HUP0303244A2 - Heterokarpin, egy humán GHRH-kötő fehérje - Google Patents
Heterokarpin, egy humán GHRH-kötő fehérjeInfo
- Publication number
- HUP0303244A2 HUP0303244A2 HU0303244A HUP0303244A HUP0303244A2 HU P0303244 A2 HUP0303244 A2 HU P0303244A2 HU 0303244 A HU0303244 A HU 0303244A HU P0303244 A HUP0303244 A HU P0303244A HU P0303244 A2 HUP0303244 A2 HU P0303244A2
- Authority
- HU
- Hungary
- Prior art keywords
- binding protein
- heterocarpine
- ghrh
- human ghrh
- human
- Prior art date
Links
- 102000014914 Carrier Proteins Human genes 0.000 title 1
- 101150102363 Ghrh gene Proteins 0.000 title 1
- 108091008324 binding proteins Proteins 0.000 title 1
- 101710142969 Somatoliberin Proteins 0.000 abstract 2
- 206010000599 Acromegaly Diseases 0.000 abstract 1
- 208000007342 Diabetic Nephropathies Diseases 0.000 abstract 1
- 206010012689 Diabetic retinopathy Diseases 0.000 abstract 1
- 102000038461 Growth Hormone-Releasing Hormone Human genes 0.000 abstract 1
- 239000000095 Growth Hormone-Releasing Hormone Substances 0.000 abstract 1
- 101000825742 Homo sapiens Somatoliberin Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 241001299787 Pilocarpus Species 0.000 abstract 1
- 102100022831 Somatoliberin Human genes 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 208000033679 diabetic kidney disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Botany (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
A találmány tárgya humán GHRH-kötő fehérje (Growth Hormone ReleasingHormone, vagyis növekedési hormont felszabadító hormon). A fehérje,amelyet Pilocarpus heteropryllus növényből állítottak elő,alkalmazható a GHRH hatásait antagonizáló gyógyszerek előállítására,és proliferatív betegségek (különösen rák), akromegália vagydiabéteszes retinopátia és nefropátia kezelésére. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0102631A FR2821359B1 (fr) | 2001-02-27 | 2001-02-27 | L'heterocarpine, une proteine fixant le ghrh humain |
| PCT/FR2002/000691 WO2002068461A2 (fr) | 2001-02-27 | 2002-02-26 | L'heterocarpine, une proteine fixant le ghrh humain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HUP0303244A2 true HUP0303244A2 (hu) | 2003-12-29 |
| HUP0303244A3 HUP0303244A3 (en) | 2005-11-28 |
| HU225431B1 HU225431B1 (en) | 2006-11-28 |
Family
ID=8860481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0303244A HU225431B1 (en) | 2001-02-27 | 2002-02-26 | Heterocarpine, a human ghrh-binding protein |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7385024B2 (hu) |
| EP (1) | EP1409531B1 (hu) |
| JP (1) | JP4117194B2 (hu) |
| KR (1) | KR20030094262A (hu) |
| CN (1) | CN100340573C (hu) |
| AT (1) | ATE309269T1 (hu) |
| AU (1) | AU2002241065B2 (hu) |
| BR (1) | BR0207578A (hu) |
| CA (1) | CA2437516A1 (hu) |
| CZ (1) | CZ20032612A3 (hu) |
| DE (1) | DE60207257T2 (hu) |
| ES (1) | ES2252431T3 (hu) |
| FR (1) | FR2821359B1 (hu) |
| HU (1) | HU225431B1 (hu) |
| IL (2) | IL157150A0 (hu) |
| MX (1) | MXPA03007626A (hu) |
| NZ (1) | NZ527749A (hu) |
| PL (1) | PL207581B1 (hu) |
| RU (1) | RU2305683C2 (hu) |
| WO (1) | WO2002068461A2 (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2843697B1 (fr) * | 2002-08-26 | 2005-12-09 | Sod Conseils Rech Applic | L'heterocarpine, une proteine d'origine vegetale aux proprietes anticancereuses |
| US7494969B2 (en) | 2002-02-26 | 2009-02-24 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Heterocarpine, a plant-derived protein with anti-cancer properties |
| JP2006504694A (ja) * | 2002-09-18 | 2006-02-09 | サントル・オスピタリエ・ドゥ・リュニヴェルシテ・ドゥ・モントリオール・（シー・エイチ・ユー・エム） | Ｇｈｒｈ類似体 |
| FR2848221B1 (fr) * | 2002-12-10 | 2007-09-28 | Sod Conseils Rech Applic | Procede de preparation d'heterocarpine recombinante |
| JP2005289895A (ja) * | 2004-03-31 | 2005-10-20 | Kagoshima Tlo Co Ltd | 植物タンパク質分離精製法及びそれに用いるタンニン中和剤並びにその調製法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5550212A (en) * | 1993-12-17 | 1996-08-27 | The Administrators Of The Tulane Educational Fund | Analogues of hGH-RH(1-29)NH2 having antagonistic activity |
| EP0674007B1 (fr) * | 1994-03-21 | 1999-07-21 | Societe Des Produits Nestle S.A. | Procédé de production de pilocarpine |
| US20050160088A1 (en) | 2001-05-17 | 2005-07-21 | Todd Scallan | System and method for metadata-based distribution of content |
-
2001
- 2001-02-27 FR FR0102631A patent/FR2821359B1/fr not_active Expired - Fee Related
-
2002
- 2002-02-26 AT AT02706900T patent/ATE309269T1/de not_active IP Right Cessation
- 2002-02-26 CN CNB028054660A patent/CN100340573C/zh not_active Expired - Fee Related
- 2002-02-26 CA CA002437516A patent/CA2437516A1/fr not_active Abandoned
- 2002-02-26 EP EP02706900A patent/EP1409531B1/fr not_active Expired - Lifetime
- 2002-02-26 WO PCT/FR2002/000691 patent/WO2002068461A2/fr active IP Right Grant
- 2002-02-26 NZ NZ527749A patent/NZ527749A/en unknown
- 2002-02-26 DE DE60207257T patent/DE60207257T2/de not_active Expired - Lifetime
- 2002-02-26 JP JP2002567971A patent/JP4117194B2/ja not_active Expired - Fee Related
- 2002-02-26 HU HU0303244A patent/HU225431B1/hu not_active IP Right Cessation
- 2002-02-26 PL PL369469A patent/PL207581B1/pl unknown
- 2002-02-26 US US10/470,112 patent/US7385024B2/en not_active Expired - Fee Related
- 2002-02-26 KR KR10-2003-7011194A patent/KR20030094262A/ko not_active Application Discontinuation
- 2002-02-26 IL IL15715002A patent/IL157150A0/xx active IP Right Grant
- 2002-02-26 RU RU2003128963/13A patent/RU2305683C2/ru not_active IP Right Cessation
- 2002-02-26 ES ES02706900T patent/ES2252431T3/es not_active Expired - Lifetime
- 2002-02-26 CZ CZ20032612A patent/CZ20032612A3/cs unknown
- 2002-02-26 MX MXPA03007626A patent/MXPA03007626A/es active IP Right Grant
- 2002-02-26 AU AU2002241065A patent/AU2002241065B2/en not_active Ceased
- 2002-02-26 BR BR0207578-4A patent/BR0207578A/pt not_active Application Discontinuation
-
2003
- 2003-07-29 IL IL157150A patent/IL157150A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1409531B1 (fr) | 2005-11-09 |
| CN1531550A (zh) | 2004-09-22 |
| IL157150A (en) | 2008-11-26 |
| BR0207578A (pt) | 2004-03-02 |
| PL207581B1 (pl) | 2011-01-31 |
| PL369469A1 (en) | 2005-04-18 |
| JP4117194B2 (ja) | 2008-07-16 |
| KR20030094262A (ko) | 2003-12-11 |
| ES2252431T3 (es) | 2006-05-16 |
| ATE309269T1 (de) | 2005-11-15 |
| RU2305683C2 (ru) | 2007-09-10 |
| CZ20032612A3 (cs) | 2004-08-18 |
| JP2004538254A (ja) | 2004-12-24 |
| WO2002068461A2 (fr) | 2002-09-06 |
| RU2003128963A (ru) | 2005-02-20 |
| IL157150A0 (en) | 2004-02-08 |
| AU2002241065B2 (en) | 2006-09-28 |
| FR2821359A1 (fr) | 2002-08-30 |
| FR2821359B1 (fr) | 2003-05-09 |
| HU225431B1 (en) | 2006-11-28 |
| EP1409531A2 (fr) | 2004-04-21 |
| DE60207257D1 (de) | 2005-12-15 |
| US7385024B2 (en) | 2008-06-10 |
| DE60207257T2 (de) | 2006-07-27 |
| CN100340573C (zh) | 2007-10-03 |
| CA2437516A1 (fr) | 2002-09-06 |
| NZ527749A (en) | 2006-09-29 |
| US20040063621A1 (en) | 2004-04-01 |
| WO2002068461A3 (fr) | 2004-02-12 |
| HUP0303244A3 (en) | 2005-11-28 |
| MXPA03007626A (es) | 2003-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC9A | Change of name, address |
Owner name: IPSEN PHARMA S.A.S., FR Free format text: FORMER OWNER(S): SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.), FR |
|
| MM4A | Lapse of definitive patent protection due to non-payment of fees |