HUP0102124A2 - Eljárás 2-acetiltio-3-fenil-propionsav és sói előállítására - Google Patents
Eljárás 2-acetiltio-3-fenil-propionsav és sói előállításáraInfo
- Publication number
- HUP0102124A2 HUP0102124A2 HU0102124A HUP0102124A HUP0102124A2 HU P0102124 A2 HUP0102124 A2 HU P0102124A2 HU 0102124 A HU0102124 A HU 0102124A HU P0102124 A HUP0102124 A HU P0102124A HU P0102124 A2 HUP0102124 A2 HU P0102124A2
- Authority
- HU
- Hungary
- Prior art keywords
- acetylthio
- salts
- phenyl
- preparing
- propionic acid
- Prior art date
Links
- UOVSNFYJYANSNI-UHFFFAOYSA-N 2-acetylsulfanyl-3-phenylpropanoic acid Chemical compound CC(=O)SC(C(O)=O)CC1=CC=CC=C1 UOVSNFYJYANSNI-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 title abstract 2
- JYWKEVKEKOTYEX-UHFFFAOYSA-N 2,6-dibromo-4-chloroiminocyclohexa-2,5-dien-1-one Chemical compound ClN=C1C=C(Br)C(=O)C(Br)=C1 JYWKEVKEKOTYEX-UHFFFAOYSA-N 0.000 abstract 1
- WDRSCFNERFONKU-UHFFFAOYSA-N 2-bromo-3-phenylpropanoic acid Chemical compound OC(=O)C(Br)CC1=CC=CC=C1 WDRSCFNERFONKU-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000003444 phase transfer catalyst Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
A találmány a 2-acetil-tio-3-fenil-propionsav és sói előállításieljárására vonatkozik 2-bróm-3-fenil-propionsavból és kálium-tioacetátból kiindulva, szerves oldószerben és egy fázistranszferkatalizátor jelenlétében. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT98MI000301A IT1298267B1 (it) | 1998-02-18 | 1998-02-18 | Procedimento per la preparazione dell'acido (s)-2-acetiltio-3-fenil- propionico e dei suoi sali |
PCT/EP1999/000467 WO1999042438A1 (en) | 1998-02-18 | 1999-01-26 | Process for preparing 2-acetylthio-3-phenyl-propionic acid and the salts thereof |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0102124A2 true HUP0102124A2 (hu) | 2002-03-28 |
HUP0102124A3 HUP0102124A3 (en) | 2002-12-28 |
HU223325B1 HU223325B1 (hu) | 2004-06-28 |
Family
ID=11378966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0102124A HU223325B1 (hu) | 1998-02-18 | 1999-01-26 | Eljárás 2-acetiltio-3-fenil-propionsav és sói előállítására |
Country Status (11)
Country | Link |
---|---|
US (1) | US6080881A (hu) |
EP (1) | EP1056715B1 (hu) |
AT (1) | ATE219052T1 (hu) |
CA (1) | CA2321294A1 (hu) |
DE (1) | DE69901792T2 (hu) |
ES (1) | ES2177247T3 (hu) |
HU (1) | HU223325B1 (hu) |
IL (1) | IL137119A (hu) |
IT (1) | IT1298267B1 (hu) |
WO (1) | WO1999042438A1 (hu) |
ZA (1) | ZA99814B (hu) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL1014354C2 (nl) * | 2000-02-11 | 2001-08-14 | Dsm Nv | Werkwijze voor de bereiding van (S) -2-acethylthio-3-fenylpropaanzuur. |
ES2227069T3 (es) * | 2000-03-30 | 2005-04-01 | Ajinomoto Co., Inc. | Metodo de produccion de un derivado de acido acetiltiocarboxilico aromatico. |
US6596870B2 (en) | 2000-07-13 | 2003-07-22 | Brandeis University | Asymmetric synthetic methods based on phase transfer catalysis |
US6620600B2 (en) * | 2000-09-15 | 2003-09-16 | Bristol-Myers Squibb Co. | Enzymatic resolution of aryl and thio-substituted acids |
DE10212198A1 (de) * | 2002-03-19 | 2003-10-02 | Aventis Pharma Gmbh | Ethan-1-diaminium-bis(2R)-2-brom-3-phenylpropanoat), Verfahren zu dessen Herstellung und dessen Verwendung |
US7009047B2 (en) | 2002-03-19 | 2006-03-07 | Sanofi-Aventis Deutschland Gmbh | Ethane-1,2-diaminium bis[(2R)-2-bromo-3-phenylpropanoate], processes for its preparation and its use |
US7317124B2 (en) | 2003-11-13 | 2008-01-08 | Sanofi-Aventis Deutschland Gmbh | Ortho-substituted pentafluorosulfanylbenzenes, process for their preparation and their use as valuable synthetic intermediates |
CN105418495B (zh) * | 2015-11-25 | 2018-09-14 | 乳源瑶族自治县大众药品贸易有限公司 | 一种硫醚的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4339600A (en) * | 1976-05-10 | 1982-07-13 | E. R. Squibb & Sons, Inc. | Compounds for alleviating angiotensin related hypertension |
IT1122202B (it) * | 1979-07-17 | 1986-04-23 | Alcar Srl | Processo per la preparazione di acidi alfa-aril propionici |
FR2679564A1 (fr) * | 1991-07-23 | 1993-01-29 | Inst Nat Sante Rech Med | Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent. |
US5504080A (en) * | 1992-10-28 | 1996-04-02 | Bristol-Myers Squibb Co. | Benzo-fused lactams |
JPH06320363A (ja) * | 1993-05-19 | 1994-11-22 | Ricoh Co Ltd | 部品自動組立装置 |
US5508272A (en) * | 1993-06-15 | 1996-04-16 | Bristol-Myers Squibb Company | Compounds containing a fused bicycle ring and processes therefor |
US5525723A (en) * | 1993-11-18 | 1996-06-11 | Bristol-Myers Squibb Co. | Compounds containing a fused multiple ring lactam |
-
1998
- 1998-02-18 IT IT98MI000301A patent/IT1298267B1/it active IP Right Grant
-
1999
- 1999-01-26 HU HU0102124A patent/HU223325B1/hu not_active IP Right Cessation
- 1999-01-26 AT AT99907415T patent/ATE219052T1/de not_active IP Right Cessation
- 1999-01-26 ES ES99907415T patent/ES2177247T3/es not_active Expired - Lifetime
- 1999-01-26 DE DE69901792T patent/DE69901792T2/de not_active Expired - Fee Related
- 1999-01-26 CA CA002321294A patent/CA2321294A1/en not_active Abandoned
- 1999-01-26 WO PCT/EP1999/000467 patent/WO1999042438A1/en active IP Right Grant
- 1999-01-26 EP EP99907415A patent/EP1056715B1/en not_active Expired - Lifetime
- 1999-01-26 IL IL13711999A patent/IL137119A/xx active IP Right Grant
- 1999-02-02 ZA ZA9900814A patent/ZA99814B/xx unknown
- 1999-02-17 US US09/251,468 patent/US6080881A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1056715A1 (en) | 2000-12-06 |
CA2321294A1 (en) | 1999-08-26 |
HU223325B1 (hu) | 2004-06-28 |
EP1056715B1 (en) | 2002-06-12 |
ZA99814B (en) | 1999-08-02 |
IT1298267B1 (it) | 1999-12-20 |
IL137119A0 (en) | 2001-06-14 |
ES2177247T3 (es) | 2002-12-01 |
IL137119A (en) | 2005-07-25 |
WO1999042438A1 (en) | 1999-08-26 |
ATE219052T1 (de) | 2002-06-15 |
US6080881A (en) | 2000-06-27 |
ITMI980301A1 (it) | 1999-08-18 |
HUP0102124A3 (en) | 2002-12-28 |
DE69901792D1 (de) | 2002-07-18 |
DE69901792T2 (de) | 2003-02-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20040419 |
|
MM4A | Lapse of definitive patent protection due to non-payment of fees |