10-22 |
GR3005718T3 (hu) | 1993-06-07 |
CA1314289C (en) | 1993-03-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of definitive patent protection due to non-payment of fees |