HUP9701479A3 - N-benzylazolium derivatives containing hydrolysing group, process for their preparation and pharmaceutical compositions containing them - Google Patents
N-benzylazolium derivatives containing hydrolysing group, process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- HUP9701479A3 HUP9701479A3 HU9701479A HUP9701479A HUP9701479A3 HU P9701479 A3 HUP9701479 A3 HU P9701479A3 HU 9701479 A HU9701479 A HU 9701479A HU P9701479 A HUP9701479 A HU P9701479A HU P9701479 A3 HUP9701479 A3 HU P9701479A3
- Authority
- HU
- Hungary
- Prior art keywords
- benzylazolium
- preparation
- group
- pharmaceutical compositions
- hydrolysing
- Prior art date
Links
- FNEQHKCQXDKYEO-UHFFFAOYSA-N 1-benzylpyrrole Chemical class C1=CC=CN1CC1=CC=CC=C1 FNEQHKCQXDKYEO-UHFFFAOYSA-N 0.000 title 1
- 230000003301 hydrolyzing effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96114390 | 1996-09-09 | ||
| EP97114246 | 1997-08-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9701479D0 HU9701479D0 (en) | 1997-10-28 |
| HUP9701479A2 HUP9701479A2 (hu) | 1999-02-01 |
| HUP9701479A3 true HUP9701479A3 (en) | 2001-02-28 |
Family
ID=26142161
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9701479A HUP9701479A3 (en) | 1996-09-09 | 1997-09-05 | N-benzylazolium derivatives containing hydrolysing group, process for their preparation and pharmaceutical compositions containing them |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5900486A (hu) |
| JP (1) | JP2965532B2 (hu) |
| KR (1) | KR100252433B1 (hu) |
| CN (1) | CN1182739A (hu) |
| AU (1) | AU3685097A (hu) |
| CA (1) | CA2214669A1 (hu) |
| CZ (1) | CZ282897A3 (hu) |
| HU (1) | HUP9701479A3 (hu) |
| IL (1) | IL121691A0 (hu) |
| MA (1) | MA26440A1 (hu) |
| NO (1) | NO974125L (hu) |
| NZ (1) | NZ328607A (hu) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999045008A1 (en) | 1998-03-06 | 1999-09-10 | F. Hoffmann-La Roche Ag | 3-[4-(4-cyanophenyl)thiazol-2-y)]-1-(1h-1,2,4-triazol-1-yl)-butan-2-ol derivatives having antifungal activity |
| WO2000030655A1 (en) * | 1998-11-20 | 2000-06-02 | Bristol-Myers Squibb Company | Water soluble prodrugs of azole compounds |
| US6319933B1 (en) | 2000-04-17 | 2001-11-20 | Basilea Pharmaceutica Ag | Azole derivatives |
| CA2822457C (en) | 2001-12-14 | 2016-03-08 | The University Of Wyoming | Methods and compositions for controlled resease of drugs |
| TW200606129A (en) * | 2004-07-26 | 2006-02-16 | Chugai Pharmaceutical Co Ltd | Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same |
| CN101391985B (zh) * | 2007-09-18 | 2013-09-11 | 西南大学 | 具抗微生物活性的三唑鎓类化合物及制备方法和医药用途 |
| CN103857440B (zh) * | 2011-06-22 | 2018-09-25 | 维奥姆生物科学有限公司 | 基于缀合物的抗真菌和抗细菌前药 |
| CN104974143A (zh) * | 2015-05-12 | 2015-10-14 | 深圳致君制药有限公司 | 一种季铵盐类化合物、其制备方法以及用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH468788A (de) * | 1966-04-29 | 1969-02-28 | Basf Ag | Mischung zur Bekämpfung von Algen und Pilzen |
| US4017631A (en) * | 1974-11-19 | 1977-04-12 | Janssen Pharmaceutica N.V. | Imidazolium salts |
| DE2531031C3 (de) * | 1975-07-11 | 1978-03-16 | Schuelke & Mayr Gmbh, 2000 Norderstedt | 1 -Benzyl-3-alkyI-imidazoliumsalze |
| DE2643563A1 (de) * | 1976-09-28 | 1978-03-30 | Bayer Ag | Alpha-(4-biphenylyl)-benzyl-azolium- salze, verfahren zu ihrer herstellung sowie ihre verwendung zur bekaempfung von mikroorganismen |
| DE2714290A1 (de) * | 1977-03-31 | 1978-10-05 | Bayer Ag | Fungizide mittel |
| US4218458A (en) * | 1978-06-23 | 1980-08-19 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of (4-aryloxy-methyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles |
| US4402957A (en) * | 1979-04-04 | 1983-09-06 | Janssen Pharmaceutica N.V. | Heterocyclic derivatives of [4-(piperazin-1-ylphenyloxymethyl)-1,3-dioxolan-2-ylmethyl]-1H-imidazoles and 1H-1,2,4-triazoles |
| FR2486079A1 (fr) * | 1980-07-07 | 1982-01-08 | Rhone Poulenc Agrochimie | Sels quaternaires d'alcoyl-1-imidazolium de l'acide phosphoreux ou ses monoesters, procedes pour les preparer et compositions fongicides les contenant |
| US4490530A (en) * | 1981-01-14 | 1984-12-25 | Janssen Pharmaceutica N.V. | Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)-methyl-1H-imidazoles and 1H-1,2,4-triazoles |
| DE3262386D1 (en) * | 1981-06-06 | 1985-03-28 | Pfizer Ltd | Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them |
| DE3217963A1 (de) * | 1982-05-13 | 1983-11-17 | Basf Ag, 6700 Ludwigshafen | Dibenzofuranoxyalkyl-imidazoliumsalze, verfahren zu ihrer herstellung und ihre verwendung als mikrozide |
| US4861879A (en) * | 1983-02-28 | 1989-08-29 | Janssen Pharmaceutica N.V. | [[4-[4-Phenyl-1-piperazinyl)phenoxymethyl]-1-3-dioxolan-2-yl]-methyl]-1H-imidazoles and 1H-1,2,4-triazoles |
| DE3319845A1 (de) * | 1983-06-01 | 1984-12-06 | Basf Ag, 6700 Ludwigshafen | Arylalkylimidazolium- und -triazoliumsalze, verfahren zu ihrer herstellung und ihre verwendung als mikrozide |
| US5128351A (en) * | 1990-05-04 | 1992-07-07 | American Cyanamid Company | Bis-aryl amide and urea antagonists of platelet activating factor |
| PT741737E (pt) * | 1994-01-24 | 2000-04-28 | Janssen Pharmaceutica Nv | Antifungicos do tipo azole soluveis em agua |
| NZ270418A (en) * | 1994-02-07 | 1997-09-22 | Eisai Co Ltd | Polycyclic triazole & imidazole derivatives, antifungal compositions |
-
1997
- 1997-08-26 NZ NZ328607A patent/NZ328607A/xx unknown
- 1997-09-03 IL IL12169197A patent/IL121691A0/xx unknown
- 1997-09-04 CA CA002214669A patent/CA2214669A1/en not_active Abandoned
- 1997-09-05 AU AU36850/97A patent/AU3685097A/en not_active Abandoned
- 1997-09-05 HU HU9701479A patent/HUP9701479A3/hu unknown
- 1997-09-08 CN CN97118228A patent/CN1182739A/zh active Pending
- 1997-09-08 NO NO974125A patent/NO974125L/no not_active Application Discontinuation
- 1997-09-08 CZ CZ972828A patent/CZ282897A3/cs unknown
- 1997-09-08 KR KR1019970046176A patent/KR100252433B1/ko not_active IP Right Cessation
- 1997-09-09 JP JP9244252A patent/JP2965532B2/ja not_active Expired - Lifetime
- 1997-09-09 US US08/926,392 patent/US5900486A/en not_active Expired - Fee Related
- 1997-09-09 MA MA24786A patent/MA26440A1/fr unknown
-
1999
- 1999-01-08 US US09/226,987 patent/US5962686A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HU9701479D0 (en) | 1997-10-28 |
| NO974125D0 (no) | 1997-09-08 |
| NO974125L (no) | 1998-03-10 |
| JP2965532B2 (ja) | 1999-10-18 |
| HUP9701479A2 (hu) | 1999-02-01 |
| CZ282897A3 (cs) | 1998-06-17 |
| MA26440A1 (fr) | 2004-12-20 |
| US5962686A (en) | 1999-10-05 |
| KR100252433B1 (ko) | 2000-08-01 |
| NZ328607A (en) | 1999-08-30 |
| KR19980024429A (ko) | 1998-07-06 |
| CN1182739A (zh) | 1998-05-27 |
| AU3685097A (en) | 1998-03-12 |
| IL121691A0 (en) | 1998-02-22 |
| JPH10114758A (ja) | 1998-05-06 |
| CA2214669A1 (en) | 1998-03-09 |
| US5900486A (en) | 1999-05-04 |
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