HUP0201068A3 - Pharmaceutical compositions of erythropoietin - Google Patents
Pharmaceutical compositions of erythropoietinInfo
- Publication number
- HUP0201068A3 HUP0201068A3 HU0201068A HUP0201068A HUP0201068A3 HU P0201068 A3 HUP0201068 A3 HU P0201068A3 HU 0201068 A HU0201068 A HU 0201068A HU P0201068 A HUP0201068 A HU P0201068A HU P0201068 A3 HUP0201068 A3 HU P0201068A3
- Authority
- HU
- Hungary
- Prior art keywords
- erythropoietin
- pharmaceutical compositions
- pharmaceutical
- compositions
- Prior art date
Links
- 102000003951 Erythropoietin Human genes 0.000 title 1
- 108090000394 Erythropoietin Proteins 0.000 title 1
- 229940105423 erythropoietin Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical group [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12859699P | 1999-04-09 | 1999-04-09 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0201068A2 HUP0201068A2 (en) | 2002-08-28 |
| HUP0201068A3 true HUP0201068A3 (en) | 2002-10-28 |
Family
ID=22436082
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0201068A HUP0201068A3 (en) | 1999-04-09 | 2000-04-07 | Pharmaceutical compositions of erythropoietin |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US6696056B1 (hu) |
| EP (1) | EP1181036B1 (hu) |
| JP (1) | JP2002541208A (hu) |
| KR (1) | KR100740794B1 (hu) |
| CN (1) | CN1165339C (hu) |
| AR (1) | AR029623A1 (hu) |
| AT (1) | ATE401908T1 (hu) |
| AU (1) | AU775041B2 (hu) |
| BG (1) | BG106046A (hu) |
| BR (1) | BR0010665A (hu) |
| CA (1) | CA2369444C (hu) |
| CY (1) | CY1108418T1 (hu) |
| DE (1) | DE60039598D1 (hu) |
| DK (1) | DK1181036T3 (hu) |
| ES (1) | ES2308978T3 (hu) |
| HK (1) | HK1041445B (hu) |
| HU (1) | HUP0201068A3 (hu) |
| IL (1) | IL145816A0 (hu) |
| MX (1) | MXPA01010208A (hu) |
| NO (1) | NO20014893L (hu) |
| NZ (1) | NZ515380A (hu) |
| PL (1) | PL203797B1 (hu) |
| PT (1) | PT1181036E (hu) |
| RU (1) | RU2225221C2 (hu) |
| TR (1) | TR200103788T2 (hu) |
| WO (1) | WO2000061169A1 (hu) |
| ZA (1) | ZA200109236B (hu) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7304150B1 (en) | 1998-10-23 | 2007-12-04 | Amgen Inc. | Methods and compositions for the prevention and treatment of anemia |
| PL203797B1 (pl) * | 1999-04-09 | 2009-11-30 | Ortho Mcneil Pharm Inc | Kompozycje farmaceutyczne erytropoetyny |
| US7371787B2 (en) * | 2000-04-14 | 2008-05-13 | Viance, Llc | Methods of incorporating treatment agents into wood based composite products |
| NZ522030A (en) * | 2000-05-15 | 2004-11-26 | F | Erythropoietin composition with a multiple charged inorganic anion i.e. a sulfate a citrate or a phosphate to stabilize the composition |
| US6818613B2 (en) * | 2001-11-07 | 2004-11-16 | Ortho-Mcneil Pharmaceutical, Inc. | Aqueous sustained-release formulations of proteins |
| EA009676B1 (ru) * | 2003-06-10 | 2008-02-28 | Эл Джи Лайф Сайенсиз Лтд. | Водный препарат эритропоэтина человека |
| DE10333317A1 (de) * | 2003-07-22 | 2005-02-17 | Biotecon Therapeutics Gmbh | Formulierung für Proteinarzneimittel ohne Zusatz von humanem Serumalbumin (HSA) |
| JP2007506678A (ja) * | 2003-09-23 | 2007-03-22 | アルコン，インコーポレイテッド | 注入のためのトリアムシノロンアセトアニドおよび酢酸アネコルタブの処方物 |
| US7141544B2 (en) * | 2003-10-10 | 2006-11-28 | Baxter International, Inc. | Stabilization of pharmaceutical protein formulations with small peptides |
| DE102004011663B4 (de) * | 2004-03-10 | 2006-04-27 | Bioceuticals Arzneimittel Ag | Erythropoietin-Flüssigformulierung |
| US7588745B2 (en) * | 2004-04-13 | 2009-09-15 | Si Options, Llc | Silicon-containing products |
| US20050255112A1 (en) * | 2004-05-17 | 2005-11-17 | Lee Jong Y | Compositions and methods for preventing erythropoietin-associated hypertension |
| US7597884B2 (en) * | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| KR20070085227A (ko) * | 2004-08-09 | 2007-08-27 | 앨리오스 바이오파마 인크. | 합성 초글리코실화, 프로테아제 저항성 폴리펩티드 변이체,경구 제제 및 이를 이용한 방법 |
| WO2006138181A2 (en) | 2005-06-14 | 2006-12-28 | Amgen Inc. | Self-buffering protein formulations |
| US7790679B2 (en) * | 2005-08-05 | 2010-09-07 | Amgen Inc. | Pharmaceutical formulations |
| CN101015684B (zh) * | 2006-02-10 | 2011-08-24 | 华北制药集团新药研究开发有限责任公司 | 一种重组人红细胞生成素溶液制剂 |
| US20080050749A1 (en) * | 2006-08-17 | 2008-02-28 | Ildiko Amann-Zalan | Use of bnp-type peptides for the stratification of therapy with erythropoietic stimulating agents |
| US8796206B2 (en) * | 2007-11-15 | 2014-08-05 | Amgen Inc. | Aqueous formulation of erythropoiesis stimulating protein stabilised by antioxidants for parenteral administration |
| US8883146B2 (en) | 2007-11-30 | 2014-11-11 | Abbvie Inc. | Protein formulations and methods of making same |
| KR100956431B1 (ko) | 2007-12-07 | 2010-05-06 | 주식회사 제이에스마루 | 혈장크린접착제 및 이의 제조방법 |
| PT2342223T (pt) | 2008-09-26 | 2017-07-07 | Lilly Co Eli | Polipéptidos de eritropoetina animal modificados e suas utilizações |
| JP6463268B2 (ja) | 2012-09-07 | 2019-01-30 | コヒラス・バイオサイエンシズ・インコーポレイテッド | 安定水性アダリムマブ製剤 |
| US11229702B1 (en) | 2015-10-28 | 2022-01-25 | Coherus Biosciences, Inc. | High concentration formulations of adalimumab |
| US11071782B2 (en) | 2016-04-20 | 2021-07-27 | Coherus Biosciences, Inc. | Method of filling a container with no headspace |
| WO2018075818A1 (en) | 2016-10-21 | 2018-04-26 | Amgen Inc. | Pharmaceutical formulations and methods of making the same |
| AU2018281334A1 (en) * | 2017-06-06 | 2019-12-19 | Kindred Biosciences, Inc. | Erythropoietin and analogs for veterinary use |
| CN111150837B (zh) * | 2020-02-11 | 2022-07-12 | 中国人民解放军陆军军医大学 | Epo在抗金黄色葡萄球菌感染药物中的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6191131A (ja) * | 1984-10-09 | 1986-05-09 | Chugai Pharmaceut Co Ltd | 医薬品の吸着防止方法および組成物 |
| JPS6197229A (ja) * | 1984-10-18 | 1986-05-15 | Chugai Pharmaceut Co Ltd | 安定なエリトロポエチン製剤 |
| DK173067B1 (da) * | 1986-06-27 | 1999-12-13 | Univ Washington | Humant erythropoietin-gen, fremgangsmåde til ekspression deraf i transficerede cellelinier, de transficerede cellelinier sa |
| DE3729863A1 (de) * | 1987-09-05 | 1989-03-16 | Boehringer Mannheim Gmbh | Stabilisierte erythropoietin-lyophilisate |
| GB8822857D0 (en) | 1988-09-29 | 1988-11-02 | Patralan Ltd | Pharmaceutical formulations |
| GB9001987D0 (en) * | 1990-01-29 | 1990-03-28 | Janssen Pharmaceutica Nv | Improved cyclodextrin based erythropietin formulation |
| US5543575A (en) * | 1990-06-20 | 1996-08-06 | Pioneer-Hi-Bred International, Inc. | Inbred corn line PHK46 |
| DE4126984A1 (de) * | 1991-08-15 | 1993-02-18 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von humanprotein-enthaltenden, gut vertraeglichen arzneimitteln fuer infusions- oder injektionszwecke |
| DE4126983A1 (de) * | 1991-08-15 | 1993-02-18 | Boehringer Mannheim Gmbh | Verfahren zur herstellung von humanprotein-enthaltenden, konservierten arzneimitteln fuer infusions- oder injektionszwecke |
| US5661125A (en) | 1992-08-06 | 1997-08-26 | Amgen, Inc. | Stable and preserved erythropoietin compositions |
| US5766582A (en) | 1994-10-11 | 1998-06-16 | Schering Corporation | Stable, aqueous alfa interferon solution formulations |
| DE19539574A1 (de) * | 1995-10-25 | 1997-04-30 | Boehringer Mannheim Gmbh | Zubereitungen und Verfahren zur Stabilisierung biologischer Materialien mittels Trocknungsverfahren ohne Einfrieren |
| TWI240627B (en) * | 1996-04-26 | 2005-10-01 | Chugai Pharmaceutical Co Ltd | Erythropoietin solution preparation |
| TW586933B (en) | 1996-06-20 | 2004-05-11 | Chugai Pharmaceutical Co Ltd | Compositions for treating liver-complaints using EPO |
| PL203797B1 (pl) * | 1999-04-09 | 2009-11-30 | Ortho Mcneil Pharm Inc | Kompozycje farmaceutyczne erytropoetyny |
-
2000
- 2000-04-07 PL PL351837A patent/PL203797B1/pl unknown
- 2000-04-07 CN CNB008085048A patent/CN1165339C/zh not_active Expired - Fee Related
- 2000-04-07 US US09/545,479 patent/US6696056B1/en not_active Expired - Lifetime
- 2000-04-07 ES ES00921929T patent/ES2308978T3/es not_active Expired - Lifetime
- 2000-04-07 IL IL14581600A patent/IL145816A0/xx unknown
- 2000-04-07 MX MXPA01010208A patent/MXPA01010208A/es active IP Right Grant
- 2000-04-07 AT AT00921929T patent/ATE401908T1/de active
- 2000-04-07 RU RU2001130142/15A patent/RU2225221C2/ru not_active IP Right Cessation
- 2000-04-07 KR KR1020017012906A patent/KR100740794B1/ko not_active IP Right Cessation
- 2000-04-07 PT PT00921929T patent/PT1181036E/pt unknown
- 2000-04-07 EP EP00921929A patent/EP1181036B1/en not_active Expired - Lifetime
- 2000-04-07 CA CA002369444A patent/CA2369444C/en not_active Expired - Fee Related
- 2000-04-07 AU AU42186/00A patent/AU775041B2/en not_active Ceased
- 2000-04-07 BR BR0010665-8A patent/BR0010665A/pt not_active Application Discontinuation
- 2000-04-07 WO PCT/US2000/009414 patent/WO2000061169A1/en active Application Filing
- 2000-04-07 DK DK00921929T patent/DK1181036T3/da active
- 2000-04-07 JP JP2000610501A patent/JP2002541208A/ja active Pending
- 2000-04-07 TR TR2001/03788T patent/TR200103788T2/xx unknown
- 2000-04-07 HU HU0201068A patent/HUP0201068A3/hu unknown
- 2000-04-07 DE DE60039598T patent/DE60039598D1/de not_active Expired - Lifetime
- 2000-04-07 NZ NZ515380A patent/NZ515380A/en not_active IP Right Cessation
- 2000-04-10 AR ARP000101631A patent/AR029623A1/es unknown
-
2001
- 2001-10-08 NO NO20014893A patent/NO20014893L/no not_active Application Discontinuation
- 2001-10-24 BG BG106046A patent/BG106046A/xx unknown
- 2001-11-08 ZA ZA200109236A patent/ZA200109236B/xx unknown
-
2002
- 2002-04-19 HK HK02102987.9A patent/HK1041445B/zh not_active IP Right Cessation
-
2004
- 2004-02-10 US US10/775,928 patent/US20040248797A1/en not_active Abandoned
-
2008
- 2008-10-16 CY CY20081101147T patent/CY1108418T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1041445A1 (en) | Pharmaceutical compositions of erythropoietin | |
| HUP0202513A3 (en) | Betha-carboline pharmaceutical compositions | |
| GB0028088D0 (en) | Pharmaceutical compositions | |
| GB0001662D0 (en) | Pharmaceutical compositions | |
| PL351387A1 (en) | Pharmaceutical composition | |
| IL148864A (en) | Pharmaceutical compositions containing nimesulide | |
| HUP0203311A3 (en) | New pharmaceutical compositions of prolonged effect | |
| AU3556400A (en) | Pharmaceutical compositions | |
| GB9809213D0 (en) | Pharmaceutical compositions | |
| GB9904163D0 (en) | Pharmaceutical compositions | |
| AU4304400A (en) | Novel pharmaceutical compositions comprising 2-isoxazole-8-aminotetralin derivatives | |
| AU6460400A (en) | Pharmaceutical compositions | |
| GB9911017D0 (en) | Pharmaceutical compositions | |
| AU6460200A (en) | Pharmaceutical compositions | |
| AP2000001878A0 (en) | Pharmaceutical compositions | |
| GB9904911D0 (en) | Pharmaceutical compositions | |
| AU6460100A (en) | Pharmaceutical compositions | |
| AU6460300A (en) | Pharmaceutical compositions | |
| IL149470A0 (en) | Pharmaceutical compositions containing carboxamidoadenosine derivatives | |
| IL130325A0 (en) | Pharmaceutical compositions comprising allicin | |
| GB9902651D0 (en) | Pharmaceutical compositions | |
| GB9806487D0 (en) | Pharmaceutical compositions | |
| GB9920652D0 (en) | Pharmaceutical compositions | |
| GB9902591D0 (en) | Pharmaceutical compositions | |
| GB9902594D0 (en) | Pharmaceutical compositions |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |