HUP0001866A2 - L-Karnitin és alkanoil-L-karnitin-származékok 2-amino-etánszulfonsavval alkotott sói és ezeket tartalmazó gyógyszerkészítmények - Google Patents

L-Karnitin és alkanoil-L-karnitin-származékok 2-amino-etánszulfonsavval alkotott sói és ezeket tartalmazó gyógyszerkészítmények

Info

Publication number
HUP0001866A2
HUP0001866A2 HU0001866A HUP0001866A HUP0001866A2 HU P0001866 A2 HUP0001866 A2 HU P0001866A2 HU 0001866 A HU0001866 A HU 0001866A HU P0001866 A HUP0001866 A HU P0001866A HU P0001866 A2 HUP0001866 A2 HU P0001866A2
Authority
HU
Hungary
Prior art keywords
carnitine
salts
alkanoyl
aminoethanesulfonic acid
pharmaceutical compositions
Prior art date
Application number
HU0001866A
Other languages
English (en)
Inventor
Nazareno Scafetta
Maria Ornella Tinti
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of HUP0001866A2 publication Critical patent/HUP0001866A2/hu
Publication of HUP0001866A3 publication Critical patent/HUP0001866A3/hu
Publication of HU226109B1 publication Critical patent/HU226109B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/175—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Cardiology (AREA)
  • Food Science & Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Nutrition Science (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)

Abstract

A találmány az (I) általános képletű, 2-amino-etánszulfonsavvalalkotott L-karnitin- vagy alkanoil-L-karnitin-sókra - ahol a képletbenR jelentése hidrogénatom vagy 2-5 szénatomot tartalmazó, egyenes vagyelágazó láncú alkanoilcsoport - vonatkozik. A találmány továbbá olyankészítményekre vonatkozik, amelyek hatóanyagként az említett sókvalamelyikét, továbbá egy vagy több, a gyógyszergyártásban szokásosanhasznált hordozó- és/vagy egyéb segédanyagot és hatóanyagottartalmaznak. A találmány szerinti készítmények felhasználhatók humáncélokra az étrend kiegészítőjeként, illetve állatgyógyászati célokratakarmánykiegészítőként. Ó
HU0001866A 1997-04-01 1998-03-19 Salts of l-carnitine and alkanoyl-l-carnitine derivatives with 2-aminoethanesulfonic acid and pharmaceutical compositions containing them HU226109B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97RM000184A IT1291126B1 (it) 1997-04-01 1997-04-01 Composizioni solide atte alla somministrazione orale comprendenti sali non igroscopici della l-carnitina e delle alcanoil l-carnitine
PCT/IT1998/000060 WO1998043945A1 (en) 1997-04-01 1998-03-19 Solid compositions suitable for oral administration comprising non hygroscopic salts of l-carnitine and alkanoyl-l-carnitine with 2-aminoethanesulfonic acid

Publications (3)

Publication Number Publication Date
HUP0001866A2 true HUP0001866A2 (hu) 2000-11-28
HUP0001866A3 HUP0001866A3 (en) 2002-09-30
HU226109B1 HU226109B1 (en) 2008-04-28

Family

ID=11404924

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0001866A HU226109B1 (en) 1997-04-01 1998-03-19 Salts of l-carnitine and alkanoyl-l-carnitine derivatives with 2-aminoethanesulfonic acid and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US6124360A (hu)
EP (1) EP0971880B1 (hu)
JP (1) JP4047935B2 (hu)
KR (1) KR100562055B1 (hu)
CN (1) CN1187318C (hu)
AT (1) ATE210111T1 (hu)
AU (1) AU733272B2 (hu)
BR (1) BR9808461A (hu)
CA (1) CA2285380C (hu)
CZ (1) CZ296465B6 (hu)
DE (1) DE69802789T2 (hu)
DK (1) DK0971880T3 (hu)
ES (1) ES2167878T3 (hu)
HK (1) HK1025560A1 (hu)
HU (1) HU226109B1 (hu)
IL (2) IL131956A0 (hu)
IT (1) IT1291126B1 (hu)
NZ (1) NZ500537A (hu)
PL (1) PL189488B1 (hu)
PT (1) PT971880E (hu)
SI (1) SI0971880T1 (hu)
SK (1) SK283392B6 (hu)
WO (1) WO1998043945A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090849A (en) * 1999-03-23 2000-07-18 The Board Of Regents For Oklahoma State University Carnitine supplemented diet to prevent sudden death syndrome in breeder type poultry
IT1305308B1 (it) * 1999-03-26 2001-05-04 Biosint S P A Granulato ad alto contenuto di l-carnitina o alcanoil-l-carnitina,particolarmente adatto alla produzione di compresse per compressione
IT1317924B1 (it) 2000-10-31 2003-07-15 Sigma Tau Ind Farmaceuti Composizioni solide atte alla somministrazione orale comprendenti salinon igroscopici della l-carnitina e delle alcanoil l-carnitine con
DE20321010U1 (de) * 2003-03-28 2005-12-29 Schymura, Martin Fruchtgummizusammensetzung
CN104276986B (zh) * 2013-07-12 2016-07-06 辽宁科硕营养科技有限公司 左旋肉碱牛磺酸盐的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1153640A (en) * 1967-04-10 1969-05-29 Soc D Etudes Prod Chimique A Carnitin Salt
FR2529545B1 (fr) * 1982-07-02 1985-05-31 Sanofi Sa Nouveaux sels de carnitine ainsi que leur procede de preparation
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
IT1188176B (it) * 1985-07-05 1988-01-07 Bicresearch Spa Sali della carnitina particolarmente idonei per uso orale
SE8701662L (sv) * 1987-04-22 1988-10-23 Gelder Nico M Van Saett och medel foer att behandla neurologiska sjukdomar, exempelvis migraen genom paaverkan av nervcellerna
CA2018137C (en) * 1989-06-14 2000-01-11 Thomas Scholl L-carnitine magnesium citrate
US5073376A (en) * 1989-12-22 1991-12-17 Lonza Ltd. Preparations containing l-carnitine
US5571783A (en) * 1993-03-09 1996-11-05 Clintec Nutrition Company Composition and method for treating patients with hepatic disease
IT1261688B (it) * 1993-05-28 1996-05-29 Avantgarde Spa Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.
US5589468A (en) * 1995-01-13 1996-12-31 Clintec Nutrition Co. Method for providing nutrition to elderly patients

Also Published As

Publication number Publication date
CZ296465B6 (cs) 2006-03-15
US6124360A (en) 2000-09-26
SI0971880T1 (en) 2002-06-30
NZ500537A (en) 2001-03-30
DK0971880T3 (da) 2002-03-04
EP0971880A1 (en) 2000-01-19
BR9808461A (pt) 2000-05-23
EP0971880B1 (en) 2001-12-05
ES2167878T3 (es) 2002-05-16
HU226109B1 (en) 2008-04-28
ITRM970184A1 (it) 1998-10-01
IT1291126B1 (it) 1998-12-29
JP2001517227A (ja) 2001-10-02
CN1187318C (zh) 2005-02-02
PL189488B1 (pl) 2005-08-31
CA2285380A1 (en) 1998-10-08
SK135099A3 (en) 2000-05-16
SK283392B6 (sk) 2003-07-01
HK1025560A1 (en) 2000-11-17
PL335937A1 (en) 2000-05-22
WO1998043945A1 (en) 1998-10-08
DE69802789D1 (de) 2002-01-17
CN1251573A (zh) 2000-04-26
PT971880E (pt) 2002-05-31
AU6745598A (en) 1998-10-22
CA2285380C (en) 2008-07-08
HUP0001866A3 (en) 2002-09-30
AU733272B2 (en) 2001-05-10
CZ347899A3 (cs) 2000-04-12
KR100562055B1 (ko) 2006-03-17
IL131956A0 (en) 2001-03-19
ATE210111T1 (de) 2001-12-15
DE69802789T2 (de) 2002-07-18
KR20010005867A (ko) 2001-01-15
IL131956A (en) 2007-09-20
JP4047935B2 (ja) 2008-02-13

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