WO2003024963A3 - Substituierte imidazo [1, 2-a]-5, 6, 7, 8- tetrahydropyridin-8-one, verfahren zu ihrer herstellung, sowie deren verwendung zur herstellung von imidazo [1, 2-a] pyridinen - Google Patents

Substituierte imidazo [1, 2-a]-5, 6, 7, 8- tetrahydropyridin-8-one, verfahren zu ihrer herstellung, sowie deren verwendung zur herstellung von imidazo [1, 2-a] pyridinen Download PDF

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Publication number
WO2003024963A3
WO2003024963A3 PCT/EP2002/009813 EP0209813W WO03024963A3 WO 2003024963 A3 WO2003024963 A3 WO 2003024963A3 EP 0209813 W EP0209813 W EP 0209813W WO 03024963 A3 WO03024963 A3 WO 03024963A3
Authority
WO
WIPO (PCT)
Prior art keywords
imidazo
tetrahydropyridine
ones
pyridines
producing
Prior art date
Application number
PCT/EP2002/009813
Other languages
English (en)
French (fr)
Other versions
WO2003024963A2 (de
Inventor
Hagen Weigl
Klaus Ebel
Original Assignee
Basf Ag
Hagen Weigl
Klaus Ebel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag, Hagen Weigl, Klaus Ebel filed Critical Basf Ag
Priority to EP02776963A priority Critical patent/EP1430052A2/de
Priority to US10/488,751 priority patent/US7196196B2/en
Priority to JP2003528810A priority patent/JP2005504079A/ja
Priority to HU0401991A priority patent/HUP0401991A3/hu
Priority to CA002459960A priority patent/CA2459960A1/en
Publication of WO2003024963A2 publication Critical patent/WO2003024963A2/de
Publication of WO2003024963A3 publication Critical patent/WO2003024963A3/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Die Erfindung betrifft Verfahren zur Herstellung von Imidazo-[1m 2-a]-5,6,7,8-tetrahydropyridin-8-one durch Umsetzung von Ϝ-Butyrolactonen mit Imidazolen, neue Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, sowie deren Verwendung zur Herstellung von Imidazo[1,2-a]pyridinen.
PCT/EP2002/009813 2001-09-14 2002-09-03 Substituierte imidazo [1, 2-a]-5, 6, 7, 8- tetrahydropyridin-8-one, verfahren zu ihrer herstellung, sowie deren verwendung zur herstellung von imidazo [1, 2-a] pyridinen WO2003024963A2 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP02776963A EP1430052A2 (de) 2001-09-14 2002-09-03 SUBSTITUIERTE IMIDAZO 1, 2−A −5&comm a; 6, 7, 8− TETRAHYDROPYRIDIN−8−ONE, VERFAHREN ZU IHRER HERSTELLUNG, SOWIE DEREN VERWENDUNG ZUR HERSTELLUNG VON IMIDAZO 1, 2−A PY RIDINEN
US10/488,751 US7196196B2 (en) 2001-09-14 2002-09-03 Substituted imidazo[1, 2-a]-5,6,7,8-tetrahydropyridine-8-ones, method for their production and the use thereof for producing imidazo[1,2-a]pyridines
JP2003528810A JP2005504079A (ja) 2001-09-14 2002-09-03 γ−ブチロラクトンとイミダゾールとの反応によるイミダゾ−［１，２−ａ］−５，６，７，８−テトラヒドロピリジン−８−オンの製造法、新規のイミダゾ−［１，２−ａ］−５，６，７，８−テトラヒドロピリジン−８−オン、並びにイミダゾ−［１，２−ａ］ピリジンを製造するためのその使用
HU0401991A HUP0401991A3 (en) 2001-09-14 2002-09-03 Method for producing of substituted imidazo[1,2-a]-5,6,7,8-tetrahydropyridine-8-on derivatives
CA002459960A CA2459960A1 (en) 2001-09-14 2002-09-03 Substituted imidazo[1, 2-a]-5, 6, 7,8-tetrahydropyridine-8-ones, method for their production and the use thereof for producing imidazo[1, 2-a]pyridines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10145457.0 2001-09-14
DE10145457A DE10145457A1 (de) 2001-09-14 2001-09-14 Substituierte Imidazo[1,2-a]-5,6,7,8-tetrahydropyridin-8-one, Verfahren zu ihrer Herstellung, sowie deren Verwendung zur Herstellung von Imidazo[1,2,-a]pyridinen

Publications (2)

Publication Number Publication Date
WO2003024963A2 WO2003024963A2 (de) 2003-03-27
WO2003024963A3 true WO2003024963A3 (de) 2003-09-12

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/009813 WO2003024963A2 (de) 2001-09-14 2002-09-03 Substituierte imidazo [1, 2-a]-5, 6, 7, 8- tetrahydropyridin-8-one, verfahren zu ihrer herstellung, sowie deren verwendung zur herstellung von imidazo [1, 2-a] pyridinen

Country Status (7)

Country Link
US (1) US7196196B2 (de)
EP (1) EP1430052A2 (de)
JP (1) JP2005504079A (de)
CA (1) CA2459960A1 (de)
DE (1) DE10145457A1 (de)
HU (1) HUP0401991A3 (de)
WO (1) WO2003024963A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008156314A2 (en) * 2007-06-20 2008-12-24 Lg Electronics Inc. Effective system information reception method
WO2009038377A2 (en) * 2007-09-20 2009-03-26 Lg Electronics Inc. Method of effectively transmitting radio resource allocation request in mobile communication system
US8992897B2 (en) 2010-01-06 2015-03-31 Elc Management Llc Skin lightening compositions
US8722026B2 (en) * 2010-01-06 2014-05-13 Elc Management, Llc Skin lightening compositions

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426105A (en) * 1993-09-24 1995-06-20 G.D. Searle & Co. Conformationally restricted angiotensin II antagonists
WO1998042707A1 (en) * 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
WO2001072748A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Imidazopyridin-8-ones
WO2001072754A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Alkylated imidazopyridine derivatives
WO2002034749A1 (en) * 2000-10-25 2002-05-02 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors
WO2002070486A1 (fr) * 2001-03-01 2002-09-12 Shionogi & Co., Ltd. Composes d'heteroaryle azote exerçant un effet inhibiteur sur l'integrase du vih

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166851A (en) 1977-05-16 1979-09-04 Merck & Co., Inc. Certain imidazo(1,2a)pyridine derivatives
ZA81219B (en) 1980-01-23 1982-01-27 Schering Corp Imidazo (1,2-a) pyridines ,process for their preparation and pharmaceutical compositions containing them
EP0068378B1 (de) 1981-06-26 1986-03-05 Schering Corporation Imidazo(1,2-a)pyridine und -pyrazine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4725601A (en) 1985-06-04 1988-02-16 Fujisawa Pharmaceutical Co., Ltd. Certain imidazo[1,2-a]pyridines useful in the treatment of ulcers
EP0228006A1 (de) 1985-12-16 1987-07-08 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridinverbindungen und Verfahren zu ihrer Herstellung
US4831041A (en) 1986-11-26 1989-05-16 Fujisawa Pharmaceutical Co., Ltd. Imidazopyridine compounds and processes for preparation thereof
IL86269A0 (en) 1987-05-08 1988-11-15 Byk Gulden Lomberg Chem Fab Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
PT87988B (pt) 1987-07-16 1995-05-04 Byk Gulden Lomberg Chem Fab Processo para a preparacao de diazois e de composicoes farmaceuticas que os contem
GB8722488D0 (en) 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound
AU686115B2 (en) 1992-11-02 1998-02-05 Fujisawa Pharmaceutical Co., Ltd. Imidazo (I,2-a) pyridine derivatives as bradykinin antagonists, pharmaceuticals and processes for their preparation
US5574042A (en) * 1992-11-02 1996-11-12 Fujisawa Pharmaceutical Co., Ltd Imidazo [1,2-a] pyridines and their pharmaceutical use
IL108520A (en) 1993-02-15 1997-09-30 Byk Gulden Lomberg Chem Fab 2, 3, 8-TRISUBSTITUTED IMIDAZO £1, 2-a| PYRIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
UA48122C2 (uk) 1993-10-11 2002-08-15 Бік Гульден Ломберг Хеміше Фабрік Гмбх АЛКОКСІАЛКІЛКАРБАМАТИ ІМІДАЗО[1,2-а]ПІРИДИНІВ, СПОСІБ ЇХ ОДЕРЖАННЯ ТА ЛІКАРСЬКИЙ ЗАСІБ НА ЇХ ОСНОВІ
ATE215084T1 (de) * 1994-07-28 2002-04-15 Byk Gulden Lomberg Chem Fab Imidazopyridin-azolidinone
CA2196075A1 (en) 1994-07-28 1996-02-08 Gerhard Grundler Halogenated imidazopyridines
US6132768A (en) * 1995-07-05 2000-10-17 Byk Gulden Lomberg Chemische Fabrik Gmbh Oral pharmaceutical composition with delayed release of active ingredient for reversible proton pump inhibitors
JP2000513710A (ja) * 1996-01-26 2000-10-17 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング ３―メチルイミダゾピリジン
DE19602853A1 (de) 1996-01-26 1997-07-31 Byk Gulden Lomberg Chem Fab Neue Halogenimidazopyridine
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
BR9809185A (pt) 1997-05-28 2000-08-01 Byk Gulden Lomber Chem Fab Gmb Diidropiranos fundidos
FR2772267A1 (fr) 1997-12-16 1999-06-18 Oreal Compositions de teinture des fibres keratiniques contenant des derives imidazo-pyridines et procede

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5426105A (en) * 1993-09-24 1995-06-20 G.D. Searle & Co. Conformationally restricted angiotensin II antagonists
WO1998042707A1 (en) * 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
WO2001072748A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Imidazopyridin-8-ones
WO2001072754A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Alkylated imidazopyridine derivatives
WO2002034749A1 (en) * 2000-10-25 2002-05-02 Altana Pharma Ag Polysubstituted imidazopyridines as gastric secretion inhibitors
WO2002070486A1 (fr) * 2001-03-01 2002-09-12 Shionogi & Co., Ltd. Composes d'heteroaryle azote exerçant un effet inhibiteur sur l'integrase du vih

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BOND ET AL., J.CHEM.SOC.PERKIN TRANS.I, vol. 19, 1993, pages 2241 - 2242 *
DATABASE CROSSFIRE BEILSTEIN [online] Beilstein Institut zur Foerderung der chemischen Wissenschaften, Frankfurt am Main, De; XP002222931, Database accession no. 5848736 (Citation No) *
DATABASE CROSSFIRE BEILSTEIN [online] Beilstein Institut zur Foerderung der chemischen Wissenschaften, Frankfurt am Main, DE; XP002222932, Database accession no. 3229981 (Reaction ID) *
DATABASE CROSSFIRE BEILSTEIN [online] Beilstein Institut zur Foerderung der chemischen Wissenschaften, Frankfurt am Main, DE; XP002222933, Database accession no. 3144891 (Reaction ID) *
FUKUDA ET AL., CHEM.PHARM.BULL., vol. 28, no. 6, 1980, pages 1667-172 *
HAFENBRADL ET AL.: "Sibyllimycine, ....", ANGEW.CHEM.INT.ED.ENGL., vol. 35, no. 5, 1996, pages 545 - 547, XP002222930 *
KAISER C ET AL: "SYNTHESIS AND ANTIMUSCARINIC PROPERTIES OF SOME N-SUBSTITUTED 5-(AMINOMETHYL)-3,3-DIPENYL-2(3H)-FURANONES", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 35, no. 23, 1992, pages 4415 - 4424, XP002926460, ISSN: 0022-2623 *
SHEVCHENKO ET AL.: "Reaction of Imidazole ...", CHEM.HETEROCYCL.COMPD.(ENGL.TRANSL.), vol. 28, no. 11, 1992, pages 1491 - 1493 *

Also Published As

Publication number Publication date
DE10145457A1 (de) 2003-04-03
JP2005504079A (ja) 2005-02-10
US20050020620A1 (en) 2005-01-27
HUP0401991A3 (en) 2005-11-28
HUP0401991A2 (hu) 2005-01-28
EP1430052A2 (de) 2004-06-23
US7196196B2 (en) 2007-03-27
WO2003024963A2 (de) 2003-03-27
CA2459960A1 (en) 2003-03-27

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