HUP0303167A2 - IB-alfa vérlemezke glikoproteinnel képzett fúziós polipeptidek, továbbá eljárások alkalmazásukra - Google Patents

IB-alfa vérlemezke glikoproteinnel képzett fúziós polipeptidek, továbbá eljárások alkalmazásukra

Info

Publication number
HUP0303167A2
HUP0303167A2 HU0303167A HUP0303167A HUP0303167A2 HU P0303167 A2 HUP0303167 A2 HU P0303167A2 HU 0303167 A HU0303167 A HU 0303167A HU P0303167 A HUP0303167 A HU P0303167A HU P0303167 A2 HUP0303167 A2 HU P0303167A2
Authority
HU
Hungary
Prior art keywords
methods
fusion polypeptides
platlet
glycoprotein
alpha fusion
Prior art date
Application number
HU0303167A
Other languages
English (en)
Inventor
Ravindra Kumar
Tom Mcdonagh
Dianne S. Sako
Gray D. Shaw
Francis X. Sullivan
Original Assignee
Genetics Institute, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Institute, Llc filed Critical Genetics Institute, Llc
Publication of HUP0303167A2 publication Critical patent/HUP0303167A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A találmány tárgyát képezik készítmények és eljárások érrendszeribetegségek kezelésére vagy megelőzésére, közelebbről IB-alfavérlemezke glikoproteinek eredetű fúziós polipeptideket tartalmazókészítmények és eljárások ezek alkalmazására. Ó
HU0303167A 2001-02-06 2002-02-06 IB-alfa vérlemezke glikoproteinnel képzett fúziós polipeptidek, továbbá eljárások alkalmazásukra HUP0303167A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26683801P 2001-02-06 2001-02-06
PCT/US2002/003549 WO2002063003A2 (en) 2001-02-06 2002-02-06 Platlet glycoprotein ib alpha fusion polypeptides and methods of use thereof

Publications (1)

Publication Number Publication Date
HUP0303167A2 true HUP0303167A2 (hu) 2003-12-29

Family

ID=23016192

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303167A HUP0303167A2 (hu) 2001-02-06 2002-02-06 IB-alfa vérlemezke glikoproteinnel képzett fúziós polipeptidek, továbbá eljárások alkalmazásukra

Country Status (16)

Country Link
US (5) US6991796B2 (hu)
EP (1) EP1360292A2 (hu)
KR (1) KR20030074796A (hu)
CN (1) CN100523188C (hu)
AR (1) AR035779A1 (hu)
AU (3) AU2002240287B2 (hu)
BR (1) BR0207039A (hu)
CA (1) CA2437714A1 (hu)
HU (1) HUP0303167A2 (hu)
IL (1) IL157264A0 (hu)
MX (1) MXPA03007010A (hu)
NO (1) NO20033474L (hu)
NZ (1) NZ528037A (hu)
PL (1) PL373052A1 (hu)
WO (1) WO2002063003A2 (hu)
ZA (1) ZA200306229B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR035779A1 (es) * 2001-02-06 2004-07-14 Genetics Inst Llc Polipeptidos de fusion derivados de glicoproteina ib alfa de plaqueta y metodos de uso de los mismos
KR20060022261A (ko) 2003-06-11 2006-03-09 와이어쓰 혈소판 당단백질 ｉｂ 알파 변이체 융합 폴리펩티드 및이의 사용 방법
JP2005073528A (ja) * 2003-08-28 2005-03-24 Genetics Inst Llc 生物学的系における生物学的組織への血球の接着を阻害する方法、ならびにその方法に使用するための組成物
CA2564251C (en) * 2004-05-21 2018-04-10 The Uab Research Foundation Variable lymphocyte receptors, related polypeptides and nucleic acids, and uses thereof
US20080015145A1 (en) * 2006-07-11 2008-01-17 Maria Gyongyossy-Issa Mimotope receptors and inhibitors for platelet-platelet and platelet-endothelium interactions
DE102007031708A1 (de) 2007-07-06 2009-01-08 Dade Behring Marburg Gmbh Bestimmung der von Willebrand Faktor-Aktivität in Abwesenheit von Ristocetin
WO2010071934A1 (en) * 2008-12-22 2010-07-01 Baker Idi Heart And Diabetes Institute Holdings Limited Modulation of platelet activation
CN102988983B (zh) * 2011-09-09 2014-06-11 苏州苏大赛尔免疫生物技术有限公司 抗人血小板膜糖蛋白Ibα嵌合抗体药物组合物
CA2871057A1 (en) * 2011-12-23 2013-06-27 Vasculogics, Inc. Compositions and methods for treatment of thrombosis and for prolonging survival of stored platelets
BR112014032254B1 (pt) 2012-06-26 2022-11-01 Ge Healthcare As Processo para a preparação de uma composição, aparelho, e, uso de um aparelho
EP2919013B1 (de) * 2014-03-11 2016-11-02 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Detektion von Modulatoren der GPIb-Thrombin-Interaktion
CN107340225B (zh) * 2017-07-13 2019-07-05 徐州医科大学 一种基于流式细胞术检测血小板受体GPIba胞外段酶切的方法
JP7373993B2 (ja) 2018-02-20 2023-11-06 エフ． ホフマン－ラ ロシュ アーゲー 組換えＧｐＩｂα受容体タンパク質を含む組成物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
US5340727A (en) * 1987-11-17 1994-08-23 The Scripps Research Institute GPIbα fragments and recombinant DNA expression vectors
IL88308A0 (en) 1987-11-17 1989-06-30 Scripps Clinic Res Peptides that block the binding of von willebrand factor
US5225538A (en) 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
US5013556A (en) 1989-10-20 1991-05-07 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5462990A (en) * 1990-10-15 1995-10-31 Board Of Regents, The University Of Texas System Multifunctional organic polymers
US6136310A (en) 1991-07-25 2000-10-24 Idec Pharmaceuticals Corporation Recombinant anti-CD4 antibodies for human therapy
US5317097A (en) * 1991-10-07 1994-05-31 The Research Foundation Of State University Of New York Mutations in the gene encoding the α chain on platelet glycoprotein IB
US6277975B1 (en) * 1992-10-23 2001-08-21 Genetics Institute, Inc. Fusions of P-selectin ligand protein and polynucleotides encoding same
US5516964A (en) 1994-01-21 1996-05-14 Sun Company, Inc. (R&M) Hydrocarbon isomerization using solid superacid catalysts comprising platinum metal
JP3735921B2 (ja) * 1996-02-07 2006-01-18 三菱ウェルファーマ株式会社 ＧＰＩｂ・脂質複合体およびその用途
DK1068241T3 (da) * 1998-04-02 2008-02-04 Genentech Inc Antistofvarianter og fragmenter deraf
ATE417068T1 (de) * 1998-04-23 2008-12-15 Ajinomoto Kk Stoff mit antithrombotischer aktivität und verfahren zur bestimmung von glycokallidin
AR035779A1 (es) * 2001-02-06 2004-07-14 Genetics Inst Llc Polipeptidos de fusion derivados de glicoproteina ib alfa de plaqueta y metodos de uso de los mismos
US6878881B1 (en) * 2004-09-08 2005-04-12 Stephen K. Henry Modular cable protector assembly

Also Published As

Publication number Publication date
US20060093614A1 (en) 2006-05-04
CA2437714A1 (en) 2002-08-15
AR035779A1 (es) 2004-07-14
ZA200306229B (en) 2005-05-26
WO2002063003A2 (en) 2002-08-15
AU2006241373A1 (en) 2006-12-14
IL157264A0 (en) 2004-02-19
WO2002063003A3 (en) 2003-05-15
US20060140935A1 (en) 2006-06-29
US7049128B2 (en) 2006-05-23
NZ528037A (en) 2006-08-31
CN1553955A (zh) 2004-12-08
BR0207039A (pt) 2005-05-03
AU2011200943A1 (en) 2011-03-24
US20030091576A1 (en) 2003-05-15
PL373052A1 (en) 2005-08-08
MXPA03007010A (es) 2004-07-08
AU2002240287B2 (en) 2006-08-24
KR20030074796A (ko) 2003-09-19
EP1360292A2 (en) 2003-11-12
NO20033474L (no) 2003-10-02
NO20033474D0 (no) 2003-08-05
US20090148427A1 (en) 2009-06-11
US6991796B2 (en) 2006-01-31
CN100523188C (zh) 2009-08-05
US20030232047A1 (en) 2003-12-18

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