HUP0101931A2 - Paroxetint tartalmazó új készítmény - Google Patents
Paroxetint tartalmazó új készítményInfo
- Publication number
- HUP0101931A2 HUP0101931A2 HU0101931A HUP0101931A HUP0101931A2 HU P0101931 A2 HUP0101931 A2 HU P0101931A2 HU 0101931 A HU0101931 A HU 0101931A HU P0101931 A HUP0101931 A HU P0101931A HU P0101931 A2 HUP0101931 A2 HU P0101931A2
- Authority
- HU
- Hungary
- Prior art keywords
- hemihydrate
- conditions
- formulation containing
- novel formulation
- detectable
- Prior art date
Links
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 title abstract 4
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229960002296 paroxetine Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 229960005183 paroxetine hydrochloride Drugs 0.000 abstract 2
- 229910052925 anhydrite Inorganic materials 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 abstract 1
- 239000012051 hydrophobic carrier Substances 0.000 abstract 1
- -1 paroxetine hydrochloride anhydride Chemical class 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
A tal lm ny egy, a hemihidr ttól eltérő form ban lévő paroxetin-hidrokloridra vonatkozik, amelyet olyan k"rülmények k"z"tt form lnakkapszul kba, amely k"rülmények k"z"tt az elő llít si elj r s sor nnincs detekt lható mértékű hemihidr tt t"rténő talakul s. A tal lm nyt rgy t képezi tov bb egy elj r s detekt lható hemihidr ttól mentesparoxetin-hidroklorid-anhidr t kapszul k elő llít s ra, amelynek sor nolyan k"rülményeket alkalmaznak, amely k"rülmények k"z"tt az elő llítsi elj r s sor n nem lép fel detekt lható mértékű anhidr tból hemihidrtt t"rténő talakul s. Ilyen k"rülményeket úgy biztosítanak, hogyalacsony relatív p ratartalom mellett lényegében vízmentes és/vagyhidrofób vivőanyagokat alkalmaznak. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9810180.1A GB9810180D0 (en) | 1998-05-13 | 1998-05-13 | Novel formulation |
| PCT/GB1999/001522 WO1999058116A2 (en) | 1998-05-13 | 1999-05-13 | Novel formulation containing paroxetine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0101931A2 true HUP0101931A2 (hu) | 2002-04-29 |
| HUP0101931A3 HUP0101931A3 (en) | 2002-10-28 |
Family
ID=10831926
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0101931A HUP0101931A3 (en) | 1998-05-13 | 1999-05-13 | Novel formulation containing paroxetine |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1077685A2 (hu) |
| JP (1) | JP2002514593A (hu) |
| KR (1) | KR20010043545A (hu) |
| CN (1) | CN1309557A (hu) |
| AP (1) | AP2000001985A0 (hu) |
| AU (1) | AU3941099A (hu) |
| BG (1) | BG105011A (hu) |
| BR (1) | BR9910402A (hu) |
| CA (1) | CA2331849A1 (hu) |
| EA (1) | EA200001173A1 (hu) |
| GB (1) | GB9810180D0 (hu) |
| HU (1) | HUP0101931A3 (hu) |
| ID (1) | ID27018A (hu) |
| IL (1) | IL139596A0 (hu) |
| NO (1) | NO20005681L (hu) |
| PL (1) | PL344872A1 (hu) |
| SK (1) | SK16972000A3 (hu) |
| TR (1) | TR200003351T2 (hu) |
| WO (1) | WO1999058116A2 (hu) |
| ZA (1) | ZA200006465B (hu) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1161241B1 (de) * | 1999-03-12 | 2005-12-07 | Aesica Pharmaceuticals Ltd. | Stabile pharmazeutische anwendungsform für paroxetin-anhydrat |
| HU226912B1 (en) * | 2000-04-07 | 2010-03-01 | Richter Gedeon Nyrt | New paroxetin salt and medicament containing it |
| JP6062422B2 (ja) * | 2012-03-29 | 2017-01-18 | 杏林製薬株式会社 | カプセル製剤 |
| DE102013207447A1 (de) | 2013-04-24 | 2014-10-30 | Evonik Degussa Gmbh | Verfahren und Vorrichtung zur Herstellung von Octachlortrisilan |
| CN103520131B (zh) * | 2013-10-12 | 2019-05-14 | 浙江华海药业股份有限公司 | 盐酸帕罗西汀半水合物胶囊的制备方法 |
| CN103961333B (zh) * | 2014-05-07 | 2020-02-21 | 浙江华海药业股份有限公司 | 甲磺酸帕罗西汀胶囊及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996031197A1 (en) * | 1995-04-03 | 1996-10-10 | Abbott Laboratories | Homogeneous mixtures of low temperature-melting drugs and additives for controlled release |
| GB9724544D0 (en) * | 1997-11-21 | 1998-01-21 | Smithkline Beecham Plc | Novel Formulation |
-
1998
- 1998-05-13 GB GBGB9810180.1A patent/GB9810180D0/en not_active Ceased
-
1999
- 1999-05-13 PL PL99344872A patent/PL344872A1/xx unknown
- 1999-05-13 AU AU39410/99A patent/AU3941099A/en not_active Abandoned
- 1999-05-13 BR BR9910402-4A patent/BR9910402A/pt not_active Application Discontinuation
- 1999-05-13 TR TR2000/03351T patent/TR200003351T2/xx unknown
- 1999-05-13 KR KR1020007012660A patent/KR20010043545A/ko not_active Application Discontinuation
- 1999-05-13 EA EA200001173A patent/EA200001173A1/ru unknown
- 1999-05-13 JP JP2000547967A patent/JP2002514593A/ja active Pending
- 1999-05-13 AP APAP/P/2000/001985A patent/AP2000001985A0/en unknown
- 1999-05-13 CA CA002331849A patent/CA2331849A1/en not_active Abandoned
- 1999-05-13 IL IL13959699A patent/IL139596A0/xx unknown
- 1999-05-13 WO PCT/GB1999/001522 patent/WO1999058116A2/en not_active Application Discontinuation
- 1999-05-13 HU HU0101931A patent/HUP0101931A3/hu unknown
- 1999-05-13 SK SK1697-2000A patent/SK16972000A3/sk unknown
- 1999-05-13 CN CN99808548A patent/CN1309557A/zh active Pending
- 1999-05-13 EP EP99922303A patent/EP1077685A2/en not_active Withdrawn
- 1999-05-13 ID IDW20002329A patent/ID27018A/id unknown
-
2000
- 2000-11-09 ZA ZA200006465A patent/ZA200006465B/en unknown
- 2000-11-10 NO NO20005681A patent/NO20005681L/no not_active Application Discontinuation
- 2000-11-30 BG BG105011A patent/BG105011A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL344872A1 (en) | 2001-11-19 |
| NO20005681L (no) | 2000-12-01 |
| NO20005681D0 (no) | 2000-11-10 |
| WO1999058116A3 (en) | 2000-02-17 |
| AU3941099A (en) | 1999-11-29 |
| JP2002514593A (ja) | 2002-05-21 |
| KR20010043545A (ko) | 2001-05-25 |
| CA2331849A1 (en) | 1999-11-18 |
| ZA200006465B (en) | 2001-11-09 |
| BR9910402A (pt) | 2001-01-09 |
| IL139596A0 (en) | 2002-02-10 |
| EP1077685A2 (en) | 2001-02-28 |
| HUP0101931A3 (en) | 2002-10-28 |
| GB9810180D0 (en) | 1998-07-08 |
| BG105011A (en) | 2001-07-31 |
| WO1999058116A2 (en) | 1999-11-18 |
| CN1309557A (zh) | 2001-08-22 |
| TR200003351T2 (tr) | 2001-03-21 |
| EA200001173A1 (ru) | 2001-04-23 |
| AP2000001985A0 (en) | 2000-12-31 |
| ID27018A (id) | 2001-02-22 |
| SK16972000A3 (sk) | 2001-06-11 |
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