HUP0400368A3 - Oxytocin agonists, pharmaceutical compositions containing them and their use in treatment of sexual dysfunctions - Google Patents
Oxytocin agonists, pharmaceutical compositions containing them and their use in treatment of sexual dysfunctionsInfo
- Publication number
- HUP0400368A3 HUP0400368A3 HU0400368A HUP0400368A HUP0400368A3 HU P0400368 A3 HUP0400368 A3 HU P0400368A3 HU 0400368 A HU0400368 A HU 0400368A HU P0400368 A HUP0400368 A HU P0400368A HU P0400368 A3 HUP0400368 A3 HU P0400368A3
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- pharmaceutical compositions
- compositions containing
- sexual dysfunctions
- oxytocin agonists
- Prior art date
Links
- XNOPRXBHLZRZKH-UHFFFAOYSA-N Oxytocin Natural products N1C(=O)C(N)CSSCC(C(=O)N2C(CCC2)C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(C(C)CC)NC(=O)C1CC1=CC=C(O)C=C1 XNOPRXBHLZRZKH-UHFFFAOYSA-N 0.000 title 1
- 101800000989 Oxytocin Proteins 0.000 title 1
- 102100031951 Oxytocin-neurophysin 1 Human genes 0.000 title 1
- 201000001880 Sexual dysfunction Diseases 0.000 title 1
- 239000000556 agonist Substances 0.000 title 1
- XNOPRXBHLZRZKH-DSZYJQQASA-N oxytocin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@H](N)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 XNOPRXBHLZRZKH-DSZYJQQASA-N 0.000 title 1
- 229960001723 oxytocin Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 231100000872 sexual dysfunction Toxicity 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Tea And Coffee (AREA)
- Current-Collector Devices For Electrically Propelled Vehicles (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0115515.9A GB0115515D0 (en) | 2001-06-25 | 2001-06-25 | Oxytocin agonisys |
| PCT/GB2002/002872 WO2003000692A2 (en) | 2001-06-25 | 2002-06-24 | Oxytocin agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0400368A2 HUP0400368A2 (hu) | 2004-08-30 |
| HUP0400368A3 true HUP0400368A3 (en) | 2007-05-29 |
Family
ID=9917320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0400368A HUP0400368A3 (en) | 2001-06-25 | 2002-06-24 | Oxytocin agonists, pharmaceutical compositions containing them and their use in treatment of sexual dysfunctions |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20040235753A1 (hu) |
| EP (1) | EP1399436B1 (hu) |
| JP (1) | JP2005500317A (hu) |
| KR (1) | KR20040010762A (hu) |
| CN (1) | CN1606553A (hu) |
| AT (1) | ATE291021T1 (hu) |
| CA (1) | CA2450480A1 (hu) |
| CZ (1) | CZ20033414A3 (hu) |
| DE (1) | DE60203290T2 (hu) |
| DK (1) | DK1399436T3 (hu) |
| ES (1) | ES2239717T3 (hu) |
| GB (1) | GB0115515D0 (hu) |
| HK (1) | HK1064666A1 (hu) |
| HU (1) | HUP0400368A3 (hu) |
| IL (1) | IL159289A0 (hu) |
| MX (1) | MXPA03011980A (hu) |
| NO (1) | NO20035772L (hu) |
| NZ (1) | NZ530035A (hu) |
| PL (1) | PL367538A1 (hu) |
| PT (1) | PT1399436E (hu) |
| RU (1) | RU2309156C2 (hu) |
| WO (1) | WO2003000692A2 (hu) |
| ZA (1) | ZA200309626B (hu) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4179782B2 (ja) | 2000-04-26 | 2008-11-12 | 富士通株式会社 | 無線受信装置及び無線通信システム |
| AU2003211011A1 (en) | 2002-02-27 | 2003-09-09 | Ferring Bv | Intermediates and methods for making heptapeptide oxytocin analogues |
| EP1449844A1 (en) | 2003-02-14 | 2004-08-25 | Ferring B.V. | benzamide derivatives as oxytocin agonists and vasopressin antagonists |
| EP1512687A1 (en) * | 2003-09-05 | 2005-03-09 | Ferring B.V. | Piperazines as oxytocin agonists |
| EP1632494A1 (en) * | 2004-08-24 | 2006-03-08 | Ferring B.V. | Vasopressin v1a antagonists |
| WO2007050353A2 (en) * | 2005-10-24 | 2007-05-03 | Wyeth | Tricyclic compounds useful as oxytocin receptor agonists |
| MX2009011923A (es) * | 2007-05-10 | 2009-11-18 | Amr Technology Inc | Tetrahidrobenzo-1,4-diazepinas aril- y heteroaril-sustituidas y uso de las mismas para bloquear reabsorcion de norepinefrina, dopamina y serotonina. |
| WO2009000878A1 (en) * | 2007-06-28 | 2008-12-31 | Novartis Ag | Kallikrein 7 modulators |
| RU2010113975A (ru) * | 2007-09-11 | 2011-10-20 | Мондобайотек Лабораториз Аг (Li) | (D-Leu)-ГИСТРЕЛИН В КАЧЕСТВЕ ТЕРАПЕВТИЧЕСКОГО СРЕДСТВА |
| WO2009033724A1 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of c-type natriuretic peptide, alone or incombination with neuropeptide af, as a therapeutic agent |
| EP2187915B1 (en) * | 2007-09-11 | 2011-08-31 | Mondobiotech Laboratories AG | Use of the peptide phpfhlfvy (renin inhibitor) in anti-angiogenic therapy of certain diseases |
| WO2009033820A2 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
| CA2698691A1 (en) * | 2007-09-11 | 2009-03-19 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
| AR068509A1 (es) * | 2007-09-19 | 2009-11-18 | Jerini Ag | Antagosnistas del receptor de bradiquinina b1 |
| WO2011147889A1 (en) | 2010-05-25 | 2011-12-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical composition for the treatment of a feeding disorder with early-onset in a patient |
| GB201105537D0 (en) * | 2011-03-31 | 2011-05-18 | Vantia Ltd | New process |
| CN103159641A (zh) * | 2011-12-14 | 2013-06-19 | 天津泰普药品科技发展有限公司 | 托伐普坦中间体2-甲酸-5-(2-甲基苯甲酰氨基)甲苯的制备方法 |
| WO2016089797A1 (en) | 2014-12-05 | 2016-06-09 | Merck Sharp & Dohme Corp. | Novel tricyclic compounds as inhibitors of mutant idh enzymes |
| ES2932194T3 (es) * | 2015-07-06 | 2023-01-16 | Kinoxis Therapeutics Pty Ltd | Compuestos terapéuticos y composiciones para el tratamiento de trastornos sociales y trastornos por uso de sustancias |
| CN110248944A (zh) | 2016-12-12 | 2019-09-17 | 悉尼大学 | 非肽催产素受体激动剂 |
| KR20170035351A (ko) | 2017-01-06 | 2017-03-30 | 셰플러코리아(유) | 볼베어링용 케이지 |
| US20220288060A1 (en) * | 2019-09-06 | 2022-09-15 | Kinoxis Therapeutics Pty Ltd | Treatment of Opioid Withdrawal |
| EP4378525A1 (en) * | 2022-11-30 | 2024-06-05 | Université de Strasbourg | Non peptidergic agonists of oxytocin receptor |
| EP4378526A1 (en) * | 2022-11-30 | 2024-06-05 | Université de Strasbourg | Non peptidergic agonists of oxytocin receptor |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2665441B1 (fr) * | 1990-07-31 | 1992-12-04 | Sanofi Sa | Derives de la n-sulfonyl indoline, leur preparation, les compositions pharmaceutiques en contenant. |
| EP1149096B1 (en) * | 1999-02-04 | 2002-12-18 | Wyeth | Tricyclic pyridine n-oxides vasopressin agonists |
| GB0000079D0 (en) * | 2000-01-05 | 2000-02-23 | Ferring Bv | Novel antidiuretic agents |
| GB0015601D0 (en) * | 2000-06-26 | 2000-08-16 | Ferring Bv | Novel antidiuretic agents |
-
2001
- 2001-06-25 GB GBGB0115515.9A patent/GB0115515D0/en not_active Ceased
-
2002
- 2002-06-24 IL IL15928902A patent/IL159289A0/xx unknown
- 2002-06-24 KR KR10-2003-7016688A patent/KR20040010762A/ko not_active Application Discontinuation
- 2002-06-24 PT PT02732974T patent/PT1399436E/pt unknown
- 2002-06-24 PL PL02367538A patent/PL367538A1/xx not_active Application Discontinuation
- 2002-06-24 CA CA002450480A patent/CA2450480A1/en not_active Abandoned
- 2002-06-24 JP JP2003507095A patent/JP2005500317A/ja active Pending
- 2002-06-24 CN CNA028125843A patent/CN1606553A/zh active Pending
- 2002-06-24 EP EP02732974A patent/EP1399436B1/en not_active Expired - Lifetime
- 2002-06-24 US US10/482,102 patent/US20040235753A1/en not_active Abandoned
- 2002-06-24 ES ES02732974T patent/ES2239717T3/es not_active Expired - Lifetime
- 2002-06-24 RU RU2003136152/04A patent/RU2309156C2/ru not_active IP Right Cessation
- 2002-06-24 DK DK02732974T patent/DK1399436T3/da active
- 2002-06-24 CZ CZ20033414A patent/CZ20033414A3/cs unknown
- 2002-06-24 DE DE60203290T patent/DE60203290T2/de not_active Expired - Fee Related
- 2002-06-24 HU HU0400368A patent/HUP0400368A3/hu unknown
- 2002-06-24 AT AT02732974T patent/ATE291021T1/de not_active IP Right Cessation
- 2002-06-24 MX MXPA03011980A patent/MXPA03011980A/es active IP Right Grant
- 2002-06-24 NZ NZ530035A patent/NZ530035A/en unknown
- 2002-06-24 WO PCT/GB2002/002872 patent/WO2003000692A2/en active IP Right Grant
-
2003
- 2003-12-11 ZA ZA200309626A patent/ZA200309626B/xx unknown
- 2003-12-22 NO NO20035772A patent/NO20035772L/no not_active Application Discontinuation
-
2004
- 2004-09-23 HK HK04107317A patent/HK1064666A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20040010762A (ko) | 2004-01-31 |
| PL367538A1 (en) | 2005-02-21 |
| ES2239717T3 (es) | 2005-10-01 |
| PT1399436E (pt) | 2005-07-29 |
| EP1399436B1 (en) | 2005-03-16 |
| US20040235753A1 (en) | 2004-11-25 |
| WO2003000692A3 (en) | 2003-05-15 |
| DE60203290T2 (de) | 2006-02-02 |
| RU2003136152A (ru) | 2005-05-20 |
| MXPA03011980A (es) | 2004-03-26 |
| ATE291021T1 (de) | 2005-04-15 |
| CN1606553A (zh) | 2005-04-13 |
| IL159289A0 (en) | 2004-06-01 |
| NZ530035A (en) | 2004-06-25 |
| GB0115515D0 (en) | 2001-08-15 |
| ZA200309626B (en) | 2004-05-12 |
| EP1399436A2 (en) | 2004-03-24 |
| JP2005500317A (ja) | 2005-01-06 |
| WO2003000692A2 (en) | 2003-01-03 |
| RU2309156C2 (ru) | 2007-10-27 |
| HUP0400368A2 (hu) | 2004-08-30 |
| DE60203290D1 (de) | 2005-04-21 |
| CZ20033414A3 (en) | 2004-05-12 |
| DK1399436T3 (da) | 2005-05-30 |
| CA2450480A1 (en) | 2003-01-03 |
| HK1064666A1 (en) | 2005-02-04 |
| NO20035772L (no) | 2003-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |