HUP0500259A2 - Új N-(transz-4-izopropil-ciklohexil-karbonil)-D-fenil-alanin forma, eljárás előállítására és alkalmazása - Google Patents
Új N-(transz-4-izopropil-ciklohexil-karbonil)-D-fenil-alanin forma, eljárás előállítására és alkalmazásaInfo
- Publication number
- HUP0500259A2 HUP0500259A2 HU0500259A HUP0500259A HUP0500259A2 HU P0500259 A2 HUP0500259 A2 HU P0500259A2 HU 0500259 A HU0500259 A HU 0500259A HU P0500259 A HUP0500259 A HU P0500259A HU P0500259 A2 HUP0500259 A2 HU P0500259A2
- Authority
- HU
- Hungary
- Prior art keywords
- phenylalanine
- trans
- isopropylcylohexylcarbonyl
- production
- novel form
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- OELFLUMRDSZNSF-OFLPRAFFSA-N (2R)-2-[[oxo-(4-propan-2-ylcyclohexyl)methyl]amino]-3-phenylpropanoic acid Chemical compound C1CC(C(C)C)CCC1C(=O)N[C@@H](C(O)=O)CC1=CC=CC=C1 OELFLUMRDSZNSF-OFLPRAFFSA-N 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 238000000862 absorption spectrum Methods 0.000 abstract 1
- 238000000634 powder X-ray diffraction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/63—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2002/000114 WO2003093222A1 (en) | 2002-04-29 | 2002-04-29 | Novel form of n-(trans-4-isopropylcyclohexylcarbonyl)-d-phenylalanine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0500259A2 true HUP0500259A2 (hu) | 2005-06-28 |
Family
ID=29287383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0500259A HUP0500259A2 (hu) | 2002-04-29 | 2002-04-29 | Új N-(transz-4-izopropil-ciklohexil-karbonil)-D-fenil-alanin forma, eljárás előállítására és alkalmazása |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7314955B2 (https=) |
| EP (1) | EP1499586A4 (https=) |
| JP (1) | JP4137053B2 (https=) |
| KR (1) | KR20040111490A (https=) |
| AU (1) | AU2002304281A1 (https=) |
| CA (1) | CA2481322A1 (https=) |
| CZ (1) | CZ2004997A3 (https=) |
| HR (1) | HRP20040920A2 (https=) |
| HU (1) | HUP0500259A2 (https=) |
| IL (1) | IL164327A0 (https=) |
| MX (1) | MXNL04000084A (https=) |
| SK (1) | SK287644B6 (https=) |
| WO (1) | WO2003093222A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK287644B6 (sk) | 2002-04-29 | 2011-05-06 | Biocon Limited | Kryštalický N-(trans)-4-izopropylcyklohexylkarbonyl)-D- fenylalanín vo forme C a spôsob jeho prípravy |
| US6861553B2 (en) | 2002-07-03 | 2005-03-01 | Teva Pharmaceuticals Industries Ltd. | Process for preparing nateglinide and intermediates thereof |
| US7534913B2 (en) | 2002-07-18 | 2009-05-19 | Teva Pharmaceutica Industries Ltd. | Crystalline form of nateglinide |
| US7148376B2 (en) | 2002-07-18 | 2006-12-12 | Teva Pharmaceutical Industries Ltd. | Polymorphic forms of nateglinide |
| US7420084B2 (en) * | 2002-07-18 | 2008-09-02 | Teva Pharmaceutical Industries Ltd. | Polymorphic forms of nateglinide |
| US7358390B2 (en) | 2002-07-18 | 2008-04-15 | Teva Pharmaceutical Industries Ltd. | Polymorphic forms of nateglinide |
| WO2004020396A1 (en) * | 2002-08-28 | 2004-03-11 | Dr. Reddy's Laboratories Limited | Crystalline form of nateglinide and process for preparation thereof |
| US7449519B2 (en) * | 2003-02-18 | 2008-11-11 | Konishi Co., Ltd. | Curing resin, method for producing same and curing resin composition |
| HU227073B1 (hu) * | 2003-07-10 | 2010-06-28 | Richter Gedeon Nyrt | Eljárás királisan tiszta N-(transz-4-izopropil-ciklohexilkarbonil)-D-fenil-alanin (nateglinid) és kristálymódosulatainak elõállítására, valamint a G-kristálymódosulata |
| WO2005110395A1 (en) * | 2004-05-19 | 2005-11-24 | University Of South Carolina | System and device for magnetic drug targeting with magnetic drug carrier particles |
| GB0413084D0 (en) * | 2004-06-11 | 2004-07-14 | Cipla Ltd | Process |
| US20100004334A1 (en) * | 2008-07-01 | 2010-01-07 | Mead Johnson Nutrition Company | Nutritional Compositions Containing Punicalagins |
| US11390830B2 (en) | 2018-10-05 | 2022-07-19 | The Chemours Company Fc, Llc | Compositions comprising 1,2-dichloro-1,2-difluoroethylene for use in cleaning and solvent applications |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6354321A (ja) | 1985-03-27 | 1988-03-08 | Ajinomoto Co Inc | 血糖降下剤 |
| US4814684A (en) * | 1987-09-30 | 1989-03-21 | Trw Inc. | Apparatus for extending the Vout/Vin ratio of a DC-to-DC converter |
| US5463116A (en) * | 1991-07-30 | 1995-10-31 | Ajinomoto Co., Inc. | Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them |
| ES2100291T3 (es) | 1991-07-30 | 1997-06-16 | Ajinomoto Kk | Cristales de n-(trans-4-isopropilciclohexilcarbonil)-d-fenilalanina y metodos para prepararlos. |
| SK287644B6 (sk) | 2002-04-29 | 2011-05-06 | Biocon Limited | Kryštalický N-(trans)-4-izopropylcyklohexylkarbonyl)-D- fenylalanín vo forme C a spôsob jeho prípravy |
-
2002
- 2002-04-29 SK SK5005-2004A patent/SK287644B6/sk not_active IP Right Cessation
- 2002-04-29 CZ CZ2004997A patent/CZ2004997A3/cs unknown
- 2002-04-29 MX MXNL04000084A patent/MXNL04000084A/es not_active Application Discontinuation
- 2002-04-29 JP JP2004501362A patent/JP4137053B2/ja not_active Expired - Fee Related
- 2002-04-29 EP EP02733208A patent/EP1499586A4/en not_active Withdrawn
- 2002-04-29 US US10/508,364 patent/US7314955B2/en not_active Expired - Fee Related
- 2002-04-29 AU AU2002304281A patent/AU2002304281A1/en not_active Abandoned
- 2002-04-29 CA CA002481322A patent/CA2481322A1/en not_active Abandoned
- 2002-04-29 HR HR20040920A patent/HRP20040920A2/xx not_active Application Discontinuation
- 2002-04-29 KR KR10-2004-7015883A patent/KR20040111490A/ko not_active Ceased
- 2002-04-29 HU HU0500259A patent/HUP0500259A2/hu unknown
- 2002-04-29 WO PCT/IN2002/000114 patent/WO2003093222A1/en not_active Ceased
-
2004
- 2004-09-28 IL IL16432704A patent/IL164327A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1499586A1 (en) | 2005-01-26 |
| HRP20040920A2 (en) | 2005-02-28 |
| AU2002304281A1 (en) | 2003-11-17 |
| US7314955B2 (en) | 2008-01-01 |
| CA2481322A1 (en) | 2003-11-13 |
| KR20040111490A (ko) | 2004-12-31 |
| IL164327A0 (en) | 2005-12-18 |
| CZ2004997A3 (cs) | 2005-01-12 |
| JP4137053B2 (ja) | 2008-08-20 |
| US20050165108A1 (en) | 2005-07-28 |
| EP1499586A4 (en) | 2006-01-18 |
| SK50052004A3 (sk) | 2005-03-04 |
| MXNL04000084A (es) | 2006-02-28 |
| SK287644B6 (sk) | 2011-05-06 |
| JP2005523933A (ja) | 2005-08-11 |
| WO2003093222A1 (en) | 2003-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |