HUP0200187A2 - Eljárás 1,4,7,10-tetraazaciklododekán előállítására - Google Patents

Eljárás 1,4,7,10-tetraazaciklododekán előállítására

Info

Publication number
HUP0200187A2
HUP0200187A2 HU0200187A HUP0200187A HUP0200187A2 HU P0200187 A2 HUP0200187 A2 HU P0200187A2 HU 0200187 A HU0200187 A HU 0200187A HU P0200187 A HUP0200187 A HU P0200187A HU P0200187 A2 HUP0200187 A2 HU P0200187A2
Authority
HU
Hungary
Prior art keywords
formula
compound
tetraazacyclododecane
preparation
salt
Prior art date
Application number
HU0200187A
Other languages
English (en)
Inventor
Maria Argese
Giuseppe Manfredi
Fabrizio Rebasti
Giorgio Ripa
Original Assignee
Bracco International B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco International B.V. filed Critical Bracco International B.V.
Publication of HUP0200187A2 publication Critical patent/HUP0200187A2/hu
Publication of HUP0200187A3 publication Critical patent/HUP0200187A3/hu
Publication of HU229217B1 publication Critical patent/HU229217B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A találmány szerint az (I) képletű 1,4,7,10-tetraazaciklododekánt az1. reakcióvázlat szerint állítják elő. Ennek során trietiléntetramintglioxálhidráttal kondenzálunk, a kapott (IV) képletű vegyületet 1,2-diklóretánnal reagáltatják dimetilacetamidban nátriumkarbonát éskatalizátorként nátriumbromid jelenlétében, majd a kapott (III)képletű vegyületet só formájában izolálják, dietiléntriaminnalreagáltatva vízben hidrolizálják, és a tetrahidrokloridsó formájábankapott (II) képletű vegyületből az (I) képletű vegyületet kívántesetben felszabadítják. Ó
HU0200187A 1999-03-09 2000-03-06 A process for the preparation of 1,4,7,10-tetraazacyclododecane HU229217B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI000474A IT1309601B1 (it) 1999-03-09 1999-03-09 Processo per la preparazione di 1,4,7,10 tetraazaciclododecano.
PCT/EP2000/001867 WO2000053588A1 (en) 1999-03-09 2000-03-06 A process for the preparation of 1,4,7,10-tetraazacyclododecane

Publications (3)

Publication Number Publication Date
HUP0200187A2 true HUP0200187A2 (hu) 2002-05-29
HUP0200187A3 HUP0200187A3 (en) 2003-08-28
HU229217B1 HU229217B1 (en) 2013-09-30

Family

ID=11382202

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0200187A HU229217B1 (en) 1999-03-09 2000-03-06 A process for the preparation of 1,4,7,10-tetraazacyclododecane

Country Status (18)

Country Link
US (1) US6653470B1 (hu)
EP (1) EP1159272B1 (hu)
JP (1) JP4564667B2 (hu)
KR (1) KR100614535B1 (hu)
CN (1) CN1155584C (hu)
AT (1) ATE277914T1 (hu)
AU (1) AU772706B2 (hu)
CA (1) CA2366600C (hu)
DE (1) DE60014330T2 (hu)
EA (1) EA003706B1 (hu)
ES (1) ES2228474T3 (hu)
HK (1) HK1044770B (hu)
HU (1) HU229217B1 (hu)
IL (2) IL145298A0 (hu)
IS (1) IS2430B (hu)
IT (1) IT1309601B1 (hu)
WO (1) WO2000053588A1 (hu)
ZA (1) ZA200107380B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2830253B1 (fr) * 2001-09-28 2005-02-04 Air Liquide Nouveau procede de preparation de macrocycles azotes c-fonctionnalises et nouveaux intermediaires obtenus
US11473032B2 (en) 2010-02-02 2022-10-18 Fuchs Petrolub Se Constant velocity joint having a boot
CN103360333B (zh) * 2013-07-22 2016-03-30 厦门市华兴化工有限公司 一种高纯度轮环藤宁的制备方法
CN104387336B (zh) * 2014-10-24 2016-04-27 上海应用技术学院 1,4,7,10-四氮杂环十二烷及其纳滤膜的制备方法
EP4067348A1 (en) 2021-03-30 2022-10-05 Bracco Imaging SPA Process for the preparation of cyclen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9504922D0 (en) * 1995-03-10 1995-04-26 Nycomed As Process
IT1284046B1 (it) * 1996-06-21 1998-05-08 Bracco Spa Processo per la preparazione di tetraazamacrocicli
IT1291673B1 (it) * 1997-04-28 1999-01-19 Bracco Spa Processo per la preparazione di 1,4,7,10 - tetraazaciclododecano

Also Published As

Publication number Publication date
IT1309601B1 (it) 2002-01-24
US6653470B1 (en) 2003-11-25
HUP0200187A3 (en) 2003-08-28
ZA200107380B (en) 2002-09-18
EA003706B1 (ru) 2003-08-28
ATE277914T1 (de) 2004-10-15
CA2366600C (en) 2009-09-15
AU772706B2 (en) 2004-05-06
JP2002539117A (ja) 2002-11-19
IL145298A0 (en) 2002-06-30
IL145298A (en) 2006-04-10
IS2430B (is) 2008-10-15
ES2228474T3 (es) 2005-04-16
HK1044770A1 (en) 2002-11-01
HU229217B1 (en) 2013-09-30
DE60014330D1 (de) 2004-11-04
EP1159272A1 (en) 2001-12-05
ITMI990474A1 (it) 2000-09-09
WO2000053588A1 (en) 2000-09-14
CA2366600A1 (en) 2000-09-14
EA200100864A1 (ru) 2002-02-28
KR20020004957A (ko) 2002-01-16
CN1343203A (zh) 2002-04-03
IS6058A (is) 2001-08-21
CN1155584C (zh) 2004-06-30
DE60014330T2 (de) 2005-11-17
KR100614535B1 (ko) 2006-08-23
EP1159272B1 (en) 2004-09-29
AU3286000A (en) 2000-09-28
HK1044770B (zh) 2005-04-01
JP4564667B2 (ja) 2010-10-20

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