HUP0104993A2 - Eljárás és eszköz hatóanyagok kontrollált bevitelére - Google Patents

Eljárás és eszköz hatóanyagok kontrollált bevitelére

Info

Publication number
HUP0104993A2
HUP0104993A2 HU0104993A HUP0104993A HUP0104993A2 HU P0104993 A2 HUP0104993 A2 HU P0104993A2 HU 0104993 A HU0104993 A HU 0104993A HU P0104993 A HUP0104993 A HU P0104993A HU P0104993 A2 HUP0104993 A2 HU P0104993A2
Authority
HU
Hungary
Prior art keywords
phase
wall
emptying
cavity
dosage form
Prior art date
Application number
HU0104993A
Other languages
English (en)
Inventor
Padmanabh Bhatt
Evangeline G. Cruz
Noymi Yam
Original Assignee
Alza Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corporation filed Critical Alza Corporation
Publication of HUP0104993A2 publication Critical patent/HUP0104993A2/hu
Publication of HUP0104993A3 publication Critical patent/HUP0104993A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány tárgya hatóanyagot tartalmazó dózisforma (1), valamintkompresszált gyógyszerkészítményt, féligáteresztő falat (2) éstolófázist (5) tartalmazó dózisformából (1) hatóanyag ürülésénekelősegítésére szolgáló eljárás. A találmány szerinti dózisforma (1)tartalmaz üreget (3) meghatározó, legalább egy féligáteresztőtartománnyal és anyagában kialakított vagy kialakíthatókiömlőnyílással (4) rendelkező falat (2); az üregben (3) akiömlőnyílástól (4) távol a fal (2) féligáteresztő tartományávalközlekedőn elrendezett tágulásra képes tolófázist (5); az üregben (3)a kiömlőnyílással (4) szomszédosan, a tágulásra képes tolófázissal (5)közvetlenül vagy közvetve érintkezőn elrendezett hatóanyagfázist (6);továbbá a fal (2) belső felülete és legalább az üregben (3) lévőhatóanyagfázis (6) külső felülete között elrendezett ürülést segítőfázist (7). A találmány szerinti dózisforma ürülést segítő fázissal(7) bevont kompresszált gyógyszerkészítményt tartalmaz. A szóban forgóeljárás lényege, hogy a féligáteresztő fal (2) és a kompresszáltgyógyszerkészítmény között ürülést segítő fázist (7) rendeznek el. Ó
HU0104993A 1998-11-02 1999-10-26 Method and device for controlled delivery of active agents HUP0104993A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10673998P 1998-11-02 1998-11-02

Publications (2)

Publication Number Publication Date
HUP0104993A2 true HUP0104993A2 (hu) 2002-05-29
HUP0104993A3 HUP0104993A3 (en) 2003-02-28

Family

ID=22312996

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0104993A HUP0104993A3 (en) 1998-11-02 1999-10-26 Method and device for controlled delivery of active agents

Country Status (15)

Country Link
US (3) US6368626B1 (hu)
EP (2) EP1126827A2 (hu)
JP (1) JP2002528486A (hu)
KR (1) KR20010075676A (hu)
CN (1) CN1325301A (hu)
AU (1) AU1238500A (hu)
CA (1) CA2350246C (hu)
HK (1) HK1039456A1 (hu)
HU (1) HUP0104993A3 (hu)
IL (1) IL142807A0 (hu)
NO (1) NO20012168L (hu)
NZ (1) NZ511465A (hu)
RU (1) RU2246295C2 (hu)
WO (1) WO2000025753A2 (hu)
ZA (1) ZA200103524B (hu)

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Publication number Priority date Publication date Assignee Title
US7011850B2 (en) 1999-12-16 2006-03-14 Alza Corporation Dosage forms having a barrier layer to laser ablation

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US6855334B2 (en) 2005-02-15
EP1652516A2 (en) 2006-05-03
CA2350246A1 (en) 2000-05-11
US20050136113A1 (en) 2005-06-23
JP2002528486A (ja) 2002-09-03
CA2350246C (en) 2010-04-27
WO2000025753A3 (en) 2000-08-31
KR20010075676A (ko) 2001-08-09
ZA200103524B (en) 2002-05-02
RU2246295C2 (ru) 2005-02-20
NO20012168D0 (no) 2001-05-02
WO2000025753A2 (en) 2000-05-11
EP1652516A3 (en) 2006-05-17
EP1126827A2 (en) 2001-08-29
HUP0104993A3 (en) 2003-02-28
US6368626B1 (en) 2002-04-09
AU1238500A (en) 2000-05-22
IL142807A0 (en) 2002-03-10
NZ511465A (en) 2003-10-31
HK1039456A1 (zh) 2002-04-26
US20020048600A1 (en) 2002-04-25
CN1325301A (zh) 2001-12-05

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