HUP0301862A3 - Lactam compound, pharmaceutical composition containing it, process for producing it, intermediates and use of it for producing pharmaceutical composition - Google Patents

Lactam compound, pharmaceutical composition containing it, process for producing it, intermediates and use of it for producing pharmaceutical composition

Info

Publication number
HUP0301862A3
HUP0301862A3 HU0301862A HUP0301862A HUP0301862A3 HU P0301862 A3 HUP0301862 A3 HU P0301862A3 HU 0301862 A HU0301862 A HU 0301862A HU P0301862 A HUP0301862 A HU P0301862A HU P0301862 A3 HUP0301862 A3 HU P0301862A3
Authority
HU
Hungary
Prior art keywords
pharmaceutical composition
producing
intermediates
lactam compound
composition containing
Prior art date
Application number
HU0301862A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HUP0301862A2 publication Critical patent/HUP0301862A2/hu
Publication of HUP0301862A3 publication Critical patent/HUP0301862A3/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
HU0301862A 2000-11-17 2001-11-02 Lactam compound, pharmaceutical composition containing it, process for producing it, intermediates and use of it for producing pharmaceutical composition HUP0301862A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24965600P 2000-11-17 2000-11-17
PCT/US2001/027795 WO2002040451A2 (en) 2000-11-17 2001-11-02 Lactam compound

Publications (2)

Publication Number Publication Date
HUP0301862A2 HUP0301862A2 (hu) 2003-09-29
HUP0301862A3 true HUP0301862A3 (en) 2007-09-28

Family

ID=22944436

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0301862A HUP0301862A3 (en) 2000-11-17 2001-11-02 Lactam compound, pharmaceutical composition containing it, process for producing it, intermediates and use of it for producing pharmaceutical composition

Country Status (33)

Country Link
US (1) US20040248878A1 (OSRAM)
EP (1) EP1353910B1 (OSRAM)
JP (1) JP4116431B2 (OSRAM)
KR (1) KR20030045194A (OSRAM)
CN (2) CN101624372A (OSRAM)
AR (1) AR031356A1 (OSRAM)
AT (1) ATE362919T1 (OSRAM)
AU (2) AU2002224321B2 (OSRAM)
BR (1) BR0115424A (OSRAM)
CA (1) CA2425497C (OSRAM)
CY (1) CY1106682T1 (OSRAM)
CZ (1) CZ20031340A3 (OSRAM)
DE (1) DE60128587T2 (OSRAM)
DK (1) DK1353910T3 (OSRAM)
DZ (1) DZ3454A1 (OSRAM)
EA (1) EA006919B1 (OSRAM)
EC (1) ECSP034598A (OSRAM)
ES (1) ES2286162T3 (OSRAM)
HR (1) HRP20030385A2 (OSRAM)
HU (1) HUP0301862A3 (OSRAM)
IL (1) IL155275A0 (OSRAM)
MX (1) MXPA03004250A (OSRAM)
MY (1) MY141607A (OSRAM)
NO (1) NO325217B1 (OSRAM)
PE (1) PE20020798A1 (OSRAM)
PL (1) PL211018B1 (OSRAM)
PT (1) PT1353910E (OSRAM)
SK (1) SK287794B6 (OSRAM)
SV (1) SV2003000741A (OSRAM)
TW (1) TWI235151B (OSRAM)
UA (1) UA77165C2 (OSRAM)
WO (1) WO2002040451A2 (OSRAM)
ZA (1) ZA200303411B (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74849C2 (en) * 2000-11-17 2006-02-15 Lilly Co Eli Lactam
ES2333008T3 (es) 2002-12-20 2010-02-16 Glaxo Group Limited Derivados de benzo(d)azepina para el tratamiento de trastornos neurologicos.
EP1599468B1 (en) 2003-01-14 2007-10-03 Arena Pharmaceuticals, Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
BRPI0610532A2 (pt) 2005-04-08 2010-06-29 Daiichi Sankyo Co Ltd derivado de piridilmetilsulfona
US8258302B2 (en) * 2006-01-31 2012-09-04 Api Corporation Method for producing benzazepinone
TW200920362A (en) 2007-09-11 2009-05-16 Daiichi Sankyo Co Ltd Alkylsulfone derivatives
FR2932800B1 (fr) * 2008-06-20 2015-02-20 Servier Lab Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
AU2011305525B2 (en) 2010-09-22 2016-08-18 Arena Pharmaceuticals, Inc. Modulators of the GPR119 receptor and the treatment of disorders related thereto
KR101899014B1 (ko) 2012-01-06 2018-09-17 삼성전자주식회사 비엘디씨 모터의 제어 장치 및 그 방법
CN102690231B (zh) * 2012-04-11 2014-07-09 南京友杰医药科技有限公司 治疗阿尔茨海默病潜在药物司马西特的合成方法
US20160067306A1 (en) 2013-04-19 2016-03-10 National University Corporation Hokkaido University Treatment agent for cognitive impairment induced by amyloid beta-protein, therapeutic agent for alzheimer's disease, and treatment method and pathological analysis method related to these
CN116850181A (zh) 2015-01-06 2023-10-10 艾尼纳制药公司 治疗与s1p1受体有关的病症的方法
AU2016284162A1 (en) 2015-06-22 2018-02-01 Arena Pharmaceuticals, Inc. Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(Compound1) for use in SIP1 receptor-associated disorders
AU2018220521A1 (en) 2017-02-16 2019-09-05 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
WO2019236757A1 (en) 2018-06-06 2019-12-12 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the s1p1 receptor
IL296723A (en) 2020-03-26 2022-11-01 Seagen Inc Methods of treating multiple myeloma

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL158355A0 (en) * 1996-12-23 2004-05-12 Elan Pharm Inc CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS beta-AMYLOID PEPTIDE RELEASE INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
CA2324474A1 (en) * 1998-06-22 1999-12-29 Elan Pharmaceuticals, Inc. Compounds for inhibiting beta-amyloid peptide release and/or its synthesis
EP1230220A1 (en) * 1999-11-09 2002-08-14 Eli Lilly And Company Beta-aminoacid compounds useful for inhibiting beta-amyloid peptide release and/or its synthesis

Also Published As

Publication number Publication date
MXPA03004250A (es) 2003-09-22
WO2002040451A3 (en) 2003-08-28
AR031356A1 (es) 2003-09-17
CN100516047C (zh) 2009-07-22
JP4116431B2 (ja) 2008-07-09
NO325217B1 (no) 2008-02-25
US20040248878A1 (en) 2004-12-09
ZA200303411B (en) 2004-08-02
CN1575282A (zh) 2005-02-02
NO20032215L (no) 2003-07-16
CN101624372A (zh) 2010-01-13
IL155275A0 (en) 2003-11-23
ES2286162T3 (es) 2007-12-01
CZ20031340A3 (cs) 2004-06-16
PT1353910E (pt) 2007-08-20
SV2003000741A (es) 2003-01-13
MY141607A (en) 2010-05-31
CA2425497C (en) 2010-08-17
ATE362919T1 (de) 2007-06-15
HRP20030385A2 (en) 2003-08-31
SK5432003A3 (en) 2004-09-08
WO2002040451A2 (en) 2002-05-23
CA2425497A1 (en) 2002-05-23
DK1353910T3 (da) 2007-09-10
AU2432102A (en) 2002-05-27
DE60128587T2 (de) 2008-01-31
KR20030045194A (ko) 2003-06-09
ECSP034598A (es) 2003-06-25
EA200300579A1 (ru) 2003-12-25
BR0115424A (pt) 2003-10-21
PL211018B1 (pl) 2012-03-30
EP1353910B1 (en) 2007-05-23
UA77165C2 (en) 2006-11-15
PE20020798A1 (es) 2002-09-06
PL360991A1 (en) 2004-09-20
NO20032215D0 (no) 2003-05-15
DZ3454A1 (fr) 2002-05-23
SK287794B6 (sk) 2011-10-04
EP1353910A2 (en) 2003-10-22
EA006919B1 (ru) 2006-04-28
AU2002224321B2 (en) 2006-10-19
DE60128587D1 (de) 2007-07-05
CY1106682T1 (el) 2012-05-23
TWI235151B (en) 2005-07-01
JP2004521084A (ja) 2004-07-15
HUP0301862A2 (hu) 2003-09-29

Similar Documents

Publication Publication Date Title
HUP0301842A3 (en) Lactam compound, pharmaceutical composition containing it and use of it for producing pharmaceutical composition
HUP0302257A3 (en) 4-hydrazino-5-hydroxy-5-pyrazol derivatives, pharmaceutical compositions containing them, process for producing them and their intermediates
HUP0302519A3 (en) Crystalline forms of atorvastatin, process for their preparation and pharmaceutical compositions containing them
HUP0402063A3 (en) Indole-2-carboxamides process for producing them, pharmaceutical compositions containing them and use thereof
HUP0301802A3 (en) Process for producing carvedilol, crystalline carvedilol, process for producing it and pharmaceutical composition containing it
HUP0301459A3 (en) Chemical compounds process for producing them and pharmaceutical compositions containing them
HUP0303128A3 (en) Novel succinate salt of o-desmethyl-venlafaxine, process for preparation thereof, its use and pharmaceutical composition containing it
HUP0301862A3 (en) Lactam compound, pharmaceutical composition containing it, process for producing it, intermediates and use of it for producing pharmaceutical composition
PL343726A1 (en) 1-[(1-substituted-4-piperidinyl)methyl]-4-piperidine derivatives, process for producing the same, medicinal compositions containing the same and intermediates of these compounds
HUP0300826A3 (en) Polymorphs of an epothilone analog, process for their preparation and pharmaceutical compositions containing them
HUP0402264A3 (en) Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines process for preparing them, pharmaceutical compositions containing them and use thereof
HUP0300057A3 (en) Glucopyranosyloxy benzylbenzene derivatives, pharmaceutical compositions containing the same and intermediates for the preparation of the derivatives
HUP0302358A3 (en) Piperazinedione compounds and use of them for producing pharmaceutical compositions
HUP0301463A3 (en) Process for the preparation of substituted octanoyl amides and the intermediates
HUP0103987A3 (en) Phenylpiperazinylalkyl carboxylic acid amid derivatives, process for their preparation, pharmaceutical compositions containing them and their intermediates
HUP0105108A3 (en) Amide compounds, process for their preparation and pharmaceutical compositions containing them
HUP0301811A3 (en) Compounds having hypolipedemic and hypocholesteremic activities, process for their prreparation and pharmaceutical compositions containing them and their use, intermediates
HUP0401747A3 (en) Piridazine derivatives of hydrazono-malonitriles, their use, process for preparation of the compounds and pharmaceutical compositions containing the compounds
HUP0204563A3 (en) Process for preparation of 3,3-diarylpropylamine derivatives and their intermediates and their use for preparation of pharmaceutical compositions
HUP0400350A3 (en) Novel cyano-substituted dihydropyrimidine compounds, process for producing them, their use and pharmaceutical compositions containing them
HUP0100489A3 (en) New piperidine-4-sulphonamide compounds, process for their preparation and pharmaceutical compositions containing them
HUP0302429A3 (en) 4-amino-quinazolines, process for producing them, pharmaceutical compositions containing them and their use
HUP0202322A2 (en) A substantially crystalline form of melagatran, process for obtaining it, pharmaceutical composition containing thereof and its use
HUP0202379A3 (en) New compounds, process for producing them and pharmaceutical compositions containing them
HUP0105456A2 (en) Aspartate derivative of amlodipine, process for producing it and pharmaceutical composition containing it

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees