PL341975A1 - Substituted 1,2,4-triazole[3,4-a]phtalazine - Google Patents

Substituted 1,2,4-triazole[3,4-a]phtalazine

Info

Publication number
PL341975A1
PL341975A1 PL99341975A PL34197599A PL341975A1 PL 341975 A1 PL341975 A1 PL 341975A1 PL 99341975 A PL99341975 A PL 99341975A PL 34197599 A PL34197599 A PL 34197599A PL 341975 A1 PL341975 A1 PL 341975A1
Authority
PL
Poland
Prior art keywords
phtalazine
triazole
substituted
Prior art date
Application number
PL99341975A
Inventor
William Robert Carling
Tamara Ladduwahetty
Angus Murray Macleod
Kevin John Merchant
Kevin William Moore
Francine Sternfeld
Leslie Joseph Street
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9803992.8A external-priority patent/GB9803992D0/en
Priority claimed from PCT/GB1998/001307 external-priority patent/WO1998050385A1/en
Priority claimed from GBGB9824896.6A external-priority patent/GB9824896D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of PL341975A1 publication Critical patent/PL341975A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL99341975A 1998-02-25 1999-02-17 Substituted 1,2,4-triazole[3,4-a]phtalazine PL341975A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9803992.8A GB9803992D0 (en) 1998-02-25 1998-02-25 Therapeutic agents
PCT/GB1998/001307 WO1998050385A1 (en) 1997-05-08 1998-05-06 SUBSTITUTED 1,2,4-TRIAZOLO[3,4-a]PHTHALAZINE DERIVATIVES AS GABA ALPHA 5 LIGANDS
GBGB9824896.6A GB9824896D0 (en) 1998-11-12 1998-11-12 Therapeutic compound
PCT/GB1999/000485 WO1999043677A1 (en) 1998-02-25 1999-02-17 SUBSTITUTED 1,2,4-TRIAZOLO[3,4-a]PYRIDAZINE

Publications (1)

Publication Number Publication Date
PL341975A1 true PL341975A1 (en) 2001-05-07

Family

ID=27269184

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99341975A PL341975A1 (en) 1998-02-25 1999-02-17 Substituted 1,2,4-triazole[3,4-a]phtalazine

Country Status (14)

Country Link
EP (1) EP1070066A1 (en)
JP (1) JP2002504554A (en)
CN (1) CN1291194A (en)
AU (1) AU746719B2 (en)
BG (1) BG104705A (en)
CA (1) CA2317416A1 (en)
EA (1) EA002824B1 (en)
HR (1) HRP20000555A2 (en)
HU (1) HUP0100647A3 (en)
NZ (1) NZ505695A (en)
PL (1) PL341975A1 (en)
SK (1) SK12772000A3 (en)
TR (1) TR200002469T2 (en)
WO (1) WO1999043677A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9821179D0 (en) * 1998-09-30 1998-11-25 Merck Sharp & Dohme Therapeutic use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH21834A (en) * 1982-01-18 1988-03-17 Lepetit Spa New 6-substituted-s-triazolo(3,4-a)phthalazine derivatives
US6465462B1 (en) * 1996-07-25 2002-10-15 Merck Sharp & Dohme Ltd. Substituted triazolo pyridazine derivatives as inverse agonists of the GABAAα5 receptor subtype
AU732455C (en) * 1997-05-08 2002-09-05 Merck Sharp & Dohme Limited Substituted 1,2,4-triazolo{3,4-a}phthalazine derivatives as gaba alpha 5 ligands

Also Published As

Publication number Publication date
NZ505695A (en) 2002-03-01
AU2536899A (en) 1999-09-15
TR200002469T2 (en) 2000-12-21
SK12772000A3 (en) 2001-03-12
JP2002504554A (en) 2002-02-12
EA002824B1 (en) 2002-10-31
WO1999043677A1 (en) 1999-09-02
HRP20000555A2 (en) 2001-08-31
CN1291194A (en) 2001-04-11
HUP0100647A2 (en) 2001-09-28
EA200000878A1 (en) 2001-02-26
EP1070066A1 (en) 2001-01-24
HUP0100647A3 (en) 2003-03-28
BG104705A (en) 2001-04-30
AU746719B2 (en) 2002-05-02
CA2317416A1 (en) 1999-09-02

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)