ATE245196T1 - Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor beta - Google Patents
Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor betaInfo
- Publication number
- ATE245196T1 ATE245196T1 AT94911509T AT94911509T ATE245196T1 AT E245196 T1 ATE245196 T1 AT E245196T1 AT 94911509 T AT94911509 T AT 94911509T AT 94911509 T AT94911509 T AT 94911509T AT E245196 T1 ATE245196 T1 AT E245196T1
- Authority
- AT
- Austria
- Prior art keywords
- growth factor
- transforming growth
- factor beta
- fertility
- regulation
- Prior art date
Links
- 102000004887 Transforming Growth Factor beta Human genes 0.000 title abstract 2
- 108090001012 Transforming Growth Factor beta Proteins 0.000 title abstract 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 title abstract 2
- 230000035558 fertility Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 208000007984 Female Infertility Diseases 0.000 abstract 1
- 206010021928 Infertility female Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 238000002513 implantation Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
- G01N2333/495—Transforming growth factor [TGF]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/367—Infertility, e.g. sperm disorder, ovulatory dysfunction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/806—Fertility tests
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/814—Pregnancy
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/906—Fertility tests
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Pregnancy & Childbirth (AREA)
- Gastroenterology & Hepatology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Gynecology & Obstetrics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/029,027 US5395825A (en) | 1993-03-10 | 1993-03-10 | Fertility regulation with transforming growth factor β |
| PCT/US1994/002527 WO1994020637A1 (en) | 1993-03-10 | 1994-03-08 | Fertility regulation with transforming growth factor beta |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE245196T1 true ATE245196T1 (de) | 2003-08-15 |
Family
ID=21846834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94911509T ATE245196T1 (de) | 1993-03-10 | 1994-03-08 | Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor beta |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5395825A (de) |
| EP (1) | EP0688365B1 (de) |
| JP (1) | JPH08507530A (de) |
| AT (1) | ATE245196T1 (de) |
| AU (1) | AU676727B2 (de) |
| CA (1) | CA2156613A1 (de) |
| DE (1) | DE69432951T2 (de) |
| DK (1) | DK0688365T3 (de) |
| WO (1) | WO1994020637A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5508045A (en) * | 1992-10-09 | 1996-04-16 | The Regents Of The University Of California | Method and agents for control and management of labor during pregnancy |
| US5830848A (en) * | 1992-10-09 | 1998-11-03 | The Regents Of The University Of California | Method and agents for inducement of endogenous nitric oxide synthase for control and management of labor during pregnancy |
| US5395825A (en) * | 1993-03-10 | 1995-03-07 | Yale University | Fertility regulation with transforming growth factor β |
| US5599918A (en) * | 1994-10-04 | 1997-02-04 | La Jolla Cancer Research Foundation | Nucleic acids encoding trophinin and trophinin-assisting proteins |
| US5654145A (en) * | 1994-10-04 | 1997-08-05 | La Jolla Cancer Research Foundation | Trophinin and trophinin-assisting nucleic acids and methods of detection thereof |
| US6309843B1 (en) | 1994-10-25 | 2001-10-30 | The Curators Of The University Of Missouri | Glycoprotein for use in determining endometrial receptivity |
| US7211644B1 (en) * | 1996-08-27 | 2007-05-01 | University Of South Florida | Diagnostic markers of human female infertility |
| US6683156B1 (en) | 1996-08-27 | 2004-01-27 | University Of South Florida | Method for diagnosing selected adenocarcinomas |
| US8106001B2 (en) * | 1996-08-27 | 2012-01-31 | University Of South Florida | Diagnostic markers of human female infertility |
| US6294662B1 (en) | 1996-08-27 | 2001-09-25 | University Of South Florida | Nucleic acids encoding an endometrial bleeding associated factor (ebaf) |
| AUPO550897A0 (en) * | 1997-03-06 | 1997-03-27 | Luminis Pty Limited | Treatment and diagnosis of an infertility condition |
| AU722150B2 (en) * | 1997-03-06 | 2000-07-20 | University Of Adelaide, The | Treatment and diagnosis of infertility using TGFbeta or activin |
| US6300311B1 (en) | 1998-04-14 | 2001-10-09 | Texas Tech University | Regulation of vertebrate ovarian maturation and function using growth factors |
| AU3671499A (en) * | 1998-04-29 | 1999-11-16 | University Of South Florida | Diagnostic markers of human female infertility |
| GB0201284D0 (en) * | 2002-01-21 | 2002-03-06 | Isis Innovation | Screening methods for contraceptive and fertility agents |
| US7572639B2 (en) * | 2004-06-03 | 2009-08-11 | Stc.Unm | Method and apparatus for predicting pregnancy outcome |
| CA2575675A1 (en) | 2004-07-30 | 2006-03-09 | Adeza Biomedical Corporation | Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin |
| WO2011002251A2 (ko) * | 2009-07-01 | 2011-01-06 | 중앙대학교 산학협력단 | 수태능력 예측용 마커 |
| GB201314452D0 (en) * | 2013-08-13 | 2013-09-25 | Ostara Biomedical Ltd | Embryo implantation |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5104977A (en) * | 1982-09-24 | 1992-04-14 | The United States Of America As Represented By The Department Of Health And Human Services | Purified transforming growth factor beta |
| US4894326A (en) * | 1986-04-09 | 1990-01-16 | Fred Hutchinson Cancer Research Center | Monoclonal antibody defining oncofetal structure of fibronectin |
| US5098890A (en) * | 1988-11-07 | 1992-03-24 | Temple University-Of The Commonwealth System Of Higher Education | Antisence oligonucleotides to c-myb proto-oncogene and uses thereof |
| US5158934A (en) * | 1989-09-01 | 1992-10-27 | Genentech, Inc. | Method of inducing bone growth using TGF-β |
| FI921353A7 (fi) * | 1989-09-29 | 1992-03-27 | La Jolla Cancer Res Foundation | Tranformoiva kasvutekijä b:n inhibointi solunulkoisen matriisin kertym isen ehkäisemiseksi |
| US5276017A (en) * | 1990-09-14 | 1994-01-04 | Trustees Of The University Of Pennsylvania | Therapeutic and diagnostic applications of tropho-uteronectin (TUN) manipulation |
| US5395825A (en) * | 1993-03-10 | 1995-03-07 | Yale University | Fertility regulation with transforming growth factor β |
| FR2720069A1 (fr) * | 1994-05-19 | 1995-11-24 | Inst Nat Sante Rech Med | Dérivés de facteurs de croissance et d'hormones de la superfamille des TGFB, procédé pour leur obtention et leurs applications biologiques. |
-
1993
- 1993-03-10 US US08/029,027 patent/US5395825A/en not_active Expired - Fee Related
-
1994
- 1994-03-08 DE DE69432951T patent/DE69432951T2/de not_active Expired - Fee Related
- 1994-03-08 CA CA002156613A patent/CA2156613A1/en not_active Abandoned
- 1994-03-08 JP JP6520281A patent/JPH08507530A/ja not_active Ceased
- 1994-03-08 WO PCT/US1994/002527 patent/WO1994020637A1/en not_active Ceased
- 1994-03-08 AT AT94911509T patent/ATE245196T1/de not_active IP Right Cessation
- 1994-03-08 DK DK94911509T patent/DK0688365T3/da active
- 1994-03-08 EP EP94911509A patent/EP0688365B1/de not_active Expired - Lifetime
- 1994-03-08 AU AU63998/94A patent/AU676727B2/en not_active Ceased
- 1994-12-13 US US08/354,671 patent/US5693479A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2156613A1 (en) | 1994-09-15 |
| WO1994020637A1 (en) | 1994-09-15 |
| AU676727B2 (en) | 1997-03-20 |
| EP0688365B1 (de) | 2003-07-16 |
| US5395825A (en) | 1995-03-07 |
| AU6399894A (en) | 1994-09-26 |
| EP0688365A1 (de) | 1995-12-27 |
| JPH08507530A (ja) | 1996-08-13 |
| DK0688365T3 (da) | 2003-09-29 |
| DE69432951D1 (de) | 2003-08-21 |
| EP0688365A4 (de) | 1997-06-25 |
| DE69432951T2 (de) | 2004-05-13 |
| US5693479A (en) | 1997-12-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE245196T1 (de) | Regulierung der fruchtbarkeit mit transformierendem wachstumfaktor beta | |
| MY102705A (en) | Proline derivaties and related compounds. | |
| YU48666B (sh) | Mometason furoat monohidrat i postupak za njegovo dobijanje | |
| IL110672A0 (en) | Therapeutic heterocycles | |
| AU2332288A (en) | Compounds having antiprogestational and anti-estrogenic activities for induction of labor and for termination of pregnancy, as well as for the treatment of gynaecological disorders | |
| ES2124250T3 (es) | Anticuerpo especifico para un antigeno tumoral. | |
| ES466793A1 (es) | Un procedimiento para la preparacion de derivados de imida- zol, con propiedades antiartriticas. | |
| GR890100033A (el) | Μέ?οδος παρασκευής διδεοξυδιδευδροκαρβοκυκλικών νουκλεοσιδών. | |
| UA32409C2 (uk) | Згинальний пристрій | |
| BG40815A3 (bg) | Метод за получаване на пептиди | |
| ES533261A0 (es) | Procedimiento para la preparacion de 1-alquil-androsta-1,4-dien-3,17-dionas | |
| SE8003263L (sv) | Ledbeslag for seten med instellbar lutning, serskilt fordonsseten | |
| ES2109103T3 (es) | Procedimiento para la preparacion de trialquilsilil-7 bacatina iii. | |
| BG36928A3 (bg) | Метод за получаване на фармакологично активни пептиди | |
| GB1531176A (en) | Hydrogenated imidazothiazine derivatives | |
| MX9303843A (es) | 4-iminoquinolinas, procedimiento para su preparacion y su empleo. | |
| ES2099820T3 (es) | Procedimiento para la preparacion de trans-piperidina-2,5-dicarboxilatos. | |
| ES2165350T3 (es) | Descarboxilasa de acido glutamico clonada. | |
| ATE227122T1 (de) | Stabilisierte tablettenformulierung | |
| ES8704469A1 (es) | Procedimiento para preparar naftoxacinas | |
| ES8205218A1 (es) | Un procedimiento para la preparacion de pirrolilpiperidinas utiles como agentes antidepresivo. | |
| GR3005231T3 (de) | ||
| MX9300677A (es) | Procedimiento mejorado para la preparacion de dienos esteroidales substituidos. | |
| SU887878A1 (ru) | Демпфирующее устройство | |
| FI890173L (fi) | Isoxazoler med nootropisk verkan. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |