HUP0103665A2 - Izokinolinszármazékok mint urokináz-inhibitorok, eljárás az előállításukra és a vegyületeket tartalmazó gyógyszerkészítmények - Google Patents
Izokinolinszármazékok mint urokináz-inhibitorok, eljárás az előállításukra és a vegyületeket tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP0103665A2 HUP0103665A2 HU0103665A HUP0103665A HUP0103665A2 HU P0103665 A2 HUP0103665 A2 HU P0103665A2 HU 0103665 A HU0103665 A HU 0103665A HU P0103665 A HUP0103665 A HU P0103665A HU P0103665 A2 HUP0103665 A2 HU P0103665A2
- Authority
- HU
- Hungary
- Prior art keywords
- peocess
- isoquinolines
- preparation
- medicaments containing
- urokinase inhibitors
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 150000002537 isoquinolines Chemical class 0.000 title 1
- 239000002797 plasminogen activator inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/48—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
- C07D211/96—Sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9816228.2A GB9816228D0 (en) | 1998-07-24 | 1998-07-24 | Isoquinolines |
| GBGB9908829.6A GB9908829D0 (en) | 1998-07-24 | 1999-04-16 | Isoquinolines |
| PCT/IB1999/001289 WO2000005214A2 (en) | 1998-07-24 | 1999-07-15 | Isoquinolines as urokinase inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0103665A2 true HUP0103665A2 (hu) | 2002-02-28 |
| HUP0103665A3 HUP0103665A3 (en) | 2002-06-28 |
Family
ID=10836172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0103665A HUP0103665A3 (en) | 1998-07-24 | 1999-07-15 | Isoquinolines as urokinase inhibitors, peocess for their preparation and medicaments containing them |
Country Status (39)
| Country | Link |
|---|---|
| EP (1) | EP1077945B1 (hu) |
| JP (1) | JP2002521367A (hu) |
| KR (1) | KR20010083137A (hu) |
| CN (1) | CN1318059A (hu) |
| AR (1) | AR018960A1 (hu) |
| AT (1) | ATE230730T1 (hu) |
| AU (1) | AU745545B2 (hu) |
| BG (1) | BG105252A (hu) |
| BR (1) | BR9912374A (hu) |
| CA (1) | CA2337247A1 (hu) |
| CO (1) | CO5080787A1 (hu) |
| DE (1) | DE69904814T2 (hu) |
| DK (1) | DK1077945T3 (hu) |
| DZ (1) | DZ2852A1 (hu) |
| EA (1) | EA200100073A1 (hu) |
| EE (1) | EE200100049A (hu) |
| ES (1) | ES2189434T3 (hu) |
| GB (2) | GB9816228D0 (hu) |
| GT (1) | GT199900116A (hu) |
| HK (1) | HK1040996A1 (hu) |
| HN (1) | HN1999000116A (hu) |
| HR (1) | HRP20010059A2 (hu) |
| HU (1) | HUP0103665A3 (hu) |
| ID (1) | ID26993A (hu) |
| IS (1) | IS5789A (hu) |
| MA (1) | MA26664A1 (hu) |
| NO (1) | NO20010400L (hu) |
| OA (1) | OA11578A (hu) |
| PA (1) | PA8478901A1 (hu) |
| PE (1) | PE20000937A1 (hu) |
| PL (1) | PL346022A1 (hu) |
| PT (1) | PT1077945E (hu) |
| SI (1) | SI1077945T1 (hu) |
| SK (1) | SK1062001A3 (hu) |
| TN (1) | TNSN99149A1 (hu) |
| TR (1) | TR200100222T2 (hu) |
| TW (1) | TW530049B (hu) |
| UY (1) | UY25663A1 (hu) |
| ZA (1) | ZA200100230B (hu) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003219039A1 (en) * | 2002-03-11 | 2003-09-22 | Curacyte Ag | Urokinase inhibitors, production and use thereof |
| KR20060111524A (ko) | 2003-12-02 | 2006-10-27 | 쉬바르츠파르마에이지 | 펩타이드 화합물들의 중추 신경병증성 통증 치료를 위한신규한 용도 |
| EP1604655A1 (en) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in trigeminal neuralgia |
| EP1604656A1 (en) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating amyotrophic lateral sclerosis (ALS) |
| EA027836B1 (ru) | 2006-06-15 | 2017-09-29 | ЮСиБи ФАРМА ГМБХ | Фармацевтическая комбинация для профилактики, облегчения и/или лечения приступов эпилепсии и ее применение |
-
1998
- 1998-07-24 GB GBGB9816228.2A patent/GB9816228D0/en not_active Ceased
-
1999
- 1999-04-16 GB GBGB9908829.6A patent/GB9908829D0/en not_active Ceased
- 1999-07-15 EE EEP200100049A patent/EE200100049A/xx unknown
- 1999-07-15 DK DK99928177T patent/DK1077945T3/da active
- 1999-07-15 KR KR1020017000956A patent/KR20010083137A/ko not_active Application Discontinuation
- 1999-07-15 PL PL99346022A patent/PL346022A1/xx not_active Application Discontinuation
- 1999-07-15 EA EA200100073A patent/EA200100073A1/ru unknown
- 1999-07-15 PT PT99928177T patent/PT1077945E/pt unknown
- 1999-07-15 AT AT99928177T patent/ATE230730T1/de not_active IP Right Cessation
- 1999-07-15 BR BR9912374-6A patent/BR9912374A/pt not_active IP Right Cessation
- 1999-07-15 OA OA1200100002A patent/OA11578A/en unknown
- 1999-07-15 AU AU45289/99A patent/AU745545B2/en not_active Ceased
- 1999-07-15 SI SI9930178T patent/SI1077945T1/xx unknown
- 1999-07-15 ID IDW20010169D patent/ID26993A/id unknown
- 1999-07-15 ES ES99928177T patent/ES2189434T3/es not_active Expired - Lifetime
- 1999-07-15 EP EP99928177A patent/EP1077945B1/en not_active Expired - Lifetime
- 1999-07-15 CN CN99809025A patent/CN1318059A/zh active Pending
- 1999-07-15 DE DE69904814T patent/DE69904814T2/de not_active Expired - Fee Related
- 1999-07-15 CA CA002337247A patent/CA2337247A1/en not_active Abandoned
- 1999-07-15 HU HU0103665A patent/HUP0103665A3/hu unknown
- 1999-07-15 JP JP2000561170A patent/JP2002521367A/ja active Pending
- 1999-07-15 TR TR2001/00222T patent/TR200100222T2/xx unknown
- 1999-07-15 SK SK106-2001A patent/SK1062001A3/sk unknown
- 1999-07-16 HN HN1999000116A patent/HN1999000116A/es unknown
- 1999-07-21 MA MA25695A patent/MA26664A1/fr unknown
- 1999-07-21 TN TNTNSN99149A patent/TNSN99149A1/fr unknown
- 1999-07-21 DZ DZ990152A patent/DZ2852A1/xx active
- 1999-07-21 PE PE1999000733A patent/PE20000937A1/es not_active Application Discontinuation
- 1999-07-22 AR ARP990103614A patent/AR018960A1/es not_active Application Discontinuation
- 1999-07-23 PA PA19998478901A patent/PA8478901A1/es unknown
- 1999-07-23 GT GT199900116A patent/GT199900116A/es unknown
- 1999-07-23 TW TW088112548A patent/TW530049B/zh active
- 1999-07-26 CO CO99047012A patent/CO5080787A1/es unknown
- 1999-08-16 UY UY25663A patent/UY25663A1/es unknown
-
2000
- 2000-12-22 IS IS5789A patent/IS5789A/is unknown
-
2001
- 2001-01-09 ZA ZA200100230A patent/ZA200100230B/en unknown
- 2001-01-23 HR HR20010059A patent/HRP20010059A2/hr not_active Application Discontinuation
- 2001-01-23 NO NO20010400A patent/NO20010400L/no not_active Application Discontinuation
- 2001-02-14 BG BG105252A patent/BG105252A/xx unknown
-
2002
- 2002-04-10 HK HK02102712.1A patent/HK1040996A1/zh unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0200355A2 (en) | 4-aminopyrrolopyrimidines as kinase inhibitors, pharmaceutical compositions containing them and their use | |
| HUP0104060A3 (en) | Benzamide derivatives and their use as cytokine inhibitors, process for their preparation and medicaments containing them | |
| IL138280A0 (en) | 20-KETO-11β-ARYLSTERIODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR THE PREPARATION THEREOF | |
| HUP0200396A3 (en) | Gluckokinase activators, process for their preparation, pharmaceutical compositions containing them and their use | |
| HUP0105136A3 (en) | Amide derivatives, process for their preparation and medicaments containing them | |
| HUP0103884A3 (en) | Arylsulfonanilide urea-derivatives, pharmaceutical compositions containing them and their use | |
| HUP0103851A3 (en) | Factor viia inhibitors, process for their preparation, their use and pharmaceutical compositions comprising thereof | |
| HUP0204081A3 (en) | 4-pyrimidinyl-n-acyl-l-phenylalanines, pharmaceutical compositions containing them and their use | |
| HUP0201953A3 (en) | Benzene derivatives, preparation method and pharmaceutical compositions containing same | |
| PL343512A1 (en) | Thienylazolylalcoxyethanamines, their preparation and their application as medicaments | |
| HUP0003608A2 (en) | Tetrahydroisoquinoline derivatives, process for producing them and pharmaceutical compositions containing them | |
| HUP0203194A3 (en) | Phenylpiperazines, pharmaceutical compositions containing them and their use | |
| HUP0203735A3 (en) | 4-pyridinyl-n-acyl-l-phenylalanines, pharmaceutical compositions containing them and their use | |
| HUP0201402A3 (en) | Bis-sulfonamides, process for their preparation and pharmaceutical compositions containing them | |
| HUP0102215A3 (en) | Benzoylpyridazines, pharmaceutical compositions containing the same and process for their preparation | |
| PL340035A1 (en) | Isoquinolines as urokinase inhibitors | |
| HK1039122A1 (zh) | 取代的6-苄基-4-氧代嘧啶，其製備方法以及含該化合物的藥物組合物 | |
| HUP0103316A3 (en) | 2-ureido-pyrimidone derivatives, method for producing them, pharmaceutical compositions containing them and their use | |
| HUP0104620A3 (en) | 2-phenylpyran-4-one derivatives, process for their preparation and medicaments containing them | |
| AU3560601A (en) | Novel isoquinoline derivatives, preparation method and pharmaceutical compositions containing them | |
| ZA200006020B (en) | Voacamine as anti-malarial agent and anti-malarial agent containing voacamine. | |
| HUP0103665A3 (en) | Isoquinolines as urokinase inhibitors, peocess for their preparation and medicaments containing them | |
| HUP0103184A3 (en) | Sulfonyl-biphenyl-methyl-substituted imidazole derivatives, their use and pharmaceutical compositions containing them | |
| HUP0104202A3 (en) | Thiazole-derivatives, process for their preparation and pharmaceutical compositions containing them | |
| HUP0102773A3 (en) | Tetrahydronaphthyridinil-carboxamides having anti-convulsant activity, process for their preparation and pharmaceutical compositions containing the same |