HUP0004606A2 - Kinázaktiválás-függő, ciklinfüggő kinázt aktiváló proteinkinázok és alkalmazásuk - Google Patents

Kinázaktiválás-függő, ciklinfüggő kinázt aktiváló proteinkinázok és alkalmazásuk

Info

Publication number
HUP0004606A2
HUP0004606A2 HU0004606A HUP0004606A HUP0004606A2 HU P0004606 A2 HUP0004606 A2 HU P0004606A2 HU 0004606 A HU0004606 A HU 0004606A HU P0004606 A HUP0004606 A HU P0004606A HU P0004606 A2 HUP0004606 A2 HU P0004606A2
Authority
HU
Hungary
Prior art keywords
protein kinases
kinase activating
cyclin protein
protein kinase
dependent cyclin
Prior art date
Application number
HU0004606A
Other languages
English (en)
Inventor
Gérard Faye
Carl Mann
Jean-Yves Thuret
Jean Gabriel Valay
Original Assignee
Centre National De La Recherche Scientifique
Commissariat A L`Energie Atomique
Institut Curie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National De La Recherche Scientifique, Commissariat A L`Energie Atomique, Institut Curie filed Critical Centre National De La Recherche Scientifique
Publication of HUP0004606A2 publication Critical patent/HUP0004606A2/hu
Publication of HUP0004606A3 publication Critical patent/HUP0004606A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgya CIV1 családba tartozó proteinkináz, amely - nem tartalmaz GxGx(Y/F)GxV motívumot, és - aktivitása nem ciklinfüggő CAK-aktivitás. A találmány szerintiproteinkináz különbözik a Saccharomyces cerevisiae<> CAK-tól, azScCIV1-től. A találmány szerinti proteinkinázok inhibitoraifungicidekként alkalmazhatók. Ó
HU0004606A 1997-08-12 1998-08-11 Kinase activating dependent cyclin protein kinases, and their uses HUP0004606A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9710287A FR2767334B1 (fr) 1997-08-12 1997-08-12 Kinase activatrice des proteine-kinases cycline dependantes, et ses utilisations
PCT/FR1998/001788 WO1999007836A1 (fr) 1997-08-12 1998-08-11 Kinase activatrice des proteine-kinases cycline dependantes, et ses utilisations

Publications (2)

Publication Number Publication Date
HUP0004606A2 true HUP0004606A2 (hu) 2001-04-28
HUP0004606A3 HUP0004606A3 (en) 2005-11-28

Family

ID=9510243

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004606A HUP0004606A3 (en) 1997-08-12 1998-08-11 Kinase activating dependent cyclin protein kinases, and their uses

Country Status (24)

Country Link
US (1) US6413754B1 (hu)
EP (1) EP1003844B1 (hu)
JP (1) JP2001512677A (hu)
KR (1) KR20010022505A (hu)
CN (1) CN1149281C (hu)
AP (1) AP1089A (hu)
AT (1) ATE318302T1 (hu)
AU (1) AU751829B2 (hu)
BR (1) BR9811169A (hu)
CA (1) CA2300439A1 (hu)
CZ (1) CZ291968B6 (hu)
DE (1) DE69833556D1 (hu)
EA (1) EA004710B1 (hu)
FR (1) FR2767334B1 (hu)
HU (1) HUP0004606A3 (hu)
IL (1) IL134344A0 (hu)
NO (1) NO20000687D0 (hu)
NZ (1) NZ502720A (hu)
PL (1) PL338684A1 (hu)
SK (1) SK1922000A3 (hu)
TR (1) TR200000337T2 (hu)
WO (1) WO1999007836A1 (hu)
YU (1) YU7500A (hu)
ZA (1) ZA987206B (hu)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030104362A1 (en) * 1995-06-05 2003-06-05 Guillaume Cottarel Cell-cycle regulatory proteins from human pathogens, and uses related thereto
FR2818642B1 (fr) * 2000-12-26 2005-07-15 Hoechst Marion Roussel Inc Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilistion
KR100677396B1 (ko) * 2004-11-20 2007-02-02 엘지전자 주식회사 음성인식장치의 음성구간 검출방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733920A (en) * 1995-10-31 1998-03-31 Mitotix, Inc. Inhibitors of cyclin dependent kinases

Also Published As

Publication number Publication date
EA200000213A1 (ru) 2000-08-28
WO1999007836A1 (fr) 1999-02-18
PL338684A1 (en) 2000-11-20
ATE318302T1 (de) 2006-03-15
HUP0004606A3 (en) 2005-11-28
CZ2000491A3 (cs) 2000-07-12
NO20000687L (no) 2000-02-11
BR9811169A (pt) 2000-07-25
ZA987206B (en) 1999-02-12
CA2300439A1 (fr) 1999-02-18
JP2001512677A (ja) 2001-08-28
IL134344A0 (en) 2001-04-30
FR2767334B1 (fr) 1999-10-22
CN1266456A (zh) 2000-09-13
EP1003844A1 (fr) 2000-05-31
EP1003844B1 (fr) 2006-02-22
SK1922000A3 (en) 2000-11-07
AP2000001768A0 (en) 2000-03-31
AU751829B2 (en) 2002-08-29
FR2767334A1 (fr) 1999-02-19
DE69833556D1 (de) 2006-04-27
NO20000687D0 (no) 2000-02-11
KR20010022505A (ko) 2001-03-15
CZ291968B6 (cs) 2003-06-18
EA004710B1 (ru) 2004-06-24
US6413754B1 (en) 2002-07-02
NZ502720A (en) 2001-01-26
AU9075098A (en) 1999-03-01
AP1089A (en) 2002-08-01
YU7500A (sh) 2003-07-07
TR200000337T2 (tr) 2000-09-21
CN1149281C (zh) 2004-05-12

Similar Documents

Publication Publication Date Title
ATE306487T1 (de) Purinhemmer von cyclinabhängiger kinase 2 und ikb-alpha
WO1999006540A3 (en) Inhibitors of cell-cycle progression and uses related thereto
WO2004026229A3 (en) Pyrazolo[1,5-a]pyrimidines compounds as cyclin dependent kinase inhibitors
NO20022864L (no) Aminotiazol inhibitorer av syklin uavhengig kinase
WO1995033819A3 (en) Cdk4 (cyclin dependent kinase 4) binding proteins
DE60039616D1 (de) INHIBITOREN DER c-JUN N-TERMINALEN KINASE (JNK) UND ANDERE PROTEIN-KINASEN
MXPA04003668A (es) Inhibidores de fosfodiesteresa de tipo 4 y usos de los mismos.
MY141978A (en) Pyrazolopyrimidines as cyclin dependent kinase inhibitors
BRPI0314001B8 (pt) pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas
YU49315B (sh) Inhibitor protein kinaze c, njegove farmaceutske formulacije i postupak za dobijanje
MY149044A (en) Pyrazolopyrimidines - derivatives as cyclin dependent kinase inhibitors
PL309358A1 (en) Substituted aminopyrazoles exhibiting antagonistic activity in respect to crf
PT888353E (pt) Novas n-7-heterociclil-pirrolo¬2,3-d|pirimidinas e sua aplicacao
EA200201096A1 (ru) СОЕДИНЕНИЯ ПИРРОЛО[2,3-d]ПИРИМИДИНА В КАЧЕСТВЕ ИММУНОДЕПРЕССАНТОВ
HUP0104483A2 (hu) Fungicid hatóanyagkombinációk és alkalmazásuk
WO2001049688A8 (en) Purine derivatives, process for their preparation and use thereof
BR0107403A (pt) Compostos de n-(5,7-dimetóxi[1,2,4] triazolo[1,5-alfa]pirimidin-2-il)arilsulfonamida e o uso dos mesmos como herbicidas
DE69905712T2 (de) Verwendung von indigoähnlichen bisindolen zur herstellung eines arzneimittels zur hemmung cyclin abhängiger kinasen
CO4290432A1 (es) Nuevos derivados de pirazinacarboxamida, su preparacion y su utilizacion en medicamentos.
ATE250602T1 (de) Pyrimido(6,1-a)isochinolinonderivate
ATE309223T1 (de) Cyclin-abhängige kinase inhibitoren
HUP0301032A3 (en) N-[5-[[[5-alkyl-2-oxazolyl]methyl]thio]-2-thiazolyl]-carboxamide inhibitors of cyclin dependent kinases, their use and pharmaceutical compositions containing them
TR199802649A2 (xx) Sikline ba�l� kinazlar�n inhibit�rleri i�in ba�lama e�leri.
HUP0004606A2 (hu) Kinázaktiválás-függő, ciklinfüggő kinázt aktiváló proteinkinázok és alkalmazásuk
WO1996002240A3 (en) Use of inhibitors of human s-cd23

Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished