HUT34024A - Process for preparing ergoline derivatives and pharmaceut compositions containing thereof as active substances - Google Patents

Process for preparing ergoline derivatives and pharmaceut compositions containing thereof as active substances

Info

Publication number
HUT34024A
HUT34024A HU841656A HU165684A HUT34024A HU T34024 A HUT34024 A HU T34024A HU 841656 A HU841656 A HU 841656A HU 165684 A HU165684 A HU 165684A HU T34024 A HUT34024 A HU T34024A
Authority
HU
Hungary
Prior art keywords
pharmaceut
compositions containing
active substances
ergoline derivatives
preparing
Prior art date
Application number
HU841656A
Other languages
English (en)
Other versions
HU198713B (en
Inventor
Luigi Bernardi
Laura Chiodini
Sergio Mantegani
Aldemio Temperilli
Daniela Ruggieri
Patricia Salvati
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838311679A external-priority patent/GB8311679D0/en
Priority claimed from GB838314816A external-priority patent/GB8314816D0/en
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of HUT34024A publication Critical patent/HUT34024A/hu
Publication of HU198713B publication Critical patent/HU198713B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU841656A 1983-04-28 1984-04-27 Process for producing ergolin derivatives and pharmaceutical compositions containing them as active components HU198713B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838311679A GB8311679D0 (en) 1983-04-28 1983-04-28 Ergoline derivatives
GB838314816A GB8314816D0 (en) 1983-05-27 1983-05-27 Ergoline derivatives

Publications (2)

Publication Number Publication Date
HUT34024A true HUT34024A (en) 1985-01-28
HU198713B HU198713B (en) 1989-11-28

Family

ID=26285978

Family Applications (1)

Application Number Title Priority Date Filing Date
HU841656A HU198713B (en) 1983-04-28 1984-04-27 Process for producing ergolin derivatives and pharmaceutical compositions containing them as active components

Country Status (18)

Country Link
US (1) US4690929A (hu)
EP (1) EP0126968B1 (hu)
KR (1) KR900008696B1 (hu)
AU (1) AU556968B2 (hu)
CA (1) CA1205801A (hu)
DE (1) DE3475709D1 (hu)
DK (1) DK162996C (hu)
ES (1) ES531906A0 (hu)
FI (1) FI81349C (hu)
GR (1) GR79575B (hu)
HU (1) HU198713B (hu)
IE (1) IE57240B1 (hu)
IL (1) IL71633A (hu)
NO (1) NO161562C (hu)
PH (1) PH21123A (hu)
PT (1) PT78496B (hu)
SU (1) SU1327788A3 (hu)
YU (1) YU43357B (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714767D0 (en) * 1987-06-24 1987-07-29 Erba Farmitalia Egoline derivatives
NL8400333A (nl) * 1983-02-16 1984-09-17 Sandoz Ag Moederkoornalkaloiden, hun bereiding en hun toepassing.
GB8501078D0 (en) * 1985-01-16 1985-02-20 Erba Farmitalia Piperazin-1-yl-ergo-line derivatives
GB2173189B (en) * 1985-02-21 1988-04-27 Maruko Pharmaceutical Co Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB8515528D0 (en) * 1985-06-19 1985-07-24 Erba Farmitalia Ergoline derivatives
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
DE3528576A1 (de) * 1985-08-06 1987-02-19 Schering Ag Verfahren zur herstellung von ergolin-thioharnstoffen
DE3535929A1 (de) * 1985-10-04 1987-04-09 Schering Ag 1,2-disubstituierte ergolinderivate
GB8617907D0 (en) * 1986-07-22 1986-08-28 Erba Farmitalia Tetracyclic indole derivatives
GB8702364D0 (en) * 1987-02-03 1987-03-11 Erba Farmitalia Ergolinyl heterocycles
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
EP0464178B1 (en) * 1990-01-25 1995-12-06 PHARMACIA S.p.A. Process for preparing ergoline derivatives
GB9006772D0 (en) * 1990-03-27 1990-05-23 Erba Carlo Spa 4-piperidinyl-ergoline derivatives
ATE204278T1 (de) * 1992-12-24 2001-09-15 Pharmacia & Upjohn Spa Serotoninergische ergolin derivate
JP3996897B2 (ja) 2001-06-08 2007-10-24 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス ソマトスタチン−ドーパミンキメラ類似体
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物
CN104768565B (zh) 2012-11-01 2017-04-26 益普生制药股份有限公司 促生长素抑制素类似物及其二聚体

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE622316A (hu) * 1961-09-11
DK140596B (da) * 1971-05-19 1979-10-08 Sandoz Ag Analogifremgangsmåde til fremstilling af 8beta-(ureidomethyl)-ergolenderivater.
US3996228A (en) * 1973-12-21 1976-12-07 Societa' Farmaceutici Italia S.P.A. Pyrimidinoaminoethyl ergoline derivatives
NL7416120A (nl) * 1973-12-21 1975-06-24 Farmaceutici Italia Werkwijze voor het bereiden van pyrimidinoami- nomethylergolinederivaten.
DE2456930A1 (de) * 1974-12-02 1976-08-12 Tesch Kg E Elektronisches zeitspeicherrelais
CH615181A5 (en) * 1975-05-21 1980-01-15 Sandoz Ag Process for the preparation of novel ergolene derivatives
GB2056437A (en) * 1979-08-07 1981-03-18 Erba Farmitalia Secoergoline derivatives
DE3001752A1 (de) * 1980-01-16 1981-07-30 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur herstellung von 8(alpha)-substituierten 6-methylergolinen
DD154897A1 (de) * 1980-12-02 1982-04-28 Seifert Karlheinz Dipl Chem Dr Verfahren zur herstellung von 8-substituierten ergolinen
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
GB2112382B (en) * 1981-11-06 1985-03-06 Erba Farmitalia Ergoline derivatives

Also Published As

Publication number Publication date
EP0126968B1 (en) 1988-12-21
FI81349C (fi) 1990-10-10
IL71633A (en) 1987-12-20
NO161562B (no) 1989-05-22
YU74284A (en) 1986-10-31
EP0126968A1 (en) 1984-12-05
NO841657L (no) 1984-10-29
YU43357B (en) 1989-06-30
HU198713B (en) 1989-11-28
ES8506031A1 (es) 1985-06-01
DK212784A (da) 1984-10-29
FI841631A7 (hu) 1984-10-29
IE57240B1 (en) 1992-06-17
PT78496A (en) 1984-05-01
US4690929A (en) 1987-09-01
SU1327788A3 (ru) 1987-07-30
DK162996B (da) 1992-01-06
PT78496B (en) 1986-07-22
FI841631A0 (hu) 1984-04-25
AU2742184A (en) 1984-11-01
DE3475709D1 (en) 1989-01-26
ES531906A0 (es) 1985-06-01
AU556968B2 (en) 1986-11-27
KR840008353A (ko) 1984-12-14
IL71633A0 (en) 1984-07-31
GR79575B (hu) 1984-10-30
CA1205801A (en) 1986-06-10
PH21123A (en) 1987-07-27
NO161562C (no) 1989-08-30
DK212784D0 (da) 1984-04-27
DK162996C (da) 1992-06-01
KR900008696B1 (ko) 1990-11-27
FI81349B (fi) 1990-06-29

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee