HUP0102704A2 - Meiózist befolyásoló szteroidok és alkalmazásuk - Google Patents

Meiózist befolyásoló szteroidok és alkalmazásuk

Info

Publication number
HUP0102704A2
HUP0102704A2 HU0102704A HUP0102704A HUP0102704A2 HU P0102704 A2 HUP0102704 A2 HU P0102704A2 HU 0102704 A HU0102704 A HU 0102704A HU P0102704 A HUP0102704 A HU P0102704A HU P0102704 A2 HUP0102704 A2 HU P0102704A2
Authority
HU
Hungary
Prior art keywords
steroid compounds
meiosis
derivatives
meiosis regulating
regulating steroid
Prior art date
Application number
HU0102704A
Other languages
English (en)
Inventor
Peter Faarup
Anthony Murray
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of HUP0102704A2 publication Critical patent/HUP0102704A2/hu
Publication of HUP0102704A3 publication Critical patent/HUP0102704A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány tárgyát képezik (Ia) általános képletű újszterolszármazékok, ahol a szubsztituensek különböző csoportokatjelentenek, és amelyekre jellemző, hogy a 3-as helyen nem hordoznakhidroxilcsoportot. Ezek a származékok befolyásolni (serkenteni vagygátolni) képesek az emlős csírasejtek meiózisát, ezáltalfelhasználhatók a nő- vagy hímivarú emlősök, előnyösen az emberterméketlenségének kezelésére, illetve fogamzásgátlókéntalkalmazhatók. Ó
HU0102704A 1998-06-19 1999-06-18 Meiosis regulating steroid compounds and use thereof HUP0102704A3 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
DK80798 1998-06-19
DK81098 1998-06-19
US9276398P 1998-07-14 1998-07-14
US9302598P 1998-07-16 1998-07-16
DKPA199900140 1999-02-04
DKPA199900141 1999-02-04
PCT/DK1999/000333 WO1999067273A1 (en) 1998-06-19 1999-06-18 Meiosis regulating compounds

Publications (2)

Publication Number Publication Date
HUP0102704A2 true HUP0102704A2 (hu) 2002-01-28
HUP0102704A3 HUP0102704A3 (en) 2002-09-30

Family

ID=27545144

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102704A HUP0102704A3 (en) 1998-06-19 1999-06-18 Meiosis regulating steroid compounds and use thereof

Country Status (9)

Country Link
US (1) US20020007079A1 (hu)
EP (1) EP1087988A1 (hu)
JP (1) JP2003521444A (hu)
KR (1) KR20010053031A (hu)
AU (1) AU4498299A (hu)
CA (1) CA2335329A1 (hu)
HU (1) HUP0102704A3 (hu)
IL (1) IL140216A0 (hu)
WO (1) WO1999067273A1 (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ303171B6 (cs) * 2009-11-04 2012-05-09 Ústav organické chemie a biochemie Akademie ved Ceské republiky, v. v. i. Použití cholestanových derivátu k výrobe léciva pro lécbu nádorového bujení a s ním spojené angiogeneze
JP6353939B1 (ja) * 2017-02-15 2018-07-04 横関油脂工業株式会社 油状組成物、その製法、油性基剤および皮膚外用剤
WO2022241404A1 (en) * 2021-05-11 2022-11-17 Trustees Of Dartmouth College Liver x receptor modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
KR19980702624A (ko) * 1995-03-06 1998-08-05 슈타르 피아 감수분열의 자극
CA2224866A1 (en) * 1995-06-23 1997-01-09 Novo Nordisk A/S Meiosis regulating compounds
AU746878B2 (en) * 1996-12-20 2002-05-02 Novo Nordisk A/S Meiosis regulating compounds
KR20010012643A (ko) * 1997-05-16 2001-02-26 에프.지.엠. 헤르만스 20-아랄킬-5α-프레그난 유도체
EP0988312B1 (en) * 1997-06-04 2002-04-03 Akzo Nobel N.V. 17beta-allyloxy(thio)alkyl-androstane derivatives for the modulation of meiosis

Also Published As

Publication number Publication date
WO1999067273A1 (en) 1999-12-29
KR20010053031A (ko) 2001-06-25
EP1087988A1 (en) 2001-04-04
JP2003521444A (ja) 2003-07-15
CA2335329A1 (en) 1999-12-29
AU4498299A (en) 2000-01-10
HUP0102704A3 (en) 2002-09-30
IL140216A0 (en) 2002-02-10
US20020007079A1 (en) 2002-01-17

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