IT1275939B1 - Procedimento per la preparazione di 4 (nitrofenil) diidropiridine - Google Patents
Procedimento per la preparazione di 4 (nitrofenil) diidropiridineInfo
- Publication number
- IT1275939B1 IT1275939B1 IT95MI000540A ITMI950540A IT1275939B1 IT 1275939 B1 IT1275939 B1 IT 1275939B1 IT 95MI000540 A IT95MI000540 A IT 95MI000540A IT MI950540 A ITMI950540 A IT MI950540A IT 1275939 B1 IT1275939 B1 IT 1275939B1
- Authority
- IT
- Italy
- Prior art keywords
- pct
- preparation
- diidropiridine
- nitrofenil
- procedure
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- HUMNYLRZRPPJDN-UHFFFAOYSA-N benzaldehyde Chemical compound O=CC1=CC=CC=C1 HUMNYLRZRPPJDN-UHFFFAOYSA-N 0.000 abstract 2
- BIWBFFZTZOHCRG-UHFFFAOYSA-N 4-(2-nitrophenyl)-1,2-dihydropyridine Chemical class [O-][N+](=O)C1=CC=CC=C1C1=CCNC=C1 BIWBFFZTZOHCRG-UHFFFAOYSA-N 0.000 abstract 1
- ZEYHEAKUIGZSGI-UHFFFAOYSA-M 4-methoxybenzoate Chemical compound COC1=CC=C(C([O-])=O)C=C1 ZEYHEAKUIGZSGI-UHFFFAOYSA-M 0.000 abstract 1
- WDJHALXBUFZDSR-UHFFFAOYSA-M acetoacetate Chemical compound CC(=O)CC([O-])=O WDJHALXBUFZDSR-UHFFFAOYSA-M 0.000 abstract 1
- CLGPABLPZDWCHL-UHFFFAOYSA-N benzoic acid;n-methylmethanamine Chemical compound CNC.OC(=O)C1=CC=CC=C1 CLGPABLPZDWCHL-UHFFFAOYSA-N 0.000 abstract 1
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000002081 enamines Chemical class 0.000 abstract 1
- QNGNSVIICDLXHT-UHFFFAOYSA-N para-ethylbenzaldehyde Natural products CCC1=CC=C(C=O)C=C1 QNGNSVIICDLXHT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI000540A IT1275939B1 (it) | 1995-03-20 | 1995-03-20 | Procedimento per la preparazione di 4 (nitrofenil) diidropiridine |
| AU51086/96A AU703214B2 (en) | 1995-03-20 | 1996-03-14 | Dimethylamine benzoate or p-anisate catalysed process for the preparation of (nitrophenyl)-dihydropyridines |
| AT96907468T ATE180471T1 (de) | 1995-03-20 | 1996-03-14 | Dimethylaminbenzoat ider p-anisat catalysiertes verfahren zur herstellung von 4-8nitrophenyl)- dihydropyridinen |
| DK96907468T DK0819117T3 (da) | 1995-03-20 | 1996-03-14 | Dimethylaminbenzoat- eller -p-anisatkatalyseret fremgangsmåde til fremstilling af 4-(nitrophenyl)dihydropyridiner |
| US08/894,389 US6015906A (en) | 1995-03-20 | 1996-03-14 | Dimethylamine benzoate or p-anisate catalysed process for the preparation of 4-(nitrophenyl)-dihydropyridines |
| PCT/EP1996/001090 WO1996029310A1 (en) | 1995-03-20 | 1996-03-14 | Dimethylamine benzoate or p-anisate catalysed process for the preparation of 4-(nitrophenyl)-dihydropyridines |
| ES96907468T ES2131394T3 (es) | 1995-03-20 | 1996-03-14 | Procedimiento para la preparacion de 4-(nitrofenil)dihidropiridinas catalizado con benzoato o p-anisato de dimetilamina. |
| DE69602596T DE69602596T2 (de) | 1995-03-20 | 1996-03-14 | Dimethylaminbenzoat ider p-anisat catalysiertes verfahren zur herstellung von 4-8nitrophenyl)-dihydropyridinen |
| CA002215837A CA2215837C (en) | 1995-03-20 | 1996-03-14 | Dimethylamine benzoate or p-anisate catalysed process for the preparation of 4-(nitrophenyl)-dihydropyridines |
| EP96907468A EP0819117B1 (en) | 1995-03-20 | 1996-03-14 | Dimethylamine benzoate or p-anisate catalysed process for the preparation of 4-(nitrophenyl)-dihydropyridines |
| JP52805396A JP3916252B2 (ja) | 1995-03-20 | 1996-03-14 | ジメチルアミン安息香酸塩若しくはアニス酸塩触媒による４−（ニトロフェニル）−ジヒドロピリジン類の製造プロセス |
| GR990402119T GR3031041T3 (en) | 1995-03-20 | 1999-08-19 | Dimethylamine benzoate or p-anisate catalysed process for the preparation of 4-(nitrophenyl)-dihydropyridines |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT95MI000540A IT1275939B1 (it) | 1995-03-20 | 1995-03-20 | Procedimento per la preparazione di 4 (nitrofenil) diidropiridine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI950540A0 ITMI950540A0 (it) | 1995-03-20 |
| ITMI950540A1 ITMI950540A1 (it) | 1996-09-20 |
| IT1275939B1 true IT1275939B1 (it) | 1997-10-24 |
Family
ID=11370961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT95MI000540A IT1275939B1 (it) | 1995-03-20 | 1995-03-20 | Procedimento per la preparazione di 4 (nitrofenil) diidropiridine |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6015906A (it) |
| EP (1) | EP0819117B1 (it) |
| JP (1) | JP3916252B2 (it) |
| AT (1) | ATE180471T1 (it) |
| AU (1) | AU703214B2 (it) |
| CA (1) | CA2215837C (it) |
| DE (1) | DE69602596T2 (it) |
| DK (1) | DK0819117T3 (it) |
| ES (1) | ES2131394T3 (it) |
| GR (1) | GR3031041T3 (it) |
| IT (1) | IT1275939B1 (it) |
| WO (1) | WO1996029310A1 (it) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8383134B2 (en) | 2007-03-01 | 2013-02-26 | Bioneedle Technologies Group B.V. | Biodegradable material based on opened starch |
| CN104860873A (zh) * | 2015-05-28 | 2015-08-26 | 石家庄学院 | 一种(s)-1,4-二氢吡啶钙离子拮抗剂的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3312283A1 (de) | 1983-04-05 | 1984-10-18 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von unsymmetrischen 1,4-dihydropyridincarbonsaeureestern |
| JPS6143165A (ja) | 1984-08-07 | 1986-03-01 | Otsuka Pharmaceut Co Ltd | ジヒドロピリジン誘導体の製造法 |
| DE3741540A1 (de) | 1987-12-08 | 1989-06-22 | Bayer Ag | Verfahren zur herstellung von unsymmetrischen dihydropyridinen |
| JPH04173761A (ja) * | 1990-11-06 | 1992-06-22 | Daicel Chem Ind Ltd | α―アルキルアクロレインの製造方法 |
-
1995
- 1995-03-20 IT IT95MI000540A patent/IT1275939B1/it active IP Right Grant
-
1996
- 1996-03-14 JP JP52805396A patent/JP3916252B2/ja not_active Expired - Lifetime
- 1996-03-14 US US08/894,389 patent/US6015906A/en not_active Expired - Lifetime
- 1996-03-14 WO PCT/EP1996/001090 patent/WO1996029310A1/en not_active Ceased
- 1996-03-14 EP EP96907468A patent/EP0819117B1/en not_active Expired - Lifetime
- 1996-03-14 AT AT96907468T patent/ATE180471T1/de active
- 1996-03-14 AU AU51086/96A patent/AU703214B2/en not_active Expired
- 1996-03-14 DE DE69602596T patent/DE69602596T2/de not_active Expired - Lifetime
- 1996-03-14 ES ES96907468T patent/ES2131394T3/es not_active Expired - Lifetime
- 1996-03-14 DK DK96907468T patent/DK0819117T3/da active
- 1996-03-14 CA CA002215837A patent/CA2215837C/en not_active Expired - Lifetime
-
1999
- 1999-08-19 GR GR990402119T patent/GR3031041T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2215837A1 (en) | 1996-09-26 |
| EP0819117B1 (en) | 1999-05-26 |
| JPH11505518A (ja) | 1999-05-21 |
| DE69602596T2 (de) | 1999-09-23 |
| AU5108696A (en) | 1996-10-08 |
| AU703214B2 (en) | 1999-03-18 |
| WO1996029310A1 (en) | 1996-09-26 |
| GR3031041T3 (en) | 1999-12-31 |
| JP3916252B2 (ja) | 2007-05-16 |
| ITMI950540A1 (it) | 1996-09-20 |
| ES2131394T3 (es) | 1999-07-16 |
| DK0819117T3 (da) | 1999-11-08 |
| EP0819117A1 (en) | 1998-01-21 |
| DE69602596D1 (de) | 1999-07-01 |
| ATE180471T1 (de) | 1999-06-15 |
| CA2215837C (en) | 2007-10-30 |
| ITMI950540A0 (it) | 1995-03-20 |
| US6015906A (en) | 2000-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |