HUT46046A - Process for producing compounds with nootropic effect and pharmaceutics comprising these as active ingredient - Google Patents

Process for producing compounds with nootropic effect and pharmaceutics comprising these as active ingredient

Info

Publication number
HUT46046A
HUT46046A HU871308A HU130887A HUT46046A HU T46046 A HUT46046 A HU T46046A HU 871308 A HU871308 A HU 871308A HU 130887 A HU130887 A HU 130887A HU T46046 A HUT46046 A HU T46046A
Authority
HU
Hungary
Prior art keywords
pharmaceutics
active ingredient
producing compounds
nootropic effect
nootropic
Prior art date
Application number
HU871308A
Other languages
English (en)
Other versions
HU203117B (en
Inventor
Franz Hock
Josef Scholtholt
Hansjoerg Urbach
Rainer Henning
Ulrich Lerch
Wolf-Ulrich Nickel
Wolfgang Rueger
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of HUT46046A publication Critical patent/HUT46046A/hu
Publication of HU203117B publication Critical patent/HU203117B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
HU871308A 1986-03-27 1987-03-25 Process for producing dipeptides and pharmaceutical compositions comprising such compounds as active ingredient HU203117B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863610391 DE3610391A1 (de) 1986-03-27 1986-03-27 Verbindungen mit nootroper wirkung, diese enthaltende mittel und deren verwendung bei der behandlung und prophylaxe cognitiver dysfunktionen

Publications (2)

Publication Number Publication Date
HUT46046A true HUT46046A (en) 1988-09-28
HU203117B HU203117B (en) 1991-05-28

Family

ID=6297417

Family Applications (2)

Application Number Title Priority Date Filing Date
HU896609A HU202118B (en) 1986-03-27 1987-03-25 Process for producing medical compositions comprising dipeptides with noothropic effect
HU871308A HU203117B (en) 1986-03-27 1987-03-25 Process for producing dipeptides and pharmaceutical compositions comprising such compounds as active ingredient

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU896609A HU202118B (en) 1986-03-27 1987-03-25 Process for producing medical compositions comprising dipeptides with noothropic effect

Country Status (25)

Country Link
EP (1) EP0243645B1 (hu)
JP (1) JPS62240698A (hu)
KR (1) KR870008841A (hu)
CN (1) CN1031267C (hu)
AT (1) ATE102954T1 (hu)
AU (1) AU621278B2 (hu)
CA (1) CA1341064C (hu)
CS (2) CS212687A3 (hu)
DD (1) DD280765A5 (hu)
DE (2) DE3610391A1 (hu)
DK (1) DK172221B1 (hu)
EG (1) EG18175A (hu)
ES (1) ES2061447T3 (hu)
FI (1) FI91876C (hu)
HU (2) HU202118B (hu)
IE (1) IE62456B1 (hu)
MA (1) MA20919A1 (hu)
NO (1) NO178546C (hu)
NZ (1) NZ219764A (hu)
OA (1) OA08506A (hu)
PH (1) PH27210A (hu)
PT (1) PT84564B (hu)
RU (1) RU1836335C (hu)
TN (1) TNSN87045A1 (hu)
ZA (1) ZA872230B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
US4743450A (en) * 1987-02-24 1988-05-10 Warner-Lambert Company Stabilized compositions
AU612137B2 (en) * 1987-04-27 1991-07-04 E.R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing an ace inhibitor
DE3731085A1 (de) * 1987-09-16 1989-04-06 Hoechst Ag Neue aminosaeureester, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE3739690A1 (de) * 1987-11-24 1989-06-08 Hoechst Ag Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen
DE3801587A1 (de) * 1988-01-21 1989-08-03 Hoechst Ag Neue aminosaeureglyceride, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
EP0331609A3 (de) * 1988-01-27 1992-07-01 Hoechst Aktiengesellschaft Angiotensin-Converting-Enzym-Hemmstoffe mit psychotroper Wirkung
DE3803225A1 (de) * 1988-02-04 1989-08-17 Hoechst Ag Aminosaeureamide mit psychotroper wirkung, verfahren zu ihrer herstellung, sie enthaltende mittel und deren verwendung
JPH01275529A (ja) * 1988-03-21 1989-11-06 E R Squibb & Sons Inc 晩発性運動障害の抑制治療剤
US5037821A (en) * 1988-06-01 1991-08-06 E. R. Squibb & Sons, Inc. Method for inhibiting loss of cognitive functions employing a calcium channel blocker alone or in combination with an ACE inhibitor
US5093129A (en) * 1989-01-30 1992-03-03 E. R. Squibb & Sons, Inc. Method for treating addiction to a drug of abuse employing an ace inhibitor
US5032578A (en) * 1990-09-17 1991-07-16 E. R. Squibb & Sons, Inc. Method for preventing or treating depression employing a combination of an ace inhibitor and a drug that acts at serotonin receptors
EP1372620A2 (en) * 2001-03-15 2004-01-02 Saegis Pharmaceuticals Methods for restoring cognitive function following systemic stress

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3174844D1 (en) * 1980-10-23 1986-07-24 Schering Corp Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
DE3300774A1 (de) * 1983-01-12 1984-07-12 Hoechst Ag, 6230 Frankfurt Neue spirocyclische aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue spirocyclische aminosaeuren als zwischenprodukte und verfahren zu deren herstellung

Also Published As

Publication number Publication date
MA20919A1 (fr) 1987-10-01
NO871282D0 (no) 1987-03-26
CN87102304A (zh) 1987-12-30
CS276179B6 (en) 1992-04-15
OA08506A (fr) 1988-07-29
IE62456B1 (en) 1995-02-08
CS276385B6 (en) 1992-05-13
RU1836335C (ru) 1993-08-23
FI91876B (fi) 1994-05-13
ZA872230B (en) 1987-09-21
HU203117B (en) 1991-05-28
ES2061447T3 (es) 1994-12-16
TNSN87045A1 (fr) 1990-01-01
DK153587A (da) 1987-09-28
CN1031267C (zh) 1996-03-13
EP0243645A3 (en) 1990-01-24
DE3789330D1 (de) 1994-04-21
ATE102954T1 (de) 1994-04-15
DK153587D0 (da) 1987-03-26
PH27210A (en) 1993-05-04
FI871304A (fi) 1987-09-28
NO178546B (no) 1996-01-08
CS651989A3 (en) 1992-05-13
JPS62240698A (ja) 1987-10-21
PT84564A (de) 1987-04-01
EP0243645A2 (de) 1987-11-04
CA1341064C (en) 2000-08-01
EP0243645B1 (de) 1994-03-16
DK172221B1 (da) 1998-01-12
HU202118B (en) 1991-02-28
HU896609D0 (en) 1990-02-28
AU7064987A (en) 1987-10-01
NZ219764A (en) 1990-11-27
EG18175A (en) 1994-07-30
DD280765A5 (de) 1990-07-18
KR870008841A (ko) 1987-10-21
PT84564B (pt) 1989-11-10
FI871304A0 (fi) 1987-03-25
DE3610391A1 (de) 1987-10-08
CS212687A3 (en) 1992-04-15
AU621278B2 (en) 1992-03-12
NO871282L (no) 1987-09-28
FI91876C (fi) 1994-08-25
NO178546C (no) 1996-04-17
IE870784L (en) 1987-09-27

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Legal Events

Date Code Title Description
HPC4 Succession in title of patentee

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH, DE