HUP0100647A2 - Szubsztituált 1,2,4-triazolo[3,4-a]piridazin és gyógyászati alkalmazása - Google Patents

Szubsztituált 1,2,4-triazolo[3,4-a]piridazin és gyógyászati alkalmazása

Info

Publication number
HUP0100647A2
HUP0100647A2 HU0100647A HUP0100647A HUP0100647A2 HU P0100647 A2 HUP0100647 A2 HU P0100647A2 HU 0100647 A HU0100647 A HU 0100647A HU P0100647 A HUP0100647 A HU P0100647A HU P0100647 A2 HUP0100647 A2 HU P0100647A2
Authority
HU
Hungary
Prior art keywords
triazolo
pyridazine
substituted
pharmaceutical use
methylisoxazol
Prior art date
Application number
HU0100647A
Other languages
English (en)
Inventor
William Robert Carling
Tamara Ladduwahetty
Angus Murray Macleod
Kevin John Merchant
Kevin William Moore
Francine Sternfeld
Leslie Joseph Street
Original Assignee
Merck Sharp & Dohme Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9803992.8A external-priority patent/GB9803992D0/en
Priority claimed from PCT/GB1998/001307 external-priority patent/WO1998050385A1/en
Priority claimed from GBGB9824896.6A external-priority patent/GB9824896D0/en
Application filed by Merck Sharp & Dohme Ltd. filed Critical Merck Sharp & Dohme Ltd.
Publication of HUP0100647A2 publication Critical patent/HUP0100647A2/hu
Publication of HUP0100647A3 publication Critical patent/HUP0100647A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A találmány 3-(5-metilizoxazol-3-il)-6-(1-metil-1,2,3-triazol-4-il)metiloxi-1,2,4-triazolo[3,4-a]ftalazinra, ennek felismerőképességetfokozó terápiás alkalmazására, ezt tartalmazó gyógyászatikészítményekre, és ennek előállítására szolgáló eljárásra vonatkozik. Ó
HU0100647A 1998-02-25 1999-02-17 Substituted 1,2,4-triazolo[3,4-a]pyridazine and its pharmaceutical use HUP0100647A3 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9803992.8A GB9803992D0 (en) 1998-02-25 1998-02-25 Therapeutic agents
PCT/GB1998/001307 WO1998050385A1 (en) 1997-05-08 1998-05-06 SUBSTITUTED 1,2,4-TRIAZOLO[3,4-a]PHTHALAZINE DERIVATIVES AS GABA ALPHA 5 LIGANDS
GBGB9824896.6A GB9824896D0 (en) 1998-11-12 1998-11-12 Therapeutic compound
PCT/GB1999/000485 WO1999043677A1 (en) 1998-02-25 1999-02-17 SUBSTITUTED 1,2,4-TRIAZOLO[3,4-a]PYRIDAZINE

Publications (2)

Publication Number Publication Date
HUP0100647A2 true HUP0100647A2 (hu) 2001-09-28
HUP0100647A3 HUP0100647A3 (en) 2003-03-28

Family

ID=27269184

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0100647A HUP0100647A3 (en) 1998-02-25 1999-02-17 Substituted 1,2,4-triazolo[3,4-a]pyridazine and its pharmaceutical use

Country Status (14)

Country Link
EP (1) EP1070066A1 (hu)
JP (1) JP2002504554A (hu)
CN (1) CN1291194A (hu)
AU (1) AU746719B2 (hu)
BG (1) BG104705A (hu)
CA (1) CA2317416A1 (hu)
EA (1) EA002824B1 (hu)
HR (1) HRP20000555A2 (hu)
HU (1) HUP0100647A3 (hu)
NZ (1) NZ505695A (hu)
PL (1) PL341975A1 (hu)
SK (1) SK12772000A3 (hu)
TR (1) TR200002469T2 (hu)
WO (1) WO1999043677A1 (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9821179D0 (en) * 1998-09-30 1998-11-25 Merck Sharp & Dohme Therapeutic use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI81350C (fi) * 1982-01-18 1990-10-10 Lepetit Spa Analogfoerfarande foer framstaellning av nya, farmakologiskt aktiva 6-substituerade s-triatsolo/3,4-a/ ftalazinderivat.
EP0915877A1 (en) * 1996-07-25 1999-05-19 MERCK SHARP & DOHME LTD. SUBSTITUTED TRIAZOLO PYRIDAZINE DERIVATIVES AS INVERSE AGONISTS OF THE GABA A?$g(a)5 RECEPTOR SUBTYPE
ATE221887T1 (de) * 1997-05-08 2002-08-15 Merck Sharp & Dohme Substituierte 1,2,4-triazolo(3,4,-a)phthalazin- derivate als gaba-alpha 5-liganden

Also Published As

Publication number Publication date
SK12772000A3 (sk) 2001-03-12
TR200002469T2 (tr) 2000-12-21
WO1999043677A1 (en) 1999-09-02
EP1070066A1 (en) 2001-01-24
HUP0100647A3 (en) 2003-03-28
AU746719B2 (en) 2002-05-02
HRP20000555A2 (en) 2001-08-31
EA200000878A1 (ru) 2001-02-26
BG104705A (bg) 2001-04-30
CA2317416A1 (en) 1999-09-02
NZ505695A (en) 2002-03-01
PL341975A1 (en) 2001-05-07
CN1291194A (zh) 2001-04-11
EA002824B1 (ru) 2002-10-31
AU2536899A (en) 1999-09-15
JP2002504554A (ja) 2002-02-12

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