HUP0401991A2 - Eljárás szubsztituált imidazo[1,2-a]-5,6,7,8-tetrahidropiridin-8-on-származékok előállítására - Google Patents

Eljárás szubsztituált imidazo[1,2-a]-5,6,7,8-tetrahidropiridin-8-on-származékok előállítására

Info

Publication number
HUP0401991A2
HUP0401991A2 HU0401991A HUP0401991A HUP0401991A2 HU P0401991 A2 HUP0401991 A2 HU P0401991A2 HU 0401991 A HU0401991 A HU 0401991A HU P0401991 A HUP0401991 A HU P0401991A HU P0401991 A2 HUP0401991 A2 HU P0401991A2
Authority
HU
Hungary
Prior art keywords
derivatives
general formula
tetrahydropyridine
producing
imidazo
Prior art date
Application number
HU0401991A
Other languages
English (en)
Inventor
Hagen Weigl
Klaus Ebel
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of HUP0401991A2 publication Critical patent/HUP0401991A2/hu
Publication of HUP0401991A3 publication Critical patent/HUP0401991A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány tárgya eljárás (Ia) vagy (Ib) általános képletűimidazo[1,2-a]-5,6,7,8-tetrahidropiridin-8-on-származékokelőállítására, amelynek során a) egy (III) általános képletű g-butirolaktont egy (IIa) vagy (IIb) általános képletű imidazollalreagáltatva, amely legalább egy, hidrogénatomtól eltérő szubsztituensttartalmaz a 4-es vagy 5-ös helyzetben, és b) az imidazo-[1,2-a]-5,6,7,8-tetrahidropiridin-8-ont, izolálják, mely képletekben R1, R2 ésmindegyik R3 jelentése egymástól függetlenül hidrogénatom,szubsztituálatlan, egyenes vagy elágazó vagy ciklikus alkilcsoport,szubsztituált vagy szubsztituálatlan arilcsoport, ahol R3szubsztituensek száma n, melynek értéke 1-3. Ó
HU0401991A 2001-09-14 2002-09-03 Method for producing of substituted imidazo[1,2-a]-5,6,7,8-tetrahydropyridine-8-on derivatives HUP0401991A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10145457A DE10145457A1 (de) 2001-09-14 2001-09-14 Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen
PCT/EP2002/009813 WO2003024963A2 (de) 2001-09-14 2002-09-03 Substituierte imidazo [1, 2-a]-5, 6, 7, 8- tetrahydropyridin-8-one, verfahren zu ihrer herstellung, sowie deren verwendung zur herstellung von imidazo [1, 2-a] pyridinen

Publications (2)

Publication Number Publication Date
HUP0401991A2 true HUP0401991A2 (hu) 2005-01-28
HUP0401991A3 HUP0401991A3 (en) 2005-11-28

Family

ID=7699112

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401991A HUP0401991A3 (en) 2001-09-14 2002-09-03 Method for producing of substituted imidazo[1,2-a]-5,6,7,8-tetrahydropyridine-8-on derivatives

Country Status (7)

Country Link
US (1) US7196196B2 (hu)
EP (1) EP1430052A2 (hu)
JP (1) JP2005504079A (hu)
CA (1) CA2459960A1 (hu)
DE (1) DE10145457A1 (hu)
HU (1) HUP0401991A3 (hu)
WO (1) WO2003024963A2 (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008156314A2 (en) * 2007-06-20 2008-12-24 Lg Electronics Inc. Effective system information reception method
US8687565B2 (en) * 2007-09-20 2014-04-01 Lg Electronics Inc. Method of effectively transmitting radio resource allocation request in mobile communication system
US8992897B2 (en) 2010-01-06 2015-03-31 Elc Management Llc Skin lightening compositions
US8722026B2 (en) * 2010-01-06 2014-05-13 Elc Management, Llc Skin lightening compositions

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166851A (en) 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
ZA81219B (en) 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (en) 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (en) 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
US4831041A (en) 1986-11-26 1989-05-16 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
IL86269A0 (en) 1987-05-08 1988-11-15 Byk Gulden Lomberg Chem Fab Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
AU615666B2 (en) 1987-07-16 1991-10-10 Byk Gulden Lomberg Chemische Fabrik Gmbh New diazols
GB8722488D0 (en) 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound
US5574042A (en) * 1992-11-02 1996-11-12 Fujisawa Pharmaceutical Co., Ltd Imidazo [1,2-a] pyridines and their pharmaceutical use
AU686115B2 (en) 1992-11-02 1998-02-05 Fujisawa Pharmaceutical Co., Ltd. Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation
IL108520A (en) * 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US5426105A (en) 1993-09-24 1995-06-20 G.D. Searle & Co. Conformationally restricted angiotensin II antagonists
UA48122C2 (uk) 1993-10-11 2002-08-15 Бік Гульден Ломберг Хеміше Фабрік Гмбх АЛКОКСІАЛКІЛКАРБАМАТИ ІМІДАЗО[1,2-а]ПІРИДИНІВ, СПОСІБ ЇХ ОДЕРЖАННЯ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ
HU220874B1 (en) 1994-07-28 2002-06-29 Byk Gulden Lomberg Chem Fab Imidazopyridine-azolidinones, process for producing them, the use thereof and pharmaceutical compositions containing them
EP0772614A1 (de) 1994-07-28 1997-05-14 Byk Gulden Lomberg Chemische Fabrik GmbH Halogenimidazopyridine
US6132768A (en) * 1995-07-05 2000-10-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors
JP2000513710A (ja) * 1996-01-26 2000-10-17 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング ３―メチルイミダゾピリジン
DE19602853A1 (de) 1996-01-26 1997-07-31 Byk Gulden Lomberg Chem Fab Neue Halogenimidazopyridine
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
EP0971922B1 (en) 1997-03-24 2004-04-28 ALTANA Pharma AG Tetrahydropyrido compounds
AU736767B2 (en) 1997-05-28 2001-08-02 Altana Pharma Ag Fused dihydropyrans
FR2772267A1 (fr) 1997-12-16 1999-06-18 Oreal Compositions de teinture des fibres keratiniques contenant des derives imidazo-pyridines et procede
BR0109542A (pt) * 2000-03-29 2003-06-10 Altana Pharma Ag Derivados de imidazopirina alquilados
US6653477B2 (en) 2000-03-29 2003-11-25 Altana Pharma Ag Imidazopyridin-8-ones
BR0114873A (pt) 2000-10-25 2003-07-01 Altana Pharma Ag Imidazopiridinas polissubstituìdas
CN1659143A (zh) * 2001-03-01 2005-08-24 盐野义制药株式会社 具有hiv整合酶抑制活性的含氮杂芳基化合物

Also Published As

Publication number Publication date
US20050020620A1 (en) 2005-01-27
EP1430052A2 (de) 2004-06-23
JP2005504079A (ja) 2005-02-10
US7196196B2 (en) 2007-03-27
CA2459960A1 (en) 2003-03-27
DE10145457A1 (de) 2003-04-03
HUP0401991A3 (en) 2005-11-28
WO2003024963A3 (de) 2003-09-12
WO2003024963A2 (de) 2003-03-27

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Legal Events

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