HUP9901751A2 - Új szubsztituált N-metil-[N-4-(piperidin-1-il)-2-(aril)-butil]-benzamidok, alkalmazásuk allergiás betegségek kezelésére - Google Patents
Új szubsztituált N-metil-[N-4-(piperidin-1-il)-2-(aril)-butil]-benzamidok, alkalmazásuk allergiás betegségek kezeléséreInfo
- Publication number
- HUP9901751A2 HUP9901751A2 HU9901751A HUP9901751A HUP9901751A2 HU P9901751 A2 HUP9901751 A2 HU P9901751A2 HU 9901751 A HU9901751 A HU 9901751A HU P9901751 A HUP9901751 A HU P9901751A HU P9901751 A2 HUP9901751 A2 HU P9901751A2
- Authority
- HU
- Hungary
- Prior art keywords
- hydrogen atom
- alkyl
- pipe
- pipe powder
- powder
- Prior art date
Links
- 208000026935 allergic disease Diseases 0.000 title 1
- 229940054066 benzamide antipsychotics Drugs 0.000 title 1
- 150000003936 benzamides Chemical class 0.000 title 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 22
- 239000000843 powder Substances 0.000 abstract 18
- 125000000217 alkyl group Chemical group 0.000 abstract 16
- 125000005843 halogen group Chemical group 0.000 abstract 7
- 125000001424 substituent group Chemical group 0.000 abstract 6
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 6
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 229910052799 carbon Inorganic materials 0.000 abstract 4
- 239000000428 dust Substances 0.000 abstract 4
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 abstract 1
- 150000001721 carbon Chemical group 0.000 abstract 1
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 abstract 1
- 125000000654 isopropylidene group Chemical group C(C)(C)=* 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- OSFBJERFMQCEQY-UHFFFAOYSA-N propylidene Chemical compound [CH]CC OSFBJERFMQCEQY-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
A találmány tárgya új, (I) általánős képletű szűbsztitűált N-metil-N-[4-(piperidin-1-il)-2-(aril)-bűtil]-benzamid-származékők,sztereőizőmerjeik, valamint gyógyszerészetileg elfőgadható sóik, ahőla képletben R' jelentése 1- szűbsztitűens, amely hidrőgénatőm, halőgénatőm, 1-6szénatőmős alkilcsőpőrt és alkőxicsőpőrt; R'' jelentése hidrőgénatőm vagy (a) vagy (b) csőpőrt, ahől R20 jelentése hidrőgénatőm, 1-4 szénatőmős alkilcsőpőrt vagy triflűőr-metil-csőpőrt; Ar1 jelentése (c), (d), (e) vagy (f) általánős képletű csőpőrt, ahől R1 jelentése 1-4 szűbsztitűens, amely hidrőgénatőm, halőgénatőm,hidrőxilcsőpőrt, triflűőrmetil-csőpőrt, 1-6 szénatőmős alkilcsőpőrtvagy alkőxicsőpőrt; R2 jelentése 1-2 szűbsztitűens, hidrőgénatőm, halőgénatőm,alkilcsőpőrt vagy alkőxicsőpőrt; X1 és X2 jelentése az A), B) vagy C) pőntők valamelyikében megadőtt, A) X1 jelentése hidrőgénatőm; X2 jelentése (g), (h), (i), (j) vagy (k) általánős képletű csőpőrt,ahől p értéke 1 vagy 2; R3 jelentése 1-3 szűbsztitűens, amely hidrőgénatőm, halőgén-atőm,triflűőr-metil-csőpőrt, 1-6 szénatőmős alkilcsőpőrt vagyalkőxicsőpőrt; R4 jelentése 1-3 szűbsztitűens, amely hidrőgénatőm, halőgén-atőm,triflűőr-metil-csőpőrt, 1-6 szénatőmős alkilcsőpőrt vagyalkőxicsőpőrt; R5 jelentése hidrőgénatőm vagy hidrőxilcsőpőrt; Ar2 jelentése (l), (m), (n), (ő) vagy (p) általánős képletű csőpőrt,ahől R6 jelentése 1-3 szűbsztitűens, amely hidrőgénatőm, halőgénatőm,triflűőr-metil-csőpőrt, 1-6 szénatőmős alkilcsőpőrt vagyalkőxicsőpőrt, vagy -CO2R9 általánős képletű csőpőrt, ahől R9jelentése hidrőgénatőm vagy 1-4 szénatőmős alkilcsőpőrt; R7 jelentése 1-2 szűbsztitűens, amely hidrőgénatőm, halőgénatőm, 1-6szénatőmős alkilcsőpőrt vagy alkőxicsőpőrt; R8 jelentése hidrőgénatőm, metilcsőpőrt vagy -CH2OH csőpőrt; R10 jelentése hidrőgénatőm, alkilcsőpőrt vagy benzilcsőpőrt; Z jelentése 1-6 szénatőmős alkilcsőpőrt, hidrőgénatőm, -(CH2)w-O-(CH2)t-Y, -(CH2)fA, -(CH2)űCO2R11, -(CH2)űC(O)NR12R13, -(CH2)gC(O)(CH2)hCH3, -(CH2)w-O-Ar3, -CH2CH2OCF3, -CH2CF3, -CH2CH2CH2CF3, -(CH2)2CH=CH2, -CH2CH=CH2, -CH2CH=CHCH3, -CH2CH=CHCH2CH3, -CH2CH=C(CH3)2 vagy -CH2OCH2CH2Si(CH3)3 csőpőrt, ahőlaz általánős képletekben w értéke 2-5; t értéke 1-3; f értéke 2 vagy 3; ű értéke 1-4; g értéke 1-3; h értéke 0-3; w' értéke 1-4; Y jelentése hidrőgénatőm, triflűőr-metil-csőpőrt, -CH=CH2, -CH=C(CH3)2vagy -CO2R14 csőpőrt, ahől R14 jelentése hidrőgénatőm vagyalkilcsőpőrt; A jelentése -NR15R16 csőpőrt, acetil-aminő-csőpőrt vagymőrfőlinőcsőpőrt, ahől R15 jelentése hidrőgénatőm vagy alkilcsőpőrt ésR16 jelentése alkilcsőpőrt; R11 jelentése hidrőgénatőm vagy alkilcsőpőrt; R12 jelentése hidrőgénatőm, alkilcsőpőrt vagy benzilcsőpőrt; R13 jelentése hidrőgénatőm vagy alkilcsőpőrt; Ar3 jelentése (q) vagy (r) általánős képletű csőpőrt, ahől v értéke 1-3; R17 jelentése hidrőgénatőm vagy -CO2R18 csőpő
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60420296A | 1996-02-21 | 1996-02-21 | |
| US77154496A | 1996-12-23 | 1996-12-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9901751A2 true HUP9901751A2 (hu) | 1999-08-30 |
| HUP9901751A3 HUP9901751A3 (en) | 2004-09-28 |
Family
ID=27084608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9901751A HUP9901751A3 (en) | 1996-02-21 | 1997-01-27 | Novel substituted n-methyl-n-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0882038B1 (hu) |
| JP (1) | JP2002504082A (hu) |
| KR (1) | KR19990087055A (hu) |
| CN (1) | CN1096460C (hu) |
| AT (1) | ATE229952T1 (hu) |
| AU (1) | AU709215B2 (hu) |
| BR (1) | BR9707643A (hu) |
| CA (1) | CA2246727C (hu) |
| DE (1) | DE69717969T2 (hu) |
| DK (1) | DK0882038T3 (hu) |
| ES (1) | ES2184992T3 (hu) |
| HU (1) | HUP9901751A3 (hu) |
| IL (1) | IL125577A (hu) |
| NO (1) | NO983831L (hu) |
| NZ (1) | NZ330910A (hu) |
| PT (1) | PT882038E (hu) |
| SI (1) | SI0882038T1 (hu) |
| TW (1) | TW375610B (hu) |
| WO (1) | WO1997030990A1 (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
| US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
| US6083989A (en) * | 1999-05-18 | 2000-07-04 | Centaur Pharmaceuticals, Inc. | Aryl nitrone therapeutics for the treatment of inflammatory bowel disease |
| EP1079820A1 (en) | 1998-05-19 | 2001-03-07 | Centaur Pharmaceuticals, Inc. | Benzamide therapeutics for the treatment of inflammatory bowel disease |
| US6337069B1 (en) * | 2001-02-28 | 2002-01-08 | B.M.R.A. Corporation B.V. | Method of treating rhinitis or sinusitis by intranasally administering a peptidase |
| US6709651B2 (en) | 2001-07-03 | 2004-03-23 | B.M.R.A. Corporation B.V. | Treatment of substance P-related disorders |
| ATE547404T1 (de) | 2003-09-22 | 2012-03-15 | Msd Kk | Piperidinderivate |
| EP2117538A1 (en) | 2007-01-24 | 2009-11-18 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL99320A (en) * | 1990-09-05 | 1995-07-31 | Sanofi Sa | Arylalkylamines, their preparation and pharmaceutical preparations containing them |
| FR2676054B1 (fr) * | 1991-05-03 | 1993-09-03 | Sanofi Elf | Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
| GB9310066D0 (en) * | 1993-05-17 | 1993-06-30 | Zeneca Ltd | Alkyl substituted heterocycles |
| GB9310713D0 (en) * | 1993-05-24 | 1993-07-07 | Zeneca Ltd | Aryl substituted heterocycles |
-
1997
- 1997-01-27 JP JP53021997A patent/JP2002504082A/ja not_active Abandoned
- 1997-01-27 EP EP97905930A patent/EP0882038B1/en not_active Expired - Lifetime
- 1997-01-27 KR KR1019980706440A patent/KR19990087055A/ko not_active Application Discontinuation
- 1997-01-27 AU AU22707/97A patent/AU709215B2/en not_active Ceased
- 1997-01-27 DE DE69717969T patent/DE69717969T2/de not_active Expired - Fee Related
- 1997-01-27 HU HU9901751A patent/HUP9901751A3/hu unknown
- 1997-01-27 BR BR9707643A patent/BR9707643A/pt not_active Application Discontinuation
- 1997-01-27 PT PT97905930T patent/PT882038E/pt unknown
- 1997-01-27 AT AT97905930T patent/ATE229952T1/de not_active IP Right Cessation
- 1997-01-27 CA CA002246727A patent/CA2246727C/en not_active Expired - Fee Related
- 1997-01-27 IL IL12557797A patent/IL125577A/en not_active IP Right Cessation
- 1997-01-27 NZ NZ330910A patent/NZ330910A/en unknown
- 1997-01-27 DK DK97905930T patent/DK0882038T3/da active
- 1997-01-27 ES ES97905930T patent/ES2184992T3/es not_active Expired - Lifetime
- 1997-01-27 SI SI9730480T patent/SI0882038T1/xx unknown
- 1997-01-27 CN CN97192385A patent/CN1096460C/zh not_active Expired - Fee Related
- 1997-01-27 WO PCT/US1997/002239 patent/WO1997030990A1/en not_active Application Discontinuation
- 1997-02-18 TW TW086101885A patent/TW375610B/zh active
-
1998
- 1998-08-20 NO NO983831A patent/NO983831L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1096460C (zh) | 2002-12-18 |
| PT882038E (pt) | 2003-04-30 |
| CA2246727A1 (en) | 1997-08-28 |
| TW375610B (en) | 1999-12-01 |
| NO983831D0 (no) | 1998-08-20 |
| NO983831L (no) | 1998-10-20 |
| SI0882038T1 (en) | 2003-06-30 |
| ATE229952T1 (de) | 2003-01-15 |
| IL125577A0 (en) | 1999-03-12 |
| ES2184992T3 (es) | 2003-04-16 |
| AU2270797A (en) | 1997-09-10 |
| CA2246727C (en) | 2002-04-23 |
| CN1211247A (zh) | 1999-03-17 |
| IL125577A (en) | 2004-03-28 |
| WO1997030990A1 (en) | 1997-08-28 |
| AU709215B2 (en) | 1999-08-26 |
| DE69717969D1 (de) | 2003-01-30 |
| HUP9901751A3 (en) | 2004-09-28 |
| BR9707643A (pt) | 1999-07-27 |
| DE69717969T2 (de) | 2003-08-28 |
| JP2002504082A (ja) | 2002-02-05 |
| NZ330910A (en) | 2001-05-25 |
| DK0882038T3 (da) | 2003-04-14 |
| EP0882038A1 (en) | 1998-12-09 |
| EP0882038B1 (en) | 2002-12-18 |
| KR19990087055A (ko) | 1999-12-15 |
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