HUP0103064A3 - Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing it - Google Patents
Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing itInfo
- Publication number
- HUP0103064A3 HUP0103064A3 HU0103064A HUP0103064A HUP0103064A3 HU P0103064 A3 HUP0103064 A3 HU P0103064A3 HU 0103064 A HU0103064 A HU 0103064A HU P0103064 A HUP0103064 A HU P0103064A HU P0103064 A3 HUP0103064 A3 HU P0103064A3
- Authority
- HU
- Hungary
- Prior art keywords
- piridazinone
- propylamino
- fumarate
- dimethoxy
- chloro
- Prior art date
Links
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/22—Nitrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Treating Waste Gases (AREA)
- Photoreceptors In Electrophotography (AREA)
- Silver Salt Photography Or Processing Solution Therefor (AREA)
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0103064A HUP0103064A3 (en) | 2001-07-26 | 2001-07-26 | Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing it |
SK54-2004A SK542004A3 (en) | 2001-07-26 | 2002-07-26 | Polymorph salt of a pyridazinone derivative for the treatment arrhythmia |
PCT/HU2002/000076 WO2003010150A1 (en) | 2001-07-26 | 2002-07-26 | Polymorph salt of a pyridazinone derivative for the treatment of arrythmia |
IL15996702A IL159967A0 (en) | 2001-07-26 | 2002-07-26 | Polymorph salt of a pyridazinone derivative for the treatment of arrythmia |
YU7604A YU7604A (sh) | 2001-07-26 | 2002-07-26 | Polimorf soli derivata piridazinona za tretman aritmije |
EA200400222A EA200400222A1 (ru) | 2001-07-26 | 2002-07-26 | Полиморфная соль производного пиридазинона для лечения аритмии |
CZ2004124A CZ2004124A3 (cs) | 2001-07-26 | 2002-07-26 | Název neuveden |
EP02755384A EP1417179A1 (en) | 2001-07-26 | 2002-07-26 | Polymorph salt of a pyridazinone derivative for the treatment of arrhythmia |
US10/484,621 US20040266772A1 (en) | 2001-07-26 | 2002-07-26 | Polymorph salt of a pryridazinone derivative for the treatment of arrythmia |
PL02365483A PL365483A1 (en) | 2001-07-26 | 2002-07-26 | Polymorph salt of a pyridazinone derivative for the treatment of arrythmia |
CNA028162587A CN1545505A (zh) | 2001-07-26 | 2002-07-26 | 用于治疗心律失常的哒嗪酮衍生物的多晶型盐 |
JP2003515509A JP2004536868A (ja) | 2001-07-26 | 2002-07-26 | 不整脈治療用のピリダジノン誘導体の多形体塩 |
CA002454774A CA2454774A1 (en) | 2001-07-26 | 2002-07-26 | Polymorph salt of a pyridazinone derivative for the treatment of arrythmia |
KR10-2004-7001150A KR20040030861A (ko) | 2001-07-26 | 2002-07-26 | 부정맥 치료용의 피리다지논 유도체의 다형 염 |
ZA200400483A ZA200400483B (en) | 2001-07-26 | 2004-01-22 | Polymorph salt of a pyridazinone derivative for the treatment of arrythmia. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0103064A HUP0103064A3 (en) | 2001-07-26 | 2001-07-26 | Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing it |
Publications (3)
Publication Number | Publication Date |
---|---|
HU0103064D0 HU0103064D0 (en) | 2001-10-28 |
HUP0103064A2 HUP0103064A2 (hu) | 2003-02-28 |
HUP0103064A3 true HUP0103064A3 (en) | 2005-06-28 |
Family
ID=89979563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0103064A HUP0103064A3 (en) | 2001-07-26 | 2001-07-26 | Polymorphic form of 5-chloro-4-(3-{[2-(3,4-dimethoxy-phenyl)-ethyl]-methyl-amino]-propylamino)-3-(2h)-piridazinone fumarate, its use, process for its preparation and pharmaceutical compositions containing it |
Country Status (15)
Country | Link |
---|---|
US (1) | US20040266772A1 (hu) |
EP (1) | EP1417179A1 (hu) |
JP (1) | JP2004536868A (hu) |
KR (1) | KR20040030861A (hu) |
CN (1) | CN1545505A (hu) |
CA (1) | CA2454774A1 (hu) |
CZ (1) | CZ2004124A3 (hu) |
EA (1) | EA200400222A1 (hu) |
HU (1) | HUP0103064A3 (hu) |
IL (1) | IL159967A0 (hu) |
PL (1) | PL365483A1 (hu) |
SK (1) | SK542004A3 (hu) |
WO (1) | WO2003010150A1 (hu) |
YU (1) | YU7604A (hu) |
ZA (1) | ZA200400483B (hu) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU227181B1 (en) * | 2002-09-11 | 2010-09-28 | Egis Gyogyszergyar Nyilvanosan | Use of 5-chloro-4-[3-[n-[2-(3,4-dimethoxyphenyl)ethyl)]-n-methylamino]-propylamino]-3-(2h)-pyridazinone for producing pharmaceutical compositions having metabolic modulator effect |
HU227115B1 (en) * | 2003-10-10 | 2010-07-28 | Egis Gyogyszergyar Nyilvanosan | Pellets containing pyridazinone derivative |
GB201105537D0 (en) * | 2011-03-31 | 2011-05-18 | Vantia Ltd | New process |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU214320B (hu) * | 1991-12-20 | 1998-03-02 | EGIS Gyógyszergyár Rt. | Eljárás új 3(2H)-piridazinon-származékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
BR9815967A (pt) * | 1998-06-05 | 2004-06-22 | Egyt Gyogyszervegyeszeti Gyar | Processo para a preparação de um derivado de amino-5-cloro de 3(2h)-piridazinona-4-substituìdo |
-
2001
- 2001-07-26 HU HU0103064A patent/HUP0103064A3/hu unknown
-
2002
- 2002-07-26 SK SK54-2004A patent/SK542004A3/sk not_active Application Discontinuation
- 2002-07-26 KR KR10-2004-7001150A patent/KR20040030861A/ko not_active Application Discontinuation
- 2002-07-26 EP EP02755384A patent/EP1417179A1/en not_active Withdrawn
- 2002-07-26 IL IL15996702A patent/IL159967A0/xx unknown
- 2002-07-26 CN CNA028162587A patent/CN1545505A/zh active Pending
- 2002-07-26 PL PL02365483A patent/PL365483A1/xx unknown
- 2002-07-26 EA EA200400222A patent/EA200400222A1/ru unknown
- 2002-07-26 JP JP2003515509A patent/JP2004536868A/ja active Pending
- 2002-07-26 WO PCT/HU2002/000076 patent/WO2003010150A1/en not_active Application Discontinuation
- 2002-07-26 YU YU7604A patent/YU7604A/sh unknown
- 2002-07-26 CZ CZ2004124A patent/CZ2004124A3/cs unknown
- 2002-07-26 CA CA002454774A patent/CA2454774A1/en not_active Abandoned
- 2002-07-26 US US10/484,621 patent/US20040266772A1/en not_active Abandoned
-
2004
- 2004-01-22 ZA ZA200400483A patent/ZA200400483B/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2004536868A (ja) | 2004-12-09 |
CA2454774A1 (en) | 2003-02-06 |
PL365483A1 (en) | 2005-01-10 |
CN1545505A (zh) | 2004-11-10 |
EA200400222A1 (ru) | 2004-12-30 |
SK542004A3 (en) | 2004-08-03 |
YU7604A (sh) | 2006-08-17 |
KR20040030861A (ko) | 2004-04-09 |
CZ2004124A3 (cs) | 2004-06-16 |
ZA200400483B (en) | 2005-04-22 |
EP1417179A1 (en) | 2004-05-12 |
HUP0103064A2 (hu) | 2003-02-28 |
WO2003010150A1 (en) | 2003-02-06 |
HU0103064D0 (en) | 2001-10-28 |
US20040266772A1 (en) | 2004-12-30 |
IL159967A0 (en) | 2004-06-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC9A | Change of name, address |
Owner name: EGIS GYOGYSZERGYAR NYILVANOSAN MUEKOEDOE RESZV, HU Free format text: FORMER OWNER(S): EGIS GYOGYSZERGYAR RT., HU |
|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |