HUP9801941A2 - Kaposi-szarkómához és retroperitoneális fibromatózishoz társuló gamma herpeszvírusok DNS polimeráza - Google Patents
Kaposi-szarkómához és retroperitoneális fibromatózishoz társuló gamma herpeszvírusok DNS polimerázaInfo
- Publication number
- HUP9801941A2 HUP9801941A2 HU9801941A HUP9801941A HUP9801941A2 HU P9801941 A2 HUP9801941 A2 HU P9801941A2 HU 9801941 A HU9801941 A HU 9801941A HU P9801941 A HUP9801941 A HU P9801941A HU P9801941 A2 HUP9801941 A2 HU P9801941A2
- Authority
- HU
- Hungary
- Prior art keywords
- dna polymerase
- kaposi
- sarcoma
- herpes viruses
- viruses associated
- Prior art date
Links
- 102000016928 DNA-directed DNA polymerase Human genes 0.000 title abstract 2
- 108010014303 DNA-directed DNA polymerase Proteins 0.000 title abstract 2
- 208000007766 Kaposi sarcoma Diseases 0.000 title 1
- 206010016629 fibroma Diseases 0.000 title 1
- 206010049444 fibromatosis Diseases 0.000 title 1
- 241001529453 unidentified herpesvirus Species 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 2
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 abstract 1
- 241000288906 Primates Species 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 238000012512 characterization method Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 230000000893 fibroproliferative effect Effects 0.000 abstract 1
- 201000000079 gynecomastia Diseases 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16411—Rhadinovirus, e.g. human herpesvirus 8
- C12N2710/16422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
A találmány tárgya a virőlógia területére esik. A találmányközelebbről a herpeszcsaládba tartőzó vírűsőkra vőnatkőzik. Mégközelebbről, a találmány tárgyát egy DNS pőlimeráz azőnősítása ésjellemzése és alkalmazása képezi egy, a főemlősökben - beleértve azembereket is - előfőrdűló fibrőprőliferációs és neőplaziásállapőtőkkal társűlt vírűsőkból álló alcsaládőn belül. A találmányszerinti DNS pőlimeráz alkalmas mőlekűláris biőlógiai reagenskénttörténő felhasználásra, és alkalmazható diagnősztikűmként is,vírűsfertőzöttség megálapítására. ŕ
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US114895P | 1995-07-14 | 1995-07-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP9801941A2 true HUP9801941A2 (hu) | 1998-11-30 |
Family
ID=21694624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9801941A HUP9801941A2 (hu) | 1995-07-14 | 1996-07-12 | Kaposi-szarkómához és retroperitoneális fibromatózishoz társuló gamma herpeszvírusok DNS polimeráza |
Country Status (12)
Country | Link |
---|---|
US (1) | US5925733A (hu) |
EP (1) | EP0842277A1 (hu) |
JP (1) | JP2002515725A (hu) |
KR (1) | KR19990028971A (hu) |
CN (1) | CN1196089A (hu) |
AU (1) | AU6676496A (hu) |
BR (1) | BR9609713A (hu) |
CA (1) | CA2226872A1 (hu) |
CZ (1) | CZ6098A3 (hu) |
HU (1) | HUP9801941A2 (hu) |
NO (1) | NO980148L (hu) |
WO (1) | WO1997004105A1 (hu) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2001296864A1 (en) | 2000-08-31 | 2002-03-13 | Mayo Foundation For Medical Education And Research | Detection of varicella-zoster virus |
AU2003268107A1 (en) * | 2002-08-14 | 2004-03-03 | The Board Of Regents Of The University Of Texas System | Clinical assays for the detection and typing of human herpesviruses |
GB0313132D0 (en) * | 2003-06-06 | 2003-07-09 | Ich Productions Ltd | Peptide ligands |
US20120082677A1 (en) * | 2010-10-01 | 2012-04-05 | Sherif Salah Abdul Aziz | Compositions for the treatment of hcv and hbv |
WO2014079464A1 (en) * | 2012-11-21 | 2014-05-30 | Sherif Salah Abdul Aziz | A novel enzymes compositions for treatment of human immunodeficiency virus (hiv) infection |
WO2014110127A1 (en) * | 2013-01-08 | 2014-07-17 | Enzo Biochem, Inc. | Diagnosis and treatment of viral diseases |
US9617607B2 (en) | 2013-01-08 | 2017-04-11 | Enzo Biochem, Inc. | Diagnosis and treatment of viral diseases |
CN105392903B (zh) * | 2014-05-02 | 2021-05-04 | 生物辐射实验室股份有限公司 | 预扩增试验 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5244792A (en) * | 1984-04-06 | 1993-09-14 | Chiron Corporation | Expression of recombinant glyoprotein B from herpes simplex virus |
US5171568A (en) * | 1984-04-06 | 1992-12-15 | Chiron Corporation | Recombinant herpes simplex gb-gd vaccine |
US5350671A (en) * | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
CA1335718C (en) * | 1988-04-14 | 1995-05-30 | Mary L. Haffey | Expression of a functional form of a herpes virus dna polymerase in yeast |
US5120639A (en) * | 1989-04-03 | 1992-06-09 | E. R. Squibb & Sons, Inc. | Selective inhibition of dna polymerase |
US5223391A (en) * | 1990-02-21 | 1993-06-29 | President And Fellows Of Harvard College | Inhibitors of herpes simplex virus replication |
JP3167138B2 (ja) * | 1991-02-25 | 2001-05-21 | 株式会社ヤトロン | 単純ヘルペスウイルスの型特異的検出方法 |
-
1996
- 1996-07-11 US US08/680,326 patent/US5925733A/en not_active Expired - Fee Related
- 1996-07-12 HU HU9801941A patent/HUP9801941A2/hu unknown
- 1996-07-12 BR BR9609713-2A patent/BR9609713A/pt not_active Application Discontinuation
- 1996-07-12 KR KR1019980700273A patent/KR19990028971A/ko not_active Application Discontinuation
- 1996-07-12 WO PCT/US1996/011688 patent/WO1997004105A1/en not_active Application Discontinuation
- 1996-07-12 CA CA002226872A patent/CA2226872A1/en not_active Abandoned
- 1996-07-12 AU AU66764/96A patent/AU6676496A/en not_active Abandoned
- 1996-07-12 CN CN96196991A patent/CN1196089A/zh active Pending
- 1996-07-12 JP JP50677797A patent/JP2002515725A/ja active Pending
- 1996-07-12 CZ CZ9860A patent/CZ6098A3/cs unknown
- 1996-07-12 EP EP96926720A patent/EP0842277A1/en not_active Withdrawn
-
1998
- 1998-01-13 NO NO980148A patent/NO980148L/no unknown
Also Published As
Publication number | Publication date |
---|---|
MX9800392A (es) | 1998-09-30 |
CZ6098A3 (cs) | 1998-08-12 |
WO1997004105A1 (en) | 1997-02-06 |
AU6676496A (en) | 1997-02-18 |
KR19990028971A (ko) | 1999-04-15 |
CN1196089A (zh) | 1998-10-14 |
NO980148L (no) | 1998-03-13 |
CA2226872A1 (en) | 1997-02-06 |
EP0842277A1 (en) | 1998-05-20 |
NO980148D0 (no) | 1998-01-13 |
BR9609713A (pt) | 1999-12-21 |
US5925733A (en) | 1999-07-20 |
JP2002515725A (ja) | 2002-05-28 |
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