HUP0105301A2 - Riluzol és alfa-tokoferol kombinációját tartalmazó gyógyszerkészítmény és alkalmazása - Google Patents
Riluzol és alfa-tokoferol kombinációját tartalmazó gyógyszerkészítmény és alkalmazásaInfo
- Publication number
- HUP0105301A2 HUP0105301A2 HU0105301A HUP0105301A HUP0105301A2 HU P0105301 A2 HUP0105301 A2 HU P0105301A2 HU 0105301 A HU0105301 A HU 0105301A HU P0105301 A HUP0105301 A HU P0105301A HU P0105301 A2 HUP0105301 A2 HU P0105301A2
- Authority
- HU
- Hungary
- Prior art keywords
- alpha
- pharmaceutical composition
- composition containing
- combination
- riluzole
- Prior art date
Links
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 title abstract 4
- FTALBRSUTCGOEG-UHFFFAOYSA-N Riluzole Chemical compound C1=C(OC(F)(F)F)C=C2SC(N)=NC2=C1 FTALBRSUTCGOEG-UHFFFAOYSA-N 0.000 title abstract 3
- 229940087168 alpha tocopherol Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229960004181 riluzole Drugs 0.000 title abstract 2
- 229960000984 tocofersolan Drugs 0.000 title abstract 2
- 239000002076 α-tocopherol Substances 0.000 title abstract 2
- 235000004835 α-tocopherol Nutrition 0.000 title abstract 2
- 239000002671 adjuvant Substances 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Fats And Perfumes (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- External Artificial Organs (AREA)
- Anti-Oxidant Or Stabilizer Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Abstract
A találmány tárgyát a-tokoferol és riluzol vagy ez utóbbi egygyógyszerészetileg elfogadható sójának, 10 és 400 tömegrész közöttimennyiségű riluzolból, és 250 és 4000 tömegrész közötti mennyiségű a-tokoferolból álló, adott esetben kompatibilis és gyógyszerészetilegelfogadható hígítószert vagy adjuvánst is tartalmazó kombinációjáttartalmazó gyógyszerkészítmény, és annak az izomsorvadásos szklerózislaterális kezelésére való alkalmazása képezi. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9814250A FR2785808B1 (fr) | 1998-11-13 | 1998-11-13 | Association riluzole et alpha-tocopherol |
PCT/FR1999/002753 WO2000028992A1 (fr) | 1998-11-13 | 1999-11-09 | Association riluzole et alpha-tocopherol |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0105301A2 true HUP0105301A2 (hu) | 2002-05-29 |
HUP0105301A3 HUP0105301A3 (en) | 2006-07-28 |
HU226067B1 HU226067B1 (en) | 2008-04-28 |
Family
ID=9532674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0105301A HU226067B1 (en) | 1998-11-13 | 1999-11-09 | Pharmaceutical composition containing riluzole and alpha-tocopherol combination and its use |
Country Status (23)
Country | Link |
---|---|
US (2) | US6642262B2 (hu) |
EP (1) | EP1128829B1 (hu) |
JP (1) | JP4693241B2 (hu) |
KR (1) | KR100641472B1 (hu) |
CN (1) | CN1177587C (hu) |
AT (1) | ATE295168T1 (hu) |
AU (1) | AU776242B2 (hu) |
BR (1) | BR9915292A (hu) |
CA (1) | CA2350671C (hu) |
CZ (1) | CZ298808B6 (hu) |
DE (1) | DE69925301T2 (hu) |
DK (1) | DK1128829T3 (hu) |
EA (1) | EA003671B1 (hu) |
ES (1) | ES2239858T3 (hu) |
FR (1) | FR2785808B1 (hu) |
HK (1) | HK1041220B (hu) |
HU (1) | HU226067B1 (hu) |
IL (1) | IL142708A0 (hu) |
NO (1) | NO328349B1 (hu) |
PT (1) | PT1128829E (hu) |
TR (1) | TR200101346T2 (hu) |
WO (1) | WO2000028992A1 (hu) |
ZA (1) | ZA200103810B (hu) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2786101B1 (fr) * | 1998-11-24 | 2002-07-05 | Aventis Laboratoire | Utilisation de la nicergoline dans le traitement de la spasticite |
US20090149518A1 (en) * | 2005-10-18 | 2009-06-11 | Ono Pharmaceutical Co., Ltd. | Pharmaceutical for protection of motor nerve in patient with amyotrophic lateral sclerosis |
US20070099156A1 (en) * | 2005-10-28 | 2007-05-03 | Jeff Wagner | Self-etching dental primer compositions and methods and systems utilizing such compositions |
FR2957077B1 (fr) * | 2010-03-02 | 2012-04-13 | Univ Dauvergne Clermont I | Utilisation du riluzole pour traiter ou prevenir les effets indesirables d'agents anti-cancereux |
WO2014145776A2 (en) * | 2013-03-15 | 2014-09-18 | Baylor College Of Medicine | Msp and its receptors in the therapy of amyotrophic lateral sclerosis |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2688138B1 (fr) * | 1992-03-06 | 1995-05-05 | Rhone Poulenc Rorer Sa | Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique. |
US5843641A (en) * | 1993-02-26 | 1998-12-01 | Massachusetts Institute Of Technology | Methods for the daignosis, of familial amyotrophic lateral sclerosis |
US6380252B1 (en) * | 1996-07-05 | 2002-04-30 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine for increasing the levels of IGF-1 |
US5780489A (en) * | 1996-08-21 | 1998-07-14 | Brooks; Benjamin Rix | Method for treating amyotrophic lateral sclerosis |
JP3889844B2 (ja) * | 1997-02-10 | 2007-03-07 | 龍兒 梶 | 筋萎縮性側索硬化症治療剤 |
FR2782008B1 (fr) * | 1998-08-07 | 2003-04-25 | Sod Conseils Rech Applic | Utilisation d'extraits de ginkgo biloba pour preparer un medicament destine a traiter la sclerose laterale amyotrophique |
-
1998
- 1998-11-13 FR FR9814250A patent/FR2785808B1/fr not_active Expired - Fee Related
-
1999
- 1999-11-09 AT AT99972101T patent/ATE295168T1/de active
- 1999-11-09 ES ES99972101T patent/ES2239858T3/es not_active Expired - Lifetime
- 1999-11-09 AU AU11655/00A patent/AU776242B2/en not_active Ceased
- 1999-11-09 HU HU0105301A patent/HU226067B1/hu not_active IP Right Cessation
- 1999-11-09 DK DK99972101T patent/DK1128829T3/da active
- 1999-11-09 TR TR2001/01346T patent/TR200101346T2/xx unknown
- 1999-11-09 WO PCT/FR1999/002753 patent/WO2000028992A1/fr active IP Right Grant
- 1999-11-09 PT PT99972101T patent/PT1128829E/pt unknown
- 1999-11-09 DE DE69925301T patent/DE69925301T2/de not_active Expired - Lifetime
- 1999-11-09 KR KR1020017005912A patent/KR100641472B1/ko not_active IP Right Cessation
- 1999-11-09 CZ CZ20011561A patent/CZ298808B6/cs not_active IP Right Cessation
- 1999-11-09 BR BR9915292-4A patent/BR9915292A/pt not_active Application Discontinuation
- 1999-11-09 JP JP2000582039A patent/JP4693241B2/ja not_active Expired - Fee Related
- 1999-11-09 CA CA2350671A patent/CA2350671C/fr not_active Expired - Fee Related
- 1999-11-09 EP EP99972101A patent/EP1128829B1/fr not_active Expired - Lifetime
- 1999-11-09 EA EA200100530A patent/EA003671B1/ru not_active IP Right Cessation
- 1999-11-09 CN CNB998131903A patent/CN1177587C/zh not_active Expired - Fee Related
- 1999-11-09 IL IL14270899A patent/IL142708A0/xx not_active IP Right Cessation
-
2001
- 2001-05-10 NO NO20012308A patent/NO328349B1/no not_active IP Right Cessation
- 2001-05-10 ZA ZA200103810A patent/ZA200103810B/en unknown
- 2001-05-11 US US09/854,318 patent/US6642262B2/en not_active Expired - Lifetime
-
2002
- 2002-04-22 HK HK02102998.6A patent/HK1041220B/zh not_active IP Right Cessation
-
2003
- 2003-02-18 US US10/369,151 patent/US20030125363A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU6613896A (en) | Chemical compounds | |
AU6865298A (en) | The use of cryoprotective agent compounds during cryosurgery | |
AU688952B2 (en) | Thrombin inhibitors | |
AU3951699A (en) | The use of an anti-microbial compound for disinfection | |
MX9704377A (es) | Uso de pramipexole como agente neuroprotector. | |
UA34466C2 (uk) | Засіб для несистемної боротьби з паразитуючими комахами | |
ES2114487B1 (es) | Mezcla estabilizante sinergistica. | |
NO307336B1 (no) | 2-[(Dihydro)pyrazolyl-3'-oksylmetylen]anilider, anvendelse derav, samt middel inneholdende forbindelsen og mellomprodukter for fremstilling av forbindelsen | |
AU4292096A (en) | Use of guanylate cyclase inhibitors for reducing intraocular pressure | |
DE60112974D1 (en) | Carbolinderivate | |
MX9205432A (es) | Compuestos inhibidores de la biosintesis de leucotrienos y composicion farmaceutica que los contiene. | |
YU41199A (sh) | Hinoksalindioni | |
DE60216233D1 (en) | Carbolinderivate | |
AU2002213421A1 (en) | Condensed pyridoindole derivatives | |
CA2154572A1 (fr) | Application du riluzole dans le traitement du neuro-sida | |
MXPA02012076A (es) | Compuestos quimicos. | |
MXPA02012659A (es) | Derivados de pirazindiona condensados. | |
GB9514518D0 (en) | Guanidine salt inhibitors of NO synthase and cyclooxygenase | |
AU2002213419A1 (en) | Condensed pyridoindole derivatives | |
HUP0105301A2 (hu) | Riluzol és alfa-tokoferol kombinációját tartalmazó gyógyszerkészítmény és alkalmazása | |
FR2718013B1 (fr) | Dispositif d'enclouage centro-médullaire notamment pour fractures sous cervicales du fémur. | |
AU2001296699A1 (en) | Condensed pyrazindione derivatives as pde inhibitors | |
MXPA02012472A (es) | Compuestos quimicos. | |
AU6206698A (en) | Isoflavone derivatives, processes for the preparation thereof and pharmac euticalcompositions containing them | |
AU5622599A (en) | Use of 5-amino-pyrazol-derivatives for combating micro-organisms |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FH91 | Appointment of a representative |
Free format text: FORMER REPRESENTATIVE(S): DR. LANG TIVADARNE, S.B.G. & K. SZABADALMI UEGYVIVOEI IRODA, HU Representative=s name: DANUBIA SZABADALMI ES JOGI IRODA KFT., HU |
|
FH92 | Termination of representative |
Representative=s name: DR. LANG TIVADARNE, S.B.G. & K. SZABADALMI UEG, HU |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |