HUP0203781A2 - Májszövet-forrás - Google Patents

Májszövet-forrás

Info

Publication number
HUP0203781A2
HUP0203781A2 HU0203781A HUP0203781A HUP0203781A2 HU P0203781 A2 HUP0203781 A2 HU P0203781A2 HU 0203781 A HU0203781 A HU 0203781A HU P0203781 A HUP0203781 A HU P0203781A HU P0203781 A2 HUP0203781 A2 HU P0203781A2
Authority
HU
Hungary
Prior art keywords
liver tissue
tissue source
cells
subject
tissues
Prior art date
Application number
HU0203781A
Other languages
English (en)
Inventor
Edward L. Lecluyse
Lola Reid
Original Assignee
University Of North Carolina At Chapel Hill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22645867&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0203781(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University Of North Carolina At Chapel Hill filed Critical University Of North Carolina At Chapel Hill
Publication of HUP0203781A2 publication Critical patent/HUP0203781A2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0672—Stem cells; Progenitor cells; Precursor cells; Oval cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgyát eljárások képezik diploid sejtek, köztükprogenitor- vagy őssejtek szívműködés nélküli donor holttestekszöveteiből történő kinyerésére. A találmány tárgyát képezik atalálmány szerinti eljárás alkalmazásával előállított sejtekettartalmazó készítmények is. A találmány szerinti eljárás alkalmasbeültetésre használható sejtek és szövetek előállítására. Ó
HU0203781A 2000-01-19 2001-01-19 Májszövet-forrás HUP0203781A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17679800P 2000-01-19 2000-01-19
PCT/US2001/001821 WO2001053462A1 (en) 2000-01-19 2001-01-19 Liver tissue source

Publications (1)

Publication Number Publication Date
HUP0203781A2 true HUP0203781A2 (hu) 2003-03-28

Family

ID=22645867

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203781A HUP0203781A2 (hu) 2000-01-19 2001-01-19 Májszövet-forrás

Country Status (16)

Country Link
US (2) US20020039786A1 (hu)
EP (1) EP1252293B1 (hu)
JP (1) JP2003520596A (hu)
CN (2) CN101955906A (hu)
AU (1) AU782683B2 (hu)
BR (1) BR0107917A (hu)
CA (1) CA2397927A1 (hu)
DK (1) DK1252293T3 (hu)
ES (1) ES2395821T3 (hu)
HU (1) HUP0203781A2 (hu)
IL (2) IL150819A0 (hu)
MX (1) MXPA02007137A (hu)
PT (1) PT1252293E (hu)
RU (1) RU2002122108A (hu)
WO (1) WO2001053462A1 (hu)
ZA (1) ZA200205887B (hu)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
US7687057B2 (en) 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US7749693B2 (en) * 1998-09-29 2010-07-06 Lifeline Scientific, Inc. Method of determining that an organ is not suitable for transplantation and using it for testing substances
DK2048228T3 (en) * 1999-01-19 2016-05-09 Univ North Carolina Human liver progenitors
MXPA03008882A (es) 2001-03-27 2003-12-08 Vertex Pharma Composiciones y metodos utiles para la infeccion por hcv.
WO2003027253A2 (en) * 2001-09-26 2003-04-03 University Of North Carolina At Chapel Hill Variants of alpha-fetoprotein coding and expression sequences
AU2003242967A1 (en) * 2002-07-12 2004-02-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method and device for inducing biological processes by micro-organs
EP1576117A4 (en) * 2002-07-19 2006-02-01 Vesta Therapeutics Inc METHOD FOR OBTAINING VIABLE HUMAN LIVER CELLS, INCLUDING STEM CELLS / HEPATIC PRECURSORS
US7074561B2 (en) * 2002-10-22 2006-07-11 Biomerieux, Inc. Isothermal amplification based assay for the detection and quantitation of alpha-fetoprotein mRNA
CA2547787A1 (en) * 2003-12-01 2005-06-16 Vertex Pharmaceuticals Incorporated Compositions comprising fetal liver cells and methods useful for hcv infection
ATE548447T1 (de) * 2004-01-14 2012-03-15 Novahep Ab Menschlicher hepatische vorläuferzellen und verfahren zur verwendung davon
AU2005306676B2 (en) * 2004-11-17 2010-02-11 The Rogosin Institute Scoring method for determining pancreas suitability for islet isolation
US7604929B2 (en) 2005-04-21 2009-10-20 In Vitro Technologies, Inc. Cellular compositions and methods for their preparation
PL2281875T3 (pl) 2005-12-21 2018-08-31 Université Catholique de Louvain Wyizolowane komórki macierzyste wątroby
US8273253B2 (en) 2007-03-02 2012-09-25 Smith & Nephew Plc Apparatus and method for filter cleaning by ultrasound, backwashing and filter movement during the filtration of biological samples
EP2179034A1 (en) 2007-07-20 2010-04-28 Cellartis AB A novel population of hepatocytes derived via definitive endoderm (de-hep) from human blastocysts stem cells
EP2268286B1 (en) * 2008-04-09 2016-04-06 The University of North Carolina At Chapel Hill Methods of regulating actin cytoskeletal rearrangement and intercellular gap formation
JP5629683B2 (ja) 2008-07-25 2014-11-26 スミス アンド ネフュー ピーエルシーＳｍｉｔｈ ＆ Ｎｅｐｈｅｗ Ｐｕｂｌｉｃ Ｌｉｍｉｔｅｄ Ｃｏｍｐａｎｙ 分離装置用コントローラ
US20130323708A1 (en) * 2009-07-01 2013-12-05 Massachusetts Institute Of Technology Isolated adult cells, artificial organs, rehabilitated organs, research tools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same
EP2392648A1 (en) 2010-06-04 2011-12-07 Institut Pasteur Methods for obtaining stem cells
JPWO2013115322A1 (ja) * 2012-02-02 2015-05-11 タカラバイオ株式会社 細胞の保存方法
US9772325B2 (en) 2013-06-14 2017-09-26 Biotranex, Llc Method for measuring bile salt export transport and/or formation activity
DK3016665T3 (da) 2013-07-05 2019-11-25 Univ Catholique Louvain Konditioneret medium fra humane voksne leverstamceller og dets anvendelse i behandlingen af leverlidelser
WO2016001839A1 (en) * 2014-06-30 2016-01-07 Stempeutics Research Pvt. Ltd. Management of liver disease using pooled mesenchymal stromal cells
US11697799B2 (en) 2019-04-15 2023-07-11 Ossium Health, Inc. System and method for extraction and cryopreservation of bone marrow
US20220330530A1 (en) * 2019-09-13 2022-10-20 The University Of North Carolina At Chapel Hill Method of making human mouse xenografts
EP4181675A4 (en) 2020-07-18 2024-04-24 Ossium Health Inc PERMEATION OF WHOLE VERTEBRAL BODY WITH CRYOPROTECTIVE USING VACUUM-ASSISTED DIFFUSION
EP4228406A1 (en) 2020-10-14 2023-08-23 Ossium Health, Inc. Systems and methods for extraction and cryopreservation of bone marrow
EP4262831A1 (en) 2020-12-18 2023-10-25 Ossium Health, Inc. Methods of cell therapies
CN113804609B (zh) * 2021-09-13 2024-03-29 复旦大学附属中山医院 一种检测异位胸腺组织的方法及应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6069005A (en) * 1991-08-07 2000-05-30 Albert Einstein College Of Medicine Of Yeshwa University Hapatoblasts and method of isolating same
EP0597964A4 (en) * 1991-08-07 1994-11-30 Einstein Coll Med PROLIFERATION OF HEPATOCYTE PRECURSORS.
US5405742A (en) * 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
DE69434637T2 (de) 1993-11-19 2006-09-21 Albert Einstein College Of Medicine Of Yeshivauniversity, A Division Of Yeshiva Hepatoblasten und verfahren zu ihrer isolierung
CA2146735C (en) * 1994-04-11 2007-02-20 Chise Tateno Liver parenchymal cells having clonal growth ability, method for obtaining same, method for subculturing same, and subculturing system of primary hepatocytes
US5843024A (en) * 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US6908763B1 (en) * 1997-08-22 2005-06-21 The Board Of Trustees Of The Leland Stanford Junior University Mammalian common lymphoid progenitor cell
US6129911A (en) * 1998-07-10 2000-10-10 Rhode Island Hospital, A Lifespan Partner Liver stem cell
DK2048228T3 (en) 1999-01-19 2016-05-09 Univ North Carolina Human liver progenitors

Also Published As

Publication number Publication date
EP1252293A1 (en) 2002-10-30
RU2002122108A (ru) 2004-03-27
EP1252293B1 (en) 2012-10-03
AU3099101A (en) 2001-07-31
AU782683B2 (en) 2005-08-18
WO2001053462A1 (en) 2001-07-26
CN101955906A (zh) 2011-01-26
US20100233808A1 (en) 2010-09-16
ES2395821T3 (es) 2013-02-15
IL150819A (en) 2009-06-15
IL150819A0 (en) 2003-02-12
MXPA02007137A (es) 2004-09-06
CA2397927A1 (en) 2001-07-26
DK1252293T3 (da) 2013-01-14
BR0107917A (pt) 2003-02-11
ZA200205887B (en) 2003-07-23
JP2003520596A (ja) 2003-07-08
US20020039786A1 (en) 2002-04-04
CN1411504A (zh) 2003-04-16
PT1252293E (pt) 2013-01-23

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